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‘From 'Security Risk' to Charter Rights – Gender, Sexuality and the Canadian Politics of Integration

Abstract in German Sogenannte sexuelle Minderheiten haben in Kanada grundlegende Veränderungen ihres rechtlichen und gesellschaftlichen Status erarbeitet. Zumindest bis in die 1960er Jahre galten schwule Männer auf Grund ihrer ‘Tendenzen’ als Gefahr für die nationale Sicherheit und als leichte Beute für (kommunistische) Erpressung. Gegenwärtig ermöglicht die kanadische Gesetzgebung die Ehe für gle

Mathematical Models and Algorithms for Wireless Network Design and Optimization

Optimization techniques always play an important role in designing high-performance wireless systems. This presented thesis studies a selected set of optimization problems for different kinds of wireless networks, making use of mathematical programming techniques to find optimal solutions and of efficient heuristics to find near-optimal solutions. The basic contribution of the thesis consists in a

Expression of GADS enhances FLT3-induced mitogenic signaling.

GADS is a member of a family of SH2 and SH3 domain-containing adaptors that functions in tyrosine kinase-mediated signaling cascades. Its expression is largely restricted to hematopoietic tissues and cell lines. Therefore, GADS is mainly involved in leukocyte-specific protein tyrosine kinase signaling. GADS is known to interact with tyrosine-phosphorylated SHC, BCR-ABL and KIT. The SH2 domain of G

Effects of gut microbiota on obesity and atherosclerosis via modulation of inflammation and lipid metabolism

Recent studies have revealed a close relationship between inflammatory and metabolic pathways, and inflammation is now recognized to have a major role in obesity and metabolic diseases such as insulin resistance and atherosclerosis. The human body is home to a large number of distinct microbial communities, with the densest population in the distal gut (the gut microbiota). Bacteria have long been

A Typology of Narratives of Social Inclusion and Exclusion: The Case of Bankrupt Entrepreneurs

On the macro level, bankruptcies are an intrinsic part of market economies and result in restructurings of companies and markets. On the micro level, bankrupt entrepreneurs are temporarily excluded from the market and forced to reorganize their understanding of the market. While some seek their way back to entrepreneurship, others decide to find other means of living which may result in drainage o