Experiences from treatment-predictive KRAS testing; high mutation frequency in rectal cancers from females and concurrent mutations in the same tumor

BACKGROUND: KRAS mutations represent key alterations in colorectal cancer development and lead to constitutive EGFR signaling. Since EGFR inhibition represents a therapeutic strategy in advanced colorectal cancer, KRAS mutation analysis has quickly been introduced as a treatment-predictive test.METHODS: We used a real-time PCR based method to determine KRAS mutations in 136 colorectal cancers with

3 förslag för en bättre värld

Ett religiöst fredsbyggande - Nathan Söderblom och ekumenikens broar

Högpresterande betong: möjligheternas material

Grundlig beskrivning av sydösterbottnisk syntax

Lunds stifts landebok. D. 3, Tillkomst, innehåll, handskrifter samt register

Detection of fixations and smooth pursuit eye movements using local and global properties of the eye-tracking signal

Rörande "Hej!!!"

Kommentarer och bakgrund till faksimilutgåva av den lundensiska studentpublikationen "Hej!!!" (1892).

Review of Caesar. En biografi

Att klä sin rädsla i ord: berättelser om barnadödande demoner i antikens Grekland

Norms and Space. Understanding Public Space Regulation in the Tourist City

How are public spaces regulated in tourist cities? In this doctoral dissertation I seek to answer this question by exploring the intersections between urban tourism and public space regulation. I argue that public space regulation substantially differs from the tourist to the non-tourist zone. This thesis contradicts the common belief that public space regulation may vary from city to city, but re

Lund Archaeological Review 1996

Luce Irigaray, Sharing the World

Anders Ödmans bibliografi

An bibliography of the publications by Anders Ödman since 1975

Process measurement

Recension av "Ack om du vore här": 1800-talets folkliga brevkultur

Review of a book about the culture of letterwriting among ordinary people in the 19th century in Sweden.

Characteristics and outcome of brachial plexus birth palsy in neonates.

Aim: To relate pregnancy characteristics to extent and reversibility of brachial plexus birth palsy (BPBP) in neonates. Methods: Retrospective case-control study: newborns with a registered diagnosis of BPBP (n = 168) 1990-2005 were compared to data from a randomly selected control group (n = 1000). Characteristics were related to the level of injury, reversibility and outcome. Results: Among 51 8

Skandalhyllan: Full fart mot avgrunden

Nazistsymboler som har tagits i bruk av chefen för formel 1-cirkusen.

Näckens dödliga dop : manliga vattenväsen, död och förbjuden sexualitet i det tidigmoderna Sverige.

Accurate Calculation of the Isotope Shift and Hyperfine-structure In the Boron (b-ii) Line At 1362 Angstrom

An extensive multiconfiguration Hartree-Fock (MCHF) calculation of the isotope shift and hyperfine structure in the resonance line of B II at 1362 angstrom has been performed. The calculated B-11-B-10 isotope shift is 13.3 mangstrom with an estimated uncertainty of 1%. The calculated interaction constants A and B give a hyperfine structure splitting of less than 0.45 mangstrom for both isotopes. T