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Thiopental pharmacokinetics in newborn infants: a case report of overdose.

Abstract Thiopental may be used for sedation before intubation in newborn infants. A boy, born at 33 weeks of gestation (gw); birth weight 2435 g, was prescribed thiopental 3 mg/kg before intubation. He developed temporary hypotension and oxygen desaturation, and remained unconscious for longer than expected with a suppressed electroencephalography for 48 h. Serum thiopental concentration was 82,

The probability of readmission within 30 days of hospital discharge is positively associated with inpatient bed occupancy at discharge - a retrospective cohort study.

Previous work has suggested that given a hospital's need to admit more patients from the emergency department (ED), high inpatient bed occupancy may encourage premature hospital discharges that favor the hospital's need for beds over patients' medical interests. We argue that the effects of such action would be measurable as a greater proportion of unplanned hospital readmissions among patients di

Från svartvit torftighet till en ocean av färgbilder

Artikeln beskriver utvecklingen och användningen av bilder bland utvecklingsstörda ungdomar. Under tre decennier har oerhört mycket hänt. Först på 80-talet insåg man att bilder kunde användas för att kommunicera med den som har svårt att läsa och skriva. Men det är först när ungdomarna börjar ta egna bilder för att dokumentera sin vardag som något annorlunda och stort inträffar.

Role of the innate immune system in host defence against bacterial infections: focus on the Toll-like receptors.

The innate immunity plays a critical role in host protection against pathogens and it relies amongst others on pattern recognition receptors such as the Toll-like receptors (TLRs) and the nucleotide-binding oligomerization domains proteins (NOD-like receptors, NLRs) to alert the immune system of the presence of invading bacteria. Since their recent discovery less than a decade ago, both TLRs and N

Tranexamic acid reduces blood loss in total hip replacement surgery.

Intraoperatively administered, tranexamic acid (TA) does not reduce bleeding in total hip replacement (THR). Therefore, its prophylactic use was attempted in the present study because this has been shown to be more effective in cardiac surgery. We investigated 40 patients undergoing THR in a prospective, randomized, double-blinded study. Twenty patients received TA given in two bolus doses of 10 m

Reduced postural differences between phobic postural vertigo patients and healthy subjects during a postural threat.

Phobic postural vertigo is characterized by subjective imbalance and dizziness while standing or walking, despite normal values for clinical balance tests. Patients with phobic postural vertigo exhibit an increased high-frequency sway in posturographic tests. Their postural sway, however, becomes similar to the sway of healthy subjects during difficult balance tasks. Posturographic recordings of 3

Predictive value of ultrasound assessed fetal head position in primiparous women with prolonged first stage of labor.

Objective: To examine how well ultrasound assessed occipitoposterior (OP) position or high sagittal (HS) position in primiparous women with a prolonged first stage of labor predicts a vaginal delivery and the duration of labor. Design: Prospective observational study. Setting. Stavanger University Hospital, a secondary referral center in Norway. Population. 105 primiparous women with prolonged f