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Direct and indirect impacts of climate and socio-economic change in Europe : a sensitivity analysis for key land- and water-based sectors

Integrated cross-sectoral impact assessments facilitate a comprehensive understanding of interdependencies and potential synergies, conflicts, and trade-offs between sectors under changing conditions. This paper presents a sensitivity analysis of a European integrated assessment model, the CLIMSAVE integrated assessment platform (IAP). The IAP incorporates important cross-sectoral linkages between

Contested expectations: Trump International Golf Links Scotland, polarised visions, and the making of the Menie Estate landscape as resource

In initiating the development of a large-scale golf resort in Aberdeenshire, Trump International Golf Links Scotland made a relatively unknown site central to Scottish planning debates. A stretch of land along the North Sea coast north of Aberdeen became linked to new possible futures. Part of the site developed consisted of moving sand dunes given environmental protection as a Site of Special Sci

Zinc Complexes of a Bioinspired Binucleating Ligand Platform - Equilibria in Solution and Structures in the Solid State

The zinc(II) coordination chemistry of the bioinspired bis(tetradentate) ligand 3,5-bis{bis[2-(1-methylimidazolyl)methyl]aminomethyl}pyrazole (L) was studied in detail both in solution and in the solid state. Six different species were determined in aqueous solution by means of potentiometry within the pH range 211, namely mononuclear [ZnH2L]4+, dinuclear [Zn2L]4+, [Zn2H1L]3+ and [Zn2H2L]2+, as we

Effects of sensory modality on learned mate preferences in female swordtails

Females often base their mate selection on multiple male traits. Different cues may be weighted differently in mating decisions, and play different roles such as indicating species identity or condition. The ontogeny of preferences for each cue can differ, which may offer a proximate explanation for the differential female evaluation of multimodal traits of males. We investigated whether female pr

A reduced model for the design of glass structures subjected to impact loads

A reduced finite element model for determining the maximum principal stress of a glass pane subjected to dynamic impact load is developed and compared to a full dynamic finite element model. The reduced model is based on the Rayleigh-Ritz method. The Ritz vectors used are determined by simple static load-cases. The model is applicable to centrically and eccentrically applied impact and to glass of

Incorporation of gene exchangeabilities improves the reproducibility of gene set rankings

Gene set-based analysis methods have recently gained increasing popularity for analysis of microarray data. Several studies have indicated that the results from such methods are more reproducible and more easily interpretable than the results from single gene-based methods. A new method for ranking gene sets with respect to their association with a given predictor or response, using a new framewor

Ultrafast Photovoltaic Response in Ferroelectric Nanolayers

We show that light drives large-amplitude structural changes in thin films of the prototypical ferroelectric PbTiO3 via direct coupling to its intrinsic photovoltaic response. Using time-resolved x-ray scattering to visualize atomic displacements on femtosecond time scales, photoinduced changes in the unit-cell tetragonality are observed. These are driven by the motion of photogenerated free charg

Prevalence of Back Problems in 1069 Adults With Idiopathic Scoliosis and 158 Adults Without Scoliosis.

Study Design. Multi-center case-control studyObjective. To investigate the prevalence of back problems in adults with idiopathic scoliosis.Summary of Background Data. Information on the prevalence of back problems in adults with idiopathic scoliosis is scarce, especially in untreated individuals, males and individuals with an age at onset of the scoliosis of less than 10 years.Methods. 1069 indivi

The epigenetic landscape of aneuploidy: constitutional mosaicism leading the way?

The role of structural genetic changes in human disease has received substantial attention in recent decades, but surprisingly little is known about numerical chromosomal abnormalities, even though they have been recognized since the days of Boveri as partaking in different cellular pathophysiological processes such as cancer and genomic disorders. The current knowledge of the genetic and epigenet

F-18-Flutemetamol Amyloid Imaging in Alzheimer Disease and Mild Cognitive Impairment A Phase 2 Trial

Objective: The most widely studied positron emission tomography ligand for in vivo P-amyloid imaging is C-11-Pittsburgh compound B (C-11-PIB). Its availability, however, is limited by the need for an on-site cyclotron. Validation of the F-18-labeled PIB derivative F-18-flutemetamol could significantly enhance access to this novel technology. Methods: Twenty-seven patients with early-stage clinical

Formation of CaCO3 Deposits on Hard Surfaces-Effect of Bulk Solution Conditions and Surface Properties

We have studied nucleation and crystal growth of calcium carbonate on hard surfaces, i.e. stainless steel and silica, at different temperatures, in relation to the corresponding bulk processes, using scanning electron microscopy (SEM), X-ray diffraction (XRD), and ellipsometry. In the bulk solution, a mixture of all three calcium carbonate crystalline polymorphs, calcite, aragonite, and vaterite,

Parsnip (Pastinaca sativa L.): Dietary fibre composition and physicochemical characterization of its homogenized suspensions

The dietary fibre composition in parsnip has been determined in the soluble and insoluble fraction, together with the physicochemical properties (morphology of particles, particle size distribution (PSD), volume fraction and rheological properties) of the parsnip suspensions at different paste concentration and degree of homogenization. The content of dietary fibre in parsnip was 30.4% of the dry

Multiple Scattering Suppression In Planar Laser Imaging Of Dense Sprays By Means Of Structured Illumination

A novel method to reduce the multiply scattered light contribution to images recorded with planar laser imaging is demonstrated. The technique, structured laser illumination planar imaging (SLIPI), is based on spatially modulated excitation light and is tested here within the dense region of a hollow-cone spray. The main idea is to use a laser sheet that is spatially modulated along the vertical d

First-Degree AV Block-An Entirely Benign Finding or a Potentially Curable Cause of Cardiac Disease?

First-degree atrioventricular (AV) block is a delay within the AV conduction system and is defined as a prolongation of the PR interval beyond the upper limit of what is considered normal (generally 0.20 s). Up until recently, first-degree AV block was considered an entirely benign condition. In fact, some complain that it is a misnomer since there is only delay and no actual block in the AV condu

Minimal Solvers for Unsynchronized TDOA Sensor Network Calibration

Calibration of network nodes using only time differences of arrival (TDOA) measurements opens up for interesting applications in wireless ad-hoc sensor networks, e.g. finding the positions of cell phones by only ambient sounds or radio. We present two novel approaches for the problem of self-calibration of network nodes using only TDOA when both receivers and transmitters are unsynchronized. We co

Support of Neuronal Growth Over Glial Growth and Guidance of Optic Nerve Axons by Vertical Nanowire Arrays.

Neural cultures are very useful in neuroscience, providing simpler and better controlled systems than the in vivo situation. Neural tissue contains two main cell types, neurons and glia, and interactions between these are essential for appropriate neuronal development. In neural cultures, glial cells tend to overgrow neurons, limiting the access to neuronal interrogation. There is therefore a pres

Clinically meaningful parameters of progression and long-term outcome of Parkinson disease: An international consensus statement.

Parkinson disease (PD) is associated with a clinical course of variable duration, severity, and a combination of motor and non-motor features. Recent PD research has focused primarily on etiology rather than clinical progression and long-term outcomes. For the PD patient, caregivers, and clinicians, information on expected clinical progression and long-term outcomes is of great importance. Today,