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BACKGROUND/AIM: Circulating tumor DNA (ctDNA), which is shed from cancer cells into the bloodstream, offers a potential minimally invasive approach for cancer diagnosis and monitoring. This research aimed to assess the preoperative ctDNA levels in ovarian tumors patients' plasma and establish correlations with clinicopathological parameters and patient prognosis.PATIENTS AND METHODS: Tumor DNA was

Objectives: To define requirements that condition trust in artificial intelligence (AI) as clinical decision support in radiology from the perspective of various stakeholders and to explore ways to fulfil these requirements. Methods: Semi-structured interviews were conducted with twenty-five respondents—nineteen directly involved in the development, implementation, or use of AI applications in rad

Eight years since the UN’s agenda 2030, progress towards the Sustainable Development Goals (SDGs) has been poor. A crucial dimension is missing from current policy approaches: we urgently need to better understand the human inner skills and qualities necessary to work effectively together to meet ourcomplex challenges.Co-designed by thousands of experts, practitioners and scientists in response to

Urbanisation is accelerating across the globe, transforming landscapes, presenting organisms with novel challenges, shaping phenotypes and impacting fitness. Urban individuals are claimed to have duller carotenoid-based colouration, compared to their non-urban counterparts, the so-called ‘urban dullness’ phenomenon. However, at the intraspecific level, this generalisation is surprisingly inconsist

Socio-economic differences in mortality are among the most pervasive characteristics of Western societies. While the mortality gradient by income is well established for the period after 1970, knowledge about the origins of this gradient is still rudimentary. We analyse the association between income and cause-specific adult mortality during the period 1905–2014 in an area of southern Sweden, usin

OBJECTIVE: A somatic mutational hotspot in the SF3B1 gene was reported in lactotroph tumours. The aim of our study was to examine the prevalence of driver SF3B1 variants in a multicentre independent cohort of patients with lactotroph tumours and correlate with clinical data. DESIGN AND METHODS: This was a retrospective, multicentre study involving 282 patients with lactotroph tumours (including 6

Microbial contaminants are responsible for several infectious diseases, and they have been introduced as important potential food- and water-borne risk factors. They become a global burden due to their health and safety threats. In addition, their tendency to undergo mutations that result in antimicrobial resistance makes them difficult to treat. In this respect, rapid and reliable detection of mi

Access to healthcare can facilitate parents’ self-management of their children’s care. Healthcare access can be described as consisting of six dimensions: approachability, acceptability, affordability, availability, appropriateness, and aperture. The aim of this study was to analyse these dimensions of healthcare access experienced by parents caring for their children at home following paediatric

Background Lay online communication about health-related issues has in recent years largely been associated with the spread of misinformation and decreased trust in healthcare. Such communication has included claims about systemic side effects of the copper IUD. In Sweden, a social media group centered on this issue now gathers around 8,700 members. This study aimed to use the case of reported yet

In recent years, the need for affordable sustainable housing has increased. At the same time, there has been a gradual rising interest in compact living. With the mounting impacts of climate change, a new way of thinking is needed to develop more resilient and climate responsive ways of living that are compact, affordable, and climate-conscious. In response to this need, the idea of a ‘Z-Free Home

Common solutions for building energy-efficient buildings constitute e.g., double-glazed windows, airtight building envelopes and highly insulated walls. These solutions may improve the indoor environment/comfort but can also lead to adverse effect, e.g., mould at the surface of the construction components and consequently human health problems. With this study, a mould risk assessment including he

vNOTES hysterectomy is a scarless minimally invasive method with a vaginal approach to the abdominal cavity combined with endoscopic overview. Studies have shown that patients who underwent vNOTES hysterectomy had less pain and shorter hospital stay than after laparoscopic hysterectomy.

Background: Information and communication technology (ICT) provides one solution to meet increasing demands for occupational therapy for older adults. Aims/Objectives: To examine if and how municipality-based occupational therapists (OTs) include ICT in their work, and which factors are associated with use of occupational therapy at a distance. Material and Methods: Survey study including 167 OTs.

Carbonyl sulfide (COS) is a promising tracer for the estimation of terrestrial ecosystem gross primary production (GPP). However, understanding its non-GPP-related sources and sinks, e.g., anthropogenic sources and soil sources and sinks, is also critical to the success of the approach. Here we infer the regional sources and sinks of COS using continuous in situ mole fraction profile measurements

Purpose: A pilot study to identify bacterial biofilm in the lacrimal sacs of patients with chronic dacryocystitis, and in patients with epiphora but without discharge, using scanning electron microscopy. Methods: Five patients: two with nasolacrimal duct obstruction without dacryocystitis, and three with dacryocystitis refractory to antibiotics, underwent external dacryocystorhinostomy. One contro

Controlling NOx and CO2 emissions from heavy-duty diesel vehicles (HDDVs) is receiving increasing attention. Accurate measurement of HDDV NOx and CO2 emissions is the prerequisite for HDDV emission control. Vehicle emission regulations srecommend the measurement of NOx and CO2 emissions from vehicles using an emission analyzer, which is expensive and unsuitable to measure a large number of vehicle

Background: Psychological wellbeing is conceptualized as the full engagement and optimal performance in existential challenges of life. Our understanding of psychological wellbeing is important for us humans to survive, adapt, and thrive during the challenges of the 21st century. Hence, the measurement of psychological wellbeing is one cornerstone for the identification and treatment of both menta

Introduction: Our objective was to investigate the trajectories of anxiety, depression, emotional and social functioning in women with newly diagnosed vulvar cancer from the time of diagnosis to 12 months after treatment. A further aim was to identify risk factors for high levels of anxiety. Material and methods: PROVE (PROspective Vulvar Cancer Evaluation) is a nationwide longitudinal cohort stud