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A Comparison of 111In-J591 SPECT with 89Zr-J591 PET Imaging for Prostate Cancer Patients

Introduction and Objectives: To compare pilot cohorts of men scheduled for radical prostatectomy imaged with novel antibody conjugates: Cohort 1 (111In-J591) single photon emission tomography (SPECT) or Cohort 2 (89Zr-J591) positron emission tomorgraphy (PET).Methods: 1) Cohort 1: Eight patients with abnormal digital rectal exam and biopsy proven prostate cancer were injected intravenously with tw

Effects of Word Definitions on Meaning Recall : A Multisite Intervention in Language-Diverse Second Language English Classrooms

Vocabulary experts recommend first language (L1) translation equivalents for establishing form–meaning mappings for new second language (L2) words, especially for lower proficiency learners. Empirical evidence to date speaks in favor of L1 translation equivalents over L2 meaning definitions, but most studies have investigated bi- rather than multilingual learners. In our study, we investigated ins

Early Versus Delayed Non-Vitamin K Antagonist Oral Anticoagulant Therapy after Acute Ischemic Stroke in Atrial Fibrillation (TIMING) : A Registry-Based Randomized Controlled Noninferiority Study

Background: There are no evidence-based recommendations on the optimal time point to initiate non-vitamin K antagonist oral anticoagulants (NOACs) after acute ischemic stroke in patients with atrial fibrillation. We aimed to investigate the efficacy and safety of early versus delayed initiation of NOAC in these patients. Methods: TIMING (Timing of Oral Anticoagulant Therapy in Acute Ischemic Strok

Immortal Beloved : Virtue, Death, and the Making of the Swedish Nineteenth-Century Pedagogical Scholar

This article analyses the creation of a new template for pedagogical scholars during the early decades of the nineteenth century in Sweden, encased in the tragic persona of Carl Ulric Broocman. Broocman, one of the most influential pedagogical scholars of his time, died at the peak of his career and was posthumously cast as a perfect teacher and scholar in his obituary. On closer inspection, the o

Unified Theory of Characteristic Modes : Part II - Tracking, Losses, and FEM Evaluation

This is the second component of a two-part paper dealing with a unification of characteristic mode decomposition. This second part addresses modal tracking, interpolation, the role of ohmic losses, and presents several numerical examples for surface-based method-of-moment formulations. A new tracking algorithm based on algebraic properties of the transition matrix is developed, achieving excellent

‘Making room for student autonomy’ – an ethnographic study of student participation in clinical work

Participation in clinical work is important for medical students’ professional development. However, students often report that they experience a passive observer role, and further research on contextual factors that influence student participation is needed. The theory of practice architectures contributes a new perspective to this challenge by elucidating how cultural-discursive, material-econom

An Interdisciplinary Perspective on Evaluation and Experimental Design for Visual Text Analytics : Position Paper

Appropriate evaluation and experimental design are fundamental for empirical sciences, particularly in data-driven fields. Due to the successes in computational modeling of languages, for instance, research outcomes are having an increasingly immediate impact on end users. As the gap in adoption by end users decreases, the need increases to ensure that tools and models developed by the research co

Molecular and Morphological Characteristics of the De-Obstructed Rat Urinary Bladder—An Update

Many patients with outlet obstruction secondary to prostatic enlargement have lower urinary tract symptoms (LUTSs) and an increased frequency of micturition. The standard treatment is transurethral resection of the prostate (TURP), which alleviates obstruction and symptoms. However, after TURP, 20–40 percent of patients continue to experience LUTSs. The aim of the present study in rats was to iden

Paving the Road to Flex and Biomass : The Land Surface Carbon Constellation Study

Remote sensing observations of variables related to vegetation at microwave and optical/infrared wavelengths are presented over three regions in Europe in the Iberian peninsula, northern Finland and central Europe. They include the instrumented sites of Las Majadas, Sodankyla and Reusel. The final goal is to better constrain land carbon cycle models using the complementarities of vegetation optica

Långt kvar till cirkulär framtid

Ungefär hälften av ­människans klimatavtryck kan kopplas till vårt slit-och-släng-samhälle. En åberopad lösning är en övergång till cirkulär ekonomi – men dit är det långt kvar. Under tiden växer avfallsmängderna, inte minst från elektronikhandeln, som pekas ut som ett särskilt bekymmer.

General time-dependent configuration-interaction singles. II. Atomic case

We present a specialization of the grid-based implementation of the time-dependent configuration-interaction singles described in the preceding paper [S. Carlström et al., preceding paper, Phys. Rev. A 106, 043104 (2022)]10.1103/PhysRevA.106.043104. to the case of spherical symmetry. We describe the intricate time propagator in detail and conclude with a few example calculations. Among these, of n

Joint Handwritten Text Recognition and Word Classification for Tabular Information Extraction

In this paper, we present a system for extracting tabular information from loosely structured handwritten documents. The system consists of three parts, (i) a u-net like CNN-based method for text detection and segmentation, (ii) a new attention-based method for simultaneous text recognition and classification of word-parts, and (iii) a method for matching the word parts into a tabular structure fo

Water use efficiency control for a maize field under mulched drip irrigation

Agricultural ecosystem water use efficiency (WUE) is an important indicator reflecting carbon-water coupling, but its control mechanisms in managed fields remain unclear. In order to reveal the influencing factors of WUE in the agricultural field under mulched drip irrigation (DM), we carried out the 8-year continuous observations in a maize field from Northwestern China. The structural equation m

Local municipalities and the influence of national networks on city climate governance : Small places with big possibilities

Reaching the 1.5°C target of the Paris Agreement not only requires ambitious goals from national governments, but also the active participation of local municipalities. It is in cities where climate actions need to be implemented to reduce greenhouse gas emissions and reach international and national climate goals. While the importance of cities and their participation in networks has been well-re

Indirect effect of alpha-1-antitrypsin on endotoxin-induced IL-1β secretion from human PBMCs

Human alpha-1-antitrypsin (AAT) encoded by the SERPINA1 gene, is an acute phase glycoprotein that regulates inflammatory responses via both protease inhibitory and non-inhibitory activities. We previously reported that AAT controls ATP-induced IL-1β release from human mononuclear cells by stimulating the release of small bioactive molecules. In the current study, we aimed to elucidate the identity

Atmospherically Relevant Chemistry and Aerosol box model - ARCA box (version 1.2)

We introduce the Atmospherically Relevant Chemistry and Aerosol box model ARCA box (v.1.2.2). It is a zero-dimensional process model with a focus on atmospheric chemistry and submicron aerosol processes, including cluster formation. A novel feature in the model is its comprehensive graphical user interface, allowing for detailed configuration and documentation of the simulation settings, flexible