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During normal cooking of meat, a class of mutagenic/carcinogenic compounds called heterocyclic amines is formed. Heterocyclic amines are rapidly absorbed and metabolised in the human body, and for estimation of the intake of heterocyclic amines, it is useful to determinate their levels in the urine. Blue Chitin columns were used for the extraction and purification of heterocyclic amines from urine
The complex [(IMesH2)(PPh2Cy)Cl2RuCHPh] was synthesised and shown to be an active catalyst in ring-closing metathesis of a diallylmalonate. Its phosphine exchange was investigated in C6D6 using magnetisation transfer 31P NMR spectroscopy and it was found to operate via a dissociative mechanism with k353 = 4.1 ± 0.9 s−1, ΔH‡ = 84 ± 10 kJ mol−1 and ΔS‡ = 4 ± 28 J mol−1 K−1.
Antibody microarray is a novel technology that will allow us to efficiently perform global proteome analysis. Performing rapid and multiplexed analysis on complex proteomes, such as human serum, targeting also low-abundant analytes will, however, place high demands upon the microarray design with respect to logistics, specificity and sensitivity. In this study, we have shown that non-purified affi
This paper discusses two feasibility studies of Genetic Programming (GP) to the field of control theory, GP being a method inspired from nature where the goal is to create a computer program automatically from high-level statements of problems' requirements. The first feasibility study derives from stability theory and deals with evolving a program that can solve discrete-time Lyapunov equations.
The difference between the resolvents of two selfadjoint extensions of a certain symmetric operator A is described by Krein's resolvent formula. We will prove an analog of Krein's formula in a general framework, apply it to extensions theory, and give a straightforward proof of Krein's formula including the case that A is not necessarily densely defined. We will also present a modification of Krei
This work was conducted to study the potential of molecularly imprinted polymers (MIPs) for the removal of oestradiol at trace concentrations (1 ppm - 1 ppb). An MIP synthesised with 17 beta-oestradiol as template was compared to non-imprinted polymers (NIP) synthesised under the same conditions but without template, a commercial C18 extraction phase and granulated activated carbon. At 1 ppb,oestr
A Saccharomyces cerevisiae screening strain was designed by combining multiple genetic modifications known to improve xylose utilization with the primary objective of enhancing xylose growth and fermentation in xylose isomerase (XI)-expressing strains. Strain TMB 3045 was obtained by expressing the XI gene from Thermus thermophilus in a strain in which the GRE3 gene coding for aldose reductase was
Calcitonin gene-related peptide and adrenomedullin belong to a structurally related neuropeptide family and are potent vasodilators expressed in the trigeminovascular system. The molecular identity of receptors for these proteins has only recently been elucidated. Central to functional binding of these neuropeptides is the G-protein-coupled receptor, the calcitonin receptor-like receptor (CRLR), W
Redox hydrogel-based micropatterned complex biosensor architectures, used as sensing chemistries in amperometric ethanol or glucose biosensors, were deposited on gold, graphite or glass. Well-localized immobilization of active hydrogels with variable compositions was achieved by dispensing 100 pl droplets of cocktails containing alcohol or glucose dehydrogenase, redox polymer (PVI(13)dmeOs) and cr
Formoterol administered by a dry-powder (DP) capsule inhaler was compared with a pressurized metered-dose inhaler (pMDI) with regard to bronchodilating and systemic effects. The study used a double-blind, crossover, double-dummy technique. Twelve patients with moderate reversible asthma in a stable phase were examined on two separate study days, and the inhalers were given in randomized order. Aft
Breast cancer is the most common form of malignancy affecting women in the Western world. Today, anticancer treatment can control primary breast tumors, but treatment and prevention of metastatic disease still represents a major challenge in the management of breast cancer patients. It has been shown that Wnt-5a plays an important role in breast cancer, since loss of that protein is associated wit
An 8-GHz beamforming transmitter IC has been designed in a 130-nm CMOS process. Two power amplifiers with independently controllable phase enable the beamforming. The phases are digitally controllable over the full 360° range, which is accomplished by binary weighting of quadrature phase signals in the power amplifiers. The quadrature phase signals are generated by a quadrature voltage controlled
Photoelectron spectra of Sr and Ca shallow core levels in Bi2Sr2CaCu2O81, (Bi2212) single crystals exhibit a strong attenuation effect because the photoelectron escape depth is very short in this material. This results may have a strong impact on the interpretation of ARPES and STM spectra near the Fermi level since it suggests the electronic states of planes other than CuO play a role in both tun
An extensive research program, dealing with fire growth on combustible wall lining materials, has been ongoing in Sweden over the last decade. Several lining materials were tested in bench-scale fire tests in order to derive basic material flammability parameters. The same materials were also tested in a full scale room test and a 1/3 scale room test for two different scenarios, A and B. Scenario
Objective: to investigate differences in regional tissue metabolism between open and endovascular aneurysm repair utilising a microdialysis technique. Materials: eight patients receiving endovascular stent grafts (STENT) and six patients undergoing open aortic surgery (OPEN) for abdominal aortic aneurysms were studied prospectively but non-randomised. Method: microdialysis catheters placed subcuta
Multiple Affiliations explores the autobiographical negotiations of memory and multilocality articulated by five (im)migrant women writers writing from, and being read (primarily) within the US. Texts as diverse as Korean-American Theresa Hak Kyung Cha's Dictée (1982), Polish (Jewish)-American Eva Hoffman's Lost in Translation: Life in a New Language (1989), Chinese-American Maxine Hong Kingston's
We establish existence and uniqueness of solutions in the anisotropic Sobolev space H^{1,1/2} to the two dimensional Navier-Stokes equations with source data in H^{-1,-1/2}. Our results give a new elementary proof for and extend some recent results by G. Grubb.
