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Inferior survival for patients with malignant peripheral nerve sheath tumors defined by aberrant TP53

Malignant peripheral nerve sheath tumor is a rare and aggressive disease with poor treatment response, mainly affecting adolescents and young adults. Few molecular biomarkers are used in the management of this cancer type, and although TP53 is one of few recurrently mutated genes in malignant peripheral nerve sheath tumor, the mutation prevalence and the corresponding clinical value of the TP53 ne

Re-arthrodesis after primary ankle fusion : 134/1,716 cases from the Swedish Ankle Registry

Background and purpose — Arthrodesis is the most common treatment of severe ankle arthritis. Large studies on the occurrence of re-arthrodesis are few, especially with information in terms of risk. We used the National Swedish Ankle Registry to assess incidence and risk factors for re-arthrodesis. Patients and methods — In the Registry, we examined the occurrence of re-arthrodesis in 1,716 patient

Not so greedy : Enhanced subset exploration for nonrandomness detectors

Distinguishers and nonrandomness detectors are used to distinguish ciphertext from random data. In this paper, we focus on the construction of such devices using the maximum degree monomial test. This requires the selection of certain subsets of key and IV-bits of the cipher, and since this selection to a great extent affects the final outcome, it is important to make a good selection. We present

Protease-, pectinase-and amylase-producing bacteria from a Kenyan soda lake

Background: Alkaline enzymes are stable biocatalysts with potential applications in industrial technologies that offer high quality products. Objective: The growing demand for alkaline enzymes in industry has enhanced the search for microorganisms that produce these enzymes. Methods: Eighteen bacterial isolates from Lake Bogoria, Kenya, were screened for alkaline proteases, pectinases and amylases

Urban flood resilience – A multi-criteria index to integrate flood resilience into urban planning

Climate change and increasing urbanization pose huge challenges in managing urban planning for a sustainable future. Intense urbanization resulting in the so-called mega cites aggravates floods by increasing the amount of impermeable surfaces and modifying flow routes. Statistics show that flood disasters are one of the most significant in terms of damages and losses. Urbanization rates are increa

Low-Resolution Vision-at the Hub of Eye Evolution

Simple roles for photoreception are likely to have preceded more demanding ones such as vision. The driving force behind this evolution is the improvement and elaboration of animal behaviors using photoreceptor input. Because the basic role for all senses aimed at the external world is to guide behavior, we argue here that understanding this "behavioral drive" is essential for unraveling the evolu

The development and validation of a chemical kinetic model for anisole, a compound to represent biomass pyrolysis fuels

Lignocellulosic biomass is a promising alternative fuel source which can promote energy security, reduce greenhouse gas emissions, and minimize fuel consumption when paired with advanced combustion strategies. Pyrolysis is used to convert lignocellulosic biomass into a complex mixture of phenolic-rich species that can be used in a transportation fuel. Anisole (or methoxybenzene) can be used as a s

Digitalisering av kommunal socialtjänst : En empirisk studie av en organisation och profession i förändring

Inom projektet Digitalisering av socialt arbete (2016-2017) har Lupita Svensson, fil dr i socialt arbete vid Socialhögskolan, Lunds universitet, och Stefan Larsson, docent i teknik och social förändring vid institutionen för teknik och samhälle på LTH, Lunds universitet, tillsammans med socialtjänstens praktiker, beforskat arbetsprocesser och digitala mötesformer i socialtjänstens arbete och digit

Offentlighet i det digitala samhället : Vidareutnyttjande, sekretess och dataskydd

Digitalisering kan främja allmänhetens insyn och öka möjligheterna till vidareutnyttjande av information från den offentliga förvaltningen, men den kan också leda till nya risker för den personliga integriteten. Den här handboken tar ett helhetsgrepp om regleringen av allmänna handlingars offentlighet, vidareutnyttjande, sekretess och dataskydd i det digitala samhället. Medan reglerna om tillgång

Characterization of humic-like substances in Arctic aerosols

Humic‐like substances (HULIS) are a complex group of relatively high molecular weight organic compounds which contribute considerably to the mass of organic carbon (OC) and influence the light‐absorbing properties of aerosols. In this work, HULIS were investigated for the first time in the high‐Arctic atmosphere, focusing on the chemical characterization and mass contribution of HULIS to the total