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Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors

Prostate-specific antigen (PSA) is one of the three most abundant prostatic-secreted proteins in human semen. It is a serine proteinase that, in its primary structure, manifests extensive similarities with that of the Arg-restricted glandular kallikrein-like proteinases. When isolated from semen by the addition of chromatography on aprotinin-Sepharose to a previously described procedure, PSA displ

Monte Carlo generators

I discuss some recent development of Monte Carlo event generators and point out some problems. Starting with the issue of combining matrix element generators and parton shower algorithms, I will continue with discussing the problems associated with describing small-x final states and discuss some recent model developments for describing multiple partonic scatterings and underlying events in hadron

Evolution effects in Z0 fragmentation into charmonium

In Z0 decay into prompt charmonium, i.e. charmonium not originating from B-meson decays, the most important contribution is expected to come from colour-octet mechanisms. However, previous fixed-order calculations of the colour-octet contribution contain large logarithms which, in a more complete treatment, should be resummed to all orders. We study this resummation by using a Monte Carlo QCD casc

Real-Time Calibration of Planar Laser Induced Fluorescence Air/Fuel-Ration Measurements in Combustion Environments Using in-situ Raman Scattering

A laser-based technique for recording absolute air-fuel ratio maps in a single-laser pulse in combustion devices, for instance, prior to ignition in internal combustion engines, is demonstrated. The method is based on an in situ pulse-to-pulse calibration of two-dimensional laser-induced fluorescence (LIF) images of relative fuel distributions by a point Raman measurement. A single excimer laser p

STED nanoscopy of Interfaces and Interactions between Nanostructure Arrays and Living Cells

STED Nanoscopy of Interfaces and Interactions between Nanostructure Arrays and Living Cells The specific arrangement of membrane lipids and proteins in a living cell at the interface to high-aspect ratio nanostructures (nanowires and nanostraws) is still unknown – as are the dynamic structural adaptations and molecular rearrangements of living cells in the vicinity of such nanostructures. Whether

Mechanistic Toxicology : Molecular interactions and underlying mechanisms of dendritic cell activation in skin sensitization

Allergic skin diseases caused by low molecular weight chemical compounds are a major health concern among the general population, especially in certain occupational groups. To limit exposure to such compounds, it is important that thorough risk assessments are performed before products reach the consumer market. Traditionally, such risk assessments have been based on animal tests, but due to sever

PIXE in complex analytical systems for atmospheric chemistry

A schematic mechanistic box model presenting processes in atmospheric chemical cycles is used to present the main research objectives. From this the main use of PIXE within atmospheric chemistry is discussed. An analytic system giving molecular composition is necessary to fully understand and quantify the chemical and physical pathways described in the model for different compounds. Combining PIXE

Is poor proprioception associated with worse movement quality of the knee in individuals with anterior cruciate ligament deficiency or reconstruction?

[Purpose] To investigate the association between proprioception and a knee medial to foot position during weight-bearing activities in patients with anterior cruciate ligament reconstruction and anterior cruciate ligament deficiency. [Participants and Methods] Thirty-eight patients with anterior cruciate ligament reconstruction and 13 patients with anterior cruciate ligament deficiency aged 18–40