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Histopathological dimensions differ between aganglionic and ganglionic bowel wall in children with Hirschsprung’s disease

Background: In the validation of new imaging technology for children with Hirschsprung’s disease (HSCR), basic anatomical parameters of the bowel wall must be established specifically for this patient group. Aim: To explore differences in histoanatomical layers of bowel wall, comparing ganglionic and aganglionic bowel walls, and to examine if the bowel wall thickness is linked to patient weight. M

Revised function analysis of sustainability : understanding the complexity of sustainability.

This article presents and discusses the case study “Scraping the surface,” aworkshop about sustainable design held for master’s students of different design majors at the FHNW Academy of Art and Design. Through marketing we, as consumers, are bombarded with products claiming to be sustainable. As a result, sustainability has become a buzz word. “Scraping the surface” highlighted the complex factor

The relevance of rich club regions for functional outcome post-stroke is enhanced in women

This study aimed to investigate the influence of stroke lesions in predefined highly interconnected (rich-club) brain regions on functional outcome post-stroke, determine their spatial specificity and explore the effects of biological sex on their relevance. We analyzed MRI data recorded at index stroke and ~3-months modified Rankin Scale (mRS) data from patients with acute ischemic stroke enrolle

Steel Beyond Coal : Socio-Technical Change and the Emergent Politics of Steel Decarbonisation

The steel industry is responsible for 8% of all anthropogenic greenhouse gas emissions and is the second largest user of coal after the power sector. The main emission source in steel production is the blast furnace, which converts iron ore and metallurgical coal into pig iron that is then further refined into steel. Past efforts to reduce emissions from steel have focussed on increasing energy ef

Craft brewery leaders for transformation towards sustainability? A case study of transformative qualities, and hindering or enabling factors for action in craft brewery leaders in Sweden and Germany.

The internal dimension of an individual is a potential deep leverage point for a collective change toward sustainability that is currently overlooked. Especially in their professional context, certain individuals can create change beyond themselves and the enterprise subjected to them. The environment of individuals, however, influences the activated potential of individuals for contributing to th

Sentiment analysis, topic modelling and social network analysis : COVID-19, protest movements and the Polish Tweetosphere

Extensive anti-government protests were held in Poland in October 2020 related to accumulated social tensions due to COVID-19 pandemic among others. We attempt a question of how understanding communication patterns among protesters could possibly support epidemiological harm reduction campaigns. To do so, we analysed tweets in Polish language with hashtags: #Strajkkobiet representing pro-choice mo

Yangon Stories

Since the colonial period spatial violence has been a regular occurrence for people throughout Yangon (Rangoon). These acts, led by successive state powers have only increased. Since 2021, the scale of these violences are unprecedented and country wide displaying raw brutality exerted by the junta.Yangon Stories is a collaborative research project aimed at documenting and bearing witness to the sp

Copy number signatures for early diagnosis of high-grade serous ovarian carcinoma

BackgroundThe detection of ovarian carcinoma-derived somatic mutations in cervical samples and uterine lavages in several studies since 2013, has brought hope for the development of new biomarkers for early detection. High-grade serous ovarian carcinoma (HGSC) is strongly dominated by copy number alterations (CNAs). These CNAs are the consequence of underlying mutational processes in HGSC. We inte

Quadrotor Control on SU(2)× R3with SLAM Integration

We present a trajectory tracking controller for a quadrotor unmanned aerial vehicle (UAV) configured on SU(2) × R3, and relate this result to a family of geometric tracking controllers on SO(3) × R3. The theoretical results are verified in several simulation examples, and the controller is subsequently implemented in practice and integrated with a simultaneous localization and mapping (SLAM) syste

Revisiting Proportionality in International and European Law : Interests and Interest- Holders

This book casts new light on the application of the principle of proportionality in international law. Proportionality is claimed to play a central role in governing the exercise of public power in international law and has been presented as the ‘ultimate rule of law’. It has also been the subject of fierce criticism: it is argued that it leads to unreflexive and arbitrary application of the law a

Clinical, demographic and theory-derived maintaining factors as moderators of treatment outcome in internet-delivered cognitive behavioural therapy for children and adolescents with social anxiety disorder

Internet-delivered cognitive behavioural therapy (ICBT) is an efficacious treatment for social anxiety disorder (SAD) in youth. However, we have limited knowledge about patient characteristics that may be associated with better (or worse) treatment outcome. Particularly concerning factors suggested to be involved in the maintenance of SAD (e.g., anticipatory anxiety and post-event processing). The

Perceived Consequences of Post-COVID-19 and Factors Associated with Low Life Satisfaction

A significant number of individuals experience post-COVID-19 symptoms, but knowledge of perceived consequences and life satisfaction is lacking. Here, we investigate perceived consequences regarding everyday life, health, physical activity and work post-COVID-19 and factors associated with low life satisfaction. A total of 766 people (mean age 48; 672 women) experiencing post-COVID-19 symptoms at

Simulating Vapor-Liquid-Solid Growth of Au-Seeded InGaAs Nanowires

Ternary III-V nanowires are commonly grown using the Au-seeded vapor-liquid-solid method, wherein the solid nanowires are grown from nanoscale liquid seed particles, which are supplied with growth species from the surrounding vapor phase. A result of the small size of these seed particles is that their composition can vary significantly during the cyclical layer-by-layer growth, despite experienci

Histology-based blood leukocyte profiling reveals parallel Th2 and Th17 signatures in seasonal allergic rhinitis

BACKGROUND: Allergic rhinitis (AR), a common condition in the westernized world, is suggested to be more immunologically complex than the archetypical 'Th2' inflammation. New approaches are needed to decode this complexity.AIMS/OBJECTIVES: In this study, we explored a novel histology-based analysis for circulating blood leukocyte profiling in 16 patients with seasonal AR outside and during the pol

Level of sedation in critically ill adult patients : a protocol for a systematic review with meta-analysis and trial sequential analysis

Introduction It is standard of care to provide sedation to critically ill patients to reduce anxiety, discomfort and promote tolerance of mechanical ventilation. Given that sedatives can have differing effects based on a variety of patient and pharmacological characteristics, treatment approaches are largely based on targeting the level of sedation. The benefits of differing levels of sedation mus

Multi-camera platform calibration using multi-linear constraints

We present a novel calibration method for multi-camera platforms, based on multi-linear constraints. The calibration method can recover the relative orientation between the different cameras on the platform, even when there are no corresponding feature points between the cameras, i.e. there are no overlaps between the cameras. It is shown that two translational motions in different directions are