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The lack of any effective therapy along with the aging world population anticipates a growth of the worldwide incidence of Alzheimer's disease (AD) to more than 100 million cases by 2050. Accumulation of extracellular amyloid-β (Aβ) plaques, intracellular tangles in the brain, and formation of reactive oxygen species (ROS) are the major hallmarks of the disease. In the amyloidogenic process, a β-s

This article provides an overview on established membrane applications in the food industry and focuses on applications of membrane processes in the production of beer, wine, fruit juice, food additives, and dairy products such as milk, whey, and cheese. Furthermore, as the food industry is a highly water consuming industry one section of this article is dedicated to water preparation and wastewat

Pressure-solution creep is one of the most common crustal deformation mechanisms, inducing changes in the porosity and permeability of rocks. For a variety of rock types undergoing pressure solution, it has been shown that the presence of phyllosilicates may significantly enhance the rate of the pressure-solution process. In this experimental investigation, we present 4-dimensional (three dimensio

Exposure to UV light triggers the rapid generation and accumulation of reactive oxygen species (ROS) in skin cells, with consequent increase in oxidative stress and thus in photoaging. Exogenous supplementation with dietary antioxidants and/or skin pretreatment with antioxidant-based lotions before sun exposure might be a winning strategy against age-related skin pathologies. In this context, plan

Membrane fouling and its control is one of the most critical parameters in the application of membrane processes. The degree of fouling depends on the application and on industrial scale, fouling is often observed as reduction in plant capacity over time. One approach to reduce fouling for the pressure driven processes microfiltration and ultrafiltration is to use hydrophilic membranes. This paper

The recent developments in the field of biorefineries open new opportunities for the pulp and paper industry to diverse from classical carton and paper production to bio-based chemicals. The trend is thus to use the three key wood components hemicelluloses, lignin and cellulose as raw materials for production of a wide range of biochemicals. A key success factor is the integration of energy-effici

Despite strong scientific evidence supporting the benefits of regular exercise for the prevention and management of cardiovascular disease (CVD), physical inactivity is highly prevalent worldwide. In addition to merely changing well-known risk factors for systemic CVD, regular exercise can also improve cardiovascular health through non-traditional mechanisms. Understanding the pathways through whi

In recent years biorefineries using lignocellulosic biomass such as wood and agricultural residuals as raw material have gained significant interest since they avoid competition with food production. One of the key development areas of these lignocellulosic based biorefinery concepts is the integration low energy and high selective separation processes. Thus, membrane processes either as stand-alo

1. IntroductionThe third wave of biotechnology – white biotechnology – started with the end of the 20th century with the goal to replace conventional chemical processes based on C2/C3 chemistry by biotechnological processes. In biotechnology fermentation is used as standard conversion process for the production of bulk fermentation products such as antibiotics, enzymes, bioethanol and organic acid

Background: Improvement in the surgical system requires intersectoral coordination. To achieve this, the development of National Surgical, Obstetric, and Anaesthesia Plans (NSOAPS) has been recommended. One of the first steps of NSOAP development is situational analysis. On the ground situational analyses can be resource intensive and often duplicative. In 2016, the Ministry of Health of Tanzania

Observational learning is a successful method for improving writing skills in various genres. We explore effects of a five lesson intervention series based on peer observation. Fifty-five Swedish 5th-grade students aged 10-12 years followed this intervention program. The language and reading comprehension and working memory capacity were tested. The students watched short film-clips with peers wor

Mutations in NPM1 can be used for minimal residual disease (MRD) analysis in acute myeloid leukemia (AML). We here applied a newly introduced method, deep sequencing, allowing for simultaneous analysis of all recurrent NPM1 insertions and thus constituting an attractive alternative to multiple PCRs for the clinical laboratory. We retrospectively used deep sequencing for measurement of MRD pre- and