In this study, an algae biomass gasification process using a dual fluidized bed with combined power and methanol cogeneration was developed. The gasification process was modeled using Aspen Plus and validated using experimental data of two microalgae species (Nannochloropsis oculata and Dunaliella salina) commonly found on the western coast of Saudi Arabia. The impacts of different operating condi

Treatment of melanoma with a BRAF inhibitor (BRAFi) frequently initiates development of BRAFi resistance, leading to increased tumor progression and metastasis. Previously, we showed that combined inhibition of elevated WNT5A and IL-6 signaling reduced the invasion and migration of BRAFi-resistant (BRAFi-R) melanoma cells. However, the use of a combined approach per se and the need for high inhibi

In this study, a numerical model is developed to investigate the active-pressurization performance in a liquid oxygen tank. The VOF method is used to predict the thermal behavior in the liquid oxygen tank with consideration of interface phase change. The numerical model is validated against the experimental results with relative error < 5%. The effect of the gas injection temperature on the tank t

Externally seeded schemes have offered a major leap in improving the longitudinal coherence of FELs in the EUV and soft X-ray range. The Echo Enabled Harmonic Generation (EEHG) technique creates bunching at wavelengths of a few nanometers in two stages of longitudinal phase space manipulation, each consisting of an energy modulator and a chicane. Compared to other seeding techniques, EEHG is less

Sugar beet pulp (SBP) is a by-product formed in large amounts during the production of refined sugar and is currently used as a low-cost feed for livestock. The dry SBP comprises largely three polysaccharides (75–85%), cellulose, hemicellulose and pectin, whose component sugars constitute potential valuable feedstock for producing building blocks for chemicals and materials. In the present study,

Background: Like most living organisms, the fruit fly Drosophila melanogaster exhibits strong and diverse behavioural reactions to light. Drosophila is a diurnal animal that displays both short- and long-term responses to light, important for, instance, in avoidance and light wavelength preference, regulation of eclosion, courtship, and activity, and provides an important model organism for unders

Peberholm is a constructed Danish island in the Øresund strait. It was primarily constructed by calcareous clay from the sea floor, and is traversed by a highway and a railway. Being constructed from material without a seed bank, Peberholm constituted a good opportunity to study primary succession in an anthropogenic context. In this study, data from a survey of the vascular plant community of Peb

AIMS/HYPOTHESIS: Obesity caused by overeating plays a pivotal role in the development of type 2 diabetes. However, it remains poorly understood how individual meal size differences are determined before the development of obesity. Here, we investigated the underlying mechanisms in determining spontaneous food intake in newly established Oikawa-Nagao Diabetes-Prone (ON-DP) and Diabetes-Resistant (O

Sitagliptin has been suggested as a treatment option for older adults with type 2 diabetes (T2D). However, no randomized controlled trial has been performed to evaluate the efficacy and safety of sitagliptin treatment in older Japanese patients with T2D. The STREAM study was a multicenter, open-label, randomized controlled trial. T2D outpatients aged 65-80 years with moderately controlled glycemic

Background: The number of people with a migration background and dementia is increasing in Europe. All patients with suspected dementia have the right to an appropriate cognitive assessment and correct diagnosis for optimal treatment and support. Rowland Universal Dementia Assessment Scale (RUDAS) cognitive screening instrument is less affected by language, culture, and educational background, and

Cancers require telomere maintenance mechanisms for unlimited replicative potential. They achieve this through TERT activation or alternative telomere lengthening associated with ATRX or DAXX loss. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, we dissect whole-genome sequencing data of over 2500 matched tumor-control samples from 36 different tumor types a

Cervical pathology may contribute to residual problems after surgery for ulnar nerve compression. We aimed to evaluate the presence of pathological conditions in spinal cord and cervical spinal nerve roots in patients surgically treated for ulnar nerve compression at elbow. In a cohort of patients, surgically treated for ulnar nerve compression at elbow, magnetic resonance images (MRI; performed 3

Bakgrund: Ungdomar går igenom många fysiska och psykiska förändringar och det uppstår svårigheter när ungdomar drabbas av en kronisk sjukdom som Diabetes mellitus typ 1. Studier visar att ungdomar har svårt att ta till sig information om sin sjukdom och har svårt att följa behandlingen. Sjuksköterskor som arbetar inom diabetesvården har en viktig roll i utbildningsprocessen. Syfte: Syftet med stud

The impact of different climate scenarios, drought, and water level management on the outflow water quality of peatlands has been investigated. A mesocosm experiment has been conducted within climate control chambers to simulate current (2016–2019 real-time) and future representative concentration pathway (RCP) climate scenarios (RCP 2.6, 4.5 and 8.5). To assess the efficiency of a management stra

The world of environmental microscopy provides the possibility to study and analyze transformations and reactions during realistic conditions to understand the processes better. We report on the design and development of a metal-organic chemical vapor deposition (MOCVD) system integrated with an environmental transmission electron microscope intended for real-time investigations of crystal growth.

This paper focuses on tech giants as active drivers of a phase of globalization characterized by growth in digital services trade combined with a general shift to intangible assets. By analysing how Google, Amazon and Microsoft organize their innovation activities, we show that they continuously monopolize knowledge while outsourcing innovation steps to other firms and research institutions. The p