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Assessment of intracellular pH and fermentation profile in xylose-fermenting Saccharomyces cerevisiae strains using ratiometric sensors

The production of ethanol from second-generation feedstock like lignocellulose is limited by efficient growth of Saccharomyces cerevisiae on xylose. One of the reasons for that might be a lower ATP formation vs. proton formation flux in cells using the xylose reductase (XR)/xylose dehydrogenase (XDH) pathway compared to glucose as ideal substrate. The therefore reduced availability of ATP, as ATP

The Controversial Interface between Competition and Data Protection Law - An Analysis of Privacy Concerns in the context of Merger Control

In the digital market, data has become an invaluable asset that businesses strive to achieve. Since most of the data acquired is personal data, current legal and academic debates have begun to investigate whether and how privacy is addressed within the context of merger control. The purpose of this thesis is to shed light on the role of competition law in safeguarding consumers from potential priv

A Transformation in Education? A comparative analysis of SDG4 implementation in domestic contexts.

Progress on Sustainable Development Goal 4: Quality Education (SDG4) has been insufficient and knowledge of how it is implemented into domestic contexts remains limited. Using norm diffusion theory as a framework, this thesis is a comparative study of SDG4 implementation in five countries around the world. By analysing both the discursive and practical impact of SDG4, this thesis has studied if an

Molecular and cellular mechanisms of chemoresistance in pancreatic cancer

Pancreatic Ductal Adenocarcinoma (PDAC) is one of the most chemoresistant cancers, and current therapies targeting cancer-associated molecular pathways have not given satisfactory results, owing in part to rapid upregulation of alternative compensatory pathways. Most of the available treatments are palliative, focussing on improving the quality of life. At present, available options are surgery, e

Anti-phosphatidylserine antibody levels are low in multigravid pregnant women in a malaria-endemic area in Nigeria, and do not correlate with anti-VAR2CSA antibodies

Anemia is a common malaria-associated complication in pregnant women in endemic regions. Phosphatidylserine (PS) is exposed to the immune system during the massive destruction of red blood cells (RBCs) that accompany malaria, and antibodies against PS have been linked to anemia through destruction of uninfected RBCs. We determined levels of anti-PS IgG antibodies in pregnant women in Ibadan, Niger

Investigating the Feasibility of using Scandinavian Agricultural Side Streams for the Development of Novel High-Moisture Meat Analogues

Meat analogues are products that are supposed to resemble meat in terms of texture, flavour, and also sensory characteristics. They have recently become increasingly popular due to numerous issues related to health, religion, environmental impact and the growing number of vegetarians and vegans. Due to this reason, many plant-based protein materials, including grains, legumes, microalgae, and mush

Using an ionomer as a size regulator in γ-radiation induced synthesis of Ag nanocatalysts for oxygen reduction reaction in alkaline solution

Ag nanoparticles (Ag NPs) are among the most promising candidates to replace Pt as the catalyst for the oxygen reduction reaction (ORR) in anion exchange membrane fuel cells (AEMFCs). However, synthesizing size-controlled Ag NPs with efficient catalytic performance is still challenging. Herein, uniform Ag NPs are produced through a γ-radiation induced synthesis route in aqueous solutions, using th

Handbook of Nuclear Medicine and Molecular Imaging for Physicists : Instrumentation and Imaging Procedures, Volume I

This state-of-the-art handbook, the first in a series that provides medical physicists with a comprehensive overview into the field of nuclear medicine, is dedicated to instrumentation and imaging procedures in nuclear medicine. It provides a thorough treatment on the cutting-edge technologies being used within the field, in addition to touching upon the history of their use, their development, an

Covalent Adaptable Polymethacrylate Networks by Hydrazide Crosslinking Via Isosorbide Levulinate Side Groups

Reversible crosslinking offers an attractive strategy to modify and improve the properties of polymer materials while concurrently enabling a pathway for chemical recycling. This can, for example, be achieved by incorporating a ketone functionality into the polymer structure to enable post-polymerization crosslinking with dihydrazides. The resulting covalent adaptable network contains acylhydrazon

Insights in α-Al2O3 degradation in multilayer CVD coated carbide tools when turning IN718

The degradation behaviour of textured CVD α-alumina has received significant attention within academic literature with regard to steel turning. In contrast, the research performed on Ni-based superalloys is yet to be brought up to the same level of understanding. Hence, the objective of this report will be to offer insights with regard to the degradation mechanisms of the textured alumina layer of

Succession of bacterial biofilm communities following removal of chloramine from a full-scale drinking water distribution system

Monochloramine is used to regulate microbial regrowth in drinking water distribution systems (DWDS) but produces carcinogenic disinfection byproducts and constitutes a source of energy for nitrifying bacteria. This study followed biofilm-dispersed microbial communities of a full-scale DWDS distributing ultrafiltered water over three years, before and after removal of monochloramine. Communities we

Actively controlled cardiac afterload

Ex vivo (outside of the body) working heart models enable the evaluation of isolated hearts. They are envisioned to play an important role in increasing the currently low utilization rate of donor hearts for transplantation. For the heart to work in isolation, an afterload (flow impedance) is needed. To date, afterload devices have been constructed by combining multiple constituent elements such a

Towards a Deflationary Truthmakers Account of Social Groups

I outline a deflationary truthmakers account of social groups. Potentially, the approach allows us to say, with traditional ontological individualists, that there are only pluralities of individuals out there, ontologically speaking, but that there are nevertheless colloquial and social-scientific truths about social groups. If tenable, this kind of theory has the virtue of being both ontologicall