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Epigenetics of methylmercury

Purpose of review: Methylmercury (MeHg) is neurotoxic at high levels and particularly affects the developing brain. One proposed mechanism of MeHg neurotoxicity is alteration of the epigenetic programming. In this review, we summarise the experimental and epidemiological literature on MeHg-associated epigenetic changes. Recent findings: Experimental and epidemiological studies have identified chan

Heparin-binding protein as a marker of ventriculostomy related infection and central nervous system inflammation in neuro-intensive care

Objective: Diagnosis of ventriculostomy related infections (VRI) in the neuro-intensive care unit remains challenging and current biomarkers lack adequate precision. The aim of this study was to explore the potential of Heparin-binding protein (HBP) in cerebrospinal fluid (CSF) as a diagnostic biomarker of VRI. Methods: All patients treated with an external ventricular drain (EVD) between January

Bathing into Belonging: An Exploration of International Students' encounters at the Swedish Sauna

This thesis is an ethnographic exploration of Swedish sauna practices as experienced by international students at Lund University. The research objective is to navigate experiences of belonging and community formation that occur in the sauna, but also highlights how experiences of outsiderness and exclusion come to the fore in this highly sensorial environment. The sauna is analysed as a microcosm

Högkvalificerad arbetskraft i rörelse - En kvalitativ studie om strategiska rekryteringsprocesser av högkvalificerad arbetskraftsinvandring

Denna kandidatuppsats redogör för hur internationella rekryteringsprocesser spelar roll för en ökad efterfrågan på specialiserad och högutbildad personal i en global marknad. Syftet är att titta på vilket behov den rörliga kompetensen täcker och studien fokuserar på varför företag ägnar sig åt internationell rekrytering. Undersökningen grundar sig på dels intervjuer med respondenter på en svensk s

First on-line application of the high-resolution spectroscopy laser ion source PI-LIST at ISOLDE

We report on the development, characterization, and first application of a specialized resonance ionization laser ion source for high-resolution spectroscopy applications below usual hot cavity Doppler broadening limitations, for on-line experiments at CERN-ISOLDE. The new PI-LIST ion source comprises perpendicular laser/atom beam interaction in a radio-frequency quadrupole unit directly downstrea

The role of the electroencephalogram and evoked potentials after cardiac arrest

Purpose of review: In comatose cardiac arrest survivors, the electroencephalogram (EEG) is the most widely used test to assess the severity of hypoxic-ischemic brain injury (HIBI) and guide antiseizure treatment. However, a wide variety of EEG patterns are described in literature. Moreover, the value of postarrest seizure treatment is uncertain. Absent N20 waves of short-latency somatosensory-evok

What is the point of method sections?

There are plenty of books and articles on research methods, but few discuss the nature and purpose of method sections in academic journals. Based on interviews with critical and interpretivist researchers, this short paper examines the nature and purpose of method sections in management and organization studies. We show how researchers make sense of, and struggle with, positivist expectations abou

Syndecan-4 is a maestro of gastric cancer cell invasion and communication that underscores poor survival

Gastric cancer is a dominating cause of cancer-associated mortality with limited therapeutic options. Here, we show that syndecan-4 (SDC4), a transmembrane proteoglycan, is highly expressed in intestinal subtype gastric tumors and that this signature associates with patient poor survival. Further, we mechanistically demonstrate that SDC4 is a master regulator of gastric cancer cell motility and in

A Study of Ayahuasca Documentary Film

This master thesis invites the reader to acquire and examine new evidence about an emerging and growing sub-genre type of documentary film called Ayahuasca documentary. This study bases its definition of the Ayahuasca documentary sub-genre on a current work in the progress catalogue of over 50 documentary films, two of which were selected as case studies. These films suggest a growing cultural int

Hydrogeological and economic analysis of a groundwater-based water supply system in rural Nepal

Access to safe drinking water and sanitation is a given standard and considered as basic human rights in urban areas and industrialized countries. However, 40 % of the world's population living in rural areas in developing countries lack access to safe drinking water. Many ongoing projects are focused on providing safe drinking water and sanitation in rural areas, including Hamro Paani. Hamro

Label-free detection of polystyrene nanoparticles in Daphnia magna using Raman confocal mapping

Micro- and nanoplastic pollution has emerged as a global environmental problem. Moreover, plastic particles are of increasing concern for human health. However, the detection of so-called nanoplastics in relevant biological compartments remains a challenge. Here we show that Raman confocal spectroscopy-microscopy can be deployed for the non-invasive detection of amine-functionalized and carboxy-fu

Effects of wing damage and moult gaps on vertebrate flight performance

Vertebrates capable of powered flight rely on wings, muscles that drive their flapping and sensory inputs to the brain allowing for control of the motor output. In birds, the wings are formed of arrangements of adjacent flight feathers (remiges), whereas the wings of bats consist of double-layered skin membrane stretched out between the forelimb skeleton, body and legs. Bird feathers become worn f

Tetratricopeptide-containing SMALL KERNEL 11 is essential for the assembly of cytochrome c oxidase in maize mitochondria

Assembly of the functional complexes of the mitochondrial respiratory chain requires sophisticated and efficient regulatory mechanisms. In plants, the subunit composition and assembly factors involved in the biogenesis of cytochrome c oxidase (complex IV) are substantially less defined than in mammals and yeast. In this study, we cloned maize (Zea mays) Small kernel 11 (Smk11) via map-based clonin

Reusable Takeaway Containers: Disposable to Durable - A feasibility study of transition towards reusable takeaway containers in Sweden

Ever growing environmental impact due to human activities has increased efforts globally to tackle the issues by promoting sustainable behavior. Similar efforts are also being made to handle the waste and litter problem of single-use takeaway food packaging. Sweden aims to reduce the impact of takeaway food packaging by introducing a directive to reduce consumption of single-use packaging and repl

The ST22 chronology for the Skytrain Ice Rise ice core - Part 2 : An age model to the last interglacial and disturbed deep stratigraphy

We present an age model for the 651g€¯m deep ice core from Skytrain Ice Rise, situated inland of the Ronne Ice Shelf, Antarctica. The top 2000 years have previously been dated using age markers interpolated through annual layer counting. Below this, we align the Skytrain core to the AICC2012 age model using tie points in the ice and air phase, and we apply the Paleochrono program to obtain the bes

A nutritional biomarker score of the Mediterranean diet and incident type 2 diabetes : Integrated analysis of data from the MedLey randomised controlled trial and the EPIC-InterAct case-cohort study

Background AU Self-reported: Pleaseconfirmthatallheadinglevelsarerepresentedcorrectly adherence to the Mediterranean diet has been: modestly inversely associated with incidence of type 2 diabetes (T2D) in cohort studies. There is uncertainty about the validity and magnitude of this association due to subjective reporting of diet. The association has not been evaluated using an objectively measured