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Ledningens vilja och avsikt : säkerhetspolicyer vid svenska förvaltningsmyndigheter

Alla organisationers ledningar vill ha en verksamhet som når upp till det som deras styrdokumenten vill förmedla. Ledningen har med sina säkerhetspolicyer visat sin vilja och avsikt med säkerhetatsarbetet och förväntar sig att dessa styrdokument ger resultat. Är det så enkelt? Kan ledningarna bli framgångsrikare gällande efterlevnad? Genom att ta reda på vad säkerhetspolicyer innehåller och om inn

Bicycle Traffic Volume Estimation Based on GPS Data

All the analytic methods for assessing the safety or comfort of bicyclists in urban area have as a common factor the number of bicycles that enter the system in a certain time interval or an estimate of that. The estimation of the average bicycle volume based on manual and automatic measurements is time-consuming and often require the use of expensive technology. The paper presents a method of est

Hypoxia-induced release, nuclear translocation, and signaling activity of a DLK1 intracellular fragment in glioma

Glioblastoma multiforme is characterized in part by severe hypoxia associated with tumor necrosis. The cellular response to hypoxia can influence several properties of tumor cells associated with aggressive tumor growth, including metabolic adaptations and tumor cell migration and invasion. Here, we found that Delta Like Non-Canonical Notch Ligand 1 (DLK1) expression was elevated as compared with

Comparison of the duration of hospital stay after laparoscopic or open distal pancreatectomy : randomized controlled trial

Background: Studies have suggested that laparoscopic distal pancreatectomy (LDP) is advantageous compared with open distal pancreatectomy (ODP) regarding hospital stay, blood loss and recovery. Only one randomized study is available, which showed enhanced functional recovery after LDP compared with ODP. Methods: Consecutive patients evaluated at a multidisciplinary tumour board and planned for sta

Achieving impact : Exploring the challenge of stakeholder engagement

There is an increasing expectation from research funding bodies that projects in working life and policy research (and other fields) should demonstrate clear and demonstrable impacts on policy and practice. In turn, many also argue that impact, beyond scientific impact, can be leveraged by stakeholder engagement. But what do we mean by stakeholder engagement in the conduct of working life research?

Overlapping morphological, immunohistochemical and genetic features of superficial CD34-positive fibroblastic tumor and PRDM10-rearranged soft tissue tumor

Superficial CD34-positive fibroblastic tumor (SCD34FT) is a recently recognized soft tissue tumor that is considered to be of borderline malignancy. The pathogenesis of this tumor remains incompletely understood, but it has been suggested that SCD34FT overlaps with tumors showing fusions involving the PRDM10 gene. Previous analyses of PRDM10-rearranged tumors have demonstrated that they have a dis

Selective Galectin-8N Ligands : The Design and Synthesis of Phthalazinone-d-Galactals

Ligand selectivity among the highly conserved galectins has been an ever-challenging objective. For galectin-8, a protein prevalent in both pathology and tissue distribution, we report phthalazinone-galactals that show excellent selectivity for the galectin-8N-terminal domain. A dissection of structure–activity relationships of the phthalazinone and an extensive molecular dynamics meta-analysis ac

Changing patterns of hierarchy within Swedish stepfamilies in the late 1700s

Like many other West European countries during the early modern period, Swedish society was structured by a variety of hierarchies and, in this context, the principle of filial deference, or the obedience and recognition children–young or adult–were expected to show their parents, was more or less absolute. These ideas of family hierarchy also influenced marriage laws and the formal rules of who w

From denial of facts to rationalization and avoidance : Ideology, needs, and gender predict the spectrum of climate denial

Climate denial takes many forms, ranging from outright denial of facts (literal denial), over distortion of facts (interpretive denial, e.g., denial of personal and global outcome severity), to the acknowledgement of facts but denial of their implications (implicatory denial, e.g., avoidance, denial of guilt, rationalization of own involvement). This study aimed at furthering the understanding of

Toward an Aesthetics by Algorithms—Palestinian Cyber and Digital Spaces at the Threshold of (In)visibility

This chapter explores how algorithms produce aesthetic forms and dystopian configurations across Palestinian cyber and digital spaces. Through surveillance and erasure, algorithms operate as infrastructures of (in)visibility across social media and digital maps. While serving the Israeli system of control by making Palestinian users and contents hyper-visible to surveillance, algorithms ultimately

Imagine a world without cancer

BACKGROUND: Since the "War on Cancer" was declared in 1971, the United States alone has expended some $300 billion on research, with a heavy focus on the role of genomics in anticancer therapy. Voluminous data have been collected and analyzed. However, in hindsight, any achievements made have not been realized in clinical practice in terms of overall survival or quality of life extended. This migh

Results of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy after early failure of adjuvant systemic chemotherapy

BACKGROUND AND OBJECTIVES: Failure to respond to systemic chemotherapy is considered an exclusion criterion by some institutions for treatment with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC). However, it is unknown if these patients benefit from HIPEC treatment. This study aimed to report on outcomes of HIPEC in patients who failed to respond to adjuvant systemic c

Search for a heavy charged boson in events with a charged lepton and missing transverse momentum from pp collisions at s =13 TeV with the ATLAS detector

A search for a heavy charged-boson resonance decaying into a charged lepton (electron or muon) and a neutrino is reported. A data sample of 139 fb-1 of proton-proton collisions at s=13 TeV collected with the ATLAS detector at the LHC during 2015-2018 is used in the search. The observed transverse mass distribution computed from the lepton and missing transverse momenta is consistent with the distr

Tourism and the Capitalocene : From Green Growth to Ecocide

Tourism makes substantial contributions to the Anthropocene. However, the Anthropocene is highly uneven over space and time reflecting the uneven processes of capital accumulation. As a result, the Anthropocene, and tourism's role within it, is best understood as a system of power, profit and re/production in the web of life, what is referred to as the capitalocene. In other words, it is the relat

Air Pollution and Urban Green Space : Evidence of Environmental Injustice in Adama, Ethiopia

While air pollution data in Ethiopia is limited, existing studies indicate high levels of both ambient and household air pollution; rapid urbanization also threatens the preservation of urban green spaces. In this study, environmental injustice, or the disproportionate burden of environmental exposures on persons of lower socioeconomic status (SES), was explored among women in Ethiopia using a mot

Gaming Activity and Possible Changes in Gaming Behavior Among Young People During the COVID-19 Pandemic : Cross-sectional Online Survey Study

Background: Young people's daily lives and social interactions changed remarkably during the COVID-19 pandemic as schools and cinemas closed, leisure activities were cancelled, and gatherings were regulated. Questions have been raised by the media, schools, policy makers, and research communities about the effect on young people's online behaviors. Objective: This cross-sectional study aimed to st

Higher Education and Research Policies : the current global agenda and implications for international cooperation

International collaboration is clearly a key priority in higher education andresearch (HER) policy and practice. The competition for students and excellentresearch and teaching staff is now a global one and this is reflected inthe increasing salience of phenomena such as the Shanghai and Times HigherEducation Rankings for monitoring the performance of HER institutions. Thischapter takes its point