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Coxsackievirus A24 variant (CVA24v) is a major causative agent of acute hemorrhagic conjunctivitis outbreaks worldwide, yet the evolutionary and transmission dynamics of the virus remain unclear. To address this, we analyzed and compared the 3C and partial VP1 gene regions of CVA24v isolates obtained from five outbreaks in Cuba between 1986 and 2009 and strains isolated worldwide. Here we show tha
Cerebrospinal fluid (CSF) neurofilament light (NfL) concentration has reproducibly been shown to reflect neurodegeneration in brain disorders, including Alzheimer's disease (AD). NfL concentration in blood correlates with the corresponding CSF levels, but few studies have directly compared the reliability of these 2 markers in sporadic AD. Herein, we measured plasma and CSF concentrations of NfL i
(“Dissolved organic carbon leaching flux in a mixed agriculture and forest watershed in Rwanda” [1]). This article presents data of leached dissolved organic carbon (LDOC), stream water dissolved organic carbon), rainfall amount (Ra), rainfall intensity (Ri), rainfall soil storage (S), runoff (Q), and soil properties such as total organic carbon (TOC), total nitrogen (TN), cation exchange capacity
A growing body of consumer culture theory (CCT) research has pointed to the way that places are increasingly conceptualised and commodified as brands and consumption objects (Lichrou et al., 2008; Giovanardi et al., 2018). Research has explored consumers’ experiences with different kinds of spaces and places, including retail settings (e.g. Penaloza, 1998; Kozinets et al., 2004; Maclaran & Bro
OBJECTIVE: To compare the pain course between methotrexate (MTX)-refractory early rheumatoid arthritis (RA) patients randomised to infliximab (IFX) versus sulfasalazine+hydroxychloroquine (SSZ+HCQ).METHODS: The randomised, controlled, open-label SWEFOT (SWedish FarmacOTherapy) trial enrolled new-onset RA patients Oct 2002-Dec 2005. After 3 months on MTX, patients not reaching low disease activity
Introduction: Intracerebral hemorrhage (ICH) is the most serious adverse effect of oral anticoagulant (OAC) treatment. The effect of OAC reversal therapy on outcome is uncertain. We compared 90-day survival and functional outcome in patients with OAC-ICH who received OAC reversal therapy with those who did not. Methods: Data from The Swedish Stroke Register (Riksstroke) for all registered cases of
The K̄NN bound system, symbolically denoted as "K-pp", is the simplest K̄-nuclear bound system which has been widely discussed as a consequence of the strongly attractive K̄N interaction in I = 0 channels. Many theoretical works have pointed out the existence of the "K-pp" bound system, but the calculated properties such as the binding energy and the width spread out due to the uncertainty of the
The effect of gate-length variation on key transistor metrics for vertical nanowire p-type GaSb metal-oxide-semiconductor field-effect transistors (MOSFETs) are demonstrated using a gate-last process. The new fabrication method enables short gate-lengths (Lg = 40 nm) and allows for selective digital etching of the channel region. Extraction of material properties as well as contact resistance are The effect of gate-length variation on key transistor metrics for vertical nanowire p-type GaSb metal-oxide-semiconductor field-effect transistors (MOSFETs) are demonstrated using a gate-last process. The new fabrication method enables short gate-lengths (Lg = 40 nm) and allows for selective digital etching of the channel region. Extraction of material properties as well as contact resistance are
This article examines debates on historical theory in the journals Historisk tidskrift and Scandia between 1965, when theory is frequently said to have been introduced in Swedish historiography, and 2009. The study focuses on discussions on the epistemological concepts “theory”, “objectivity”, “relativism”, “truth”, and “neutrality”. It is shown that some historians initially perceived theory as a
Skäl för att överväga huruvida skäl för ett beslut, i frånvaron av bevis, bör berättiga beslutsfattande i särskilda omständigheter presenteras. Det föreslås att en distinktion mellan skäl och bevis baserad på deras tid-indexikala olikheter ger oss skäl att, i särskilda omständigheter, formulera beslutsfattandeprocedurer som inte, utöver skäl, också kräver bevis för premisserna för beslutet. Invänd
Introduction: The metabolic syndrome (MetS) is an adverse metabolic state composed of obesity, hyperglycemia/pre-diabetes, hypertension, and dyslipidemia. It substantially increases the risk of type 2 diabetes, cardiovascular disease (CVD) and mortality, and has a huge impact on public health. Area covered: The present review gives an update on the definition and prevalence of MetS, and its impact
The orthodox definition of hope suffers from an exclusion problem: it is unable to exclude subjects without hope. In fact, the orthodox definition even allows for despair to be falsely classified as hope. This problem suggests two basic desiderata for a successful analysis of hope: it should solve the exclusion problem, and it should have the resources to explain why, in a given situation, a subje
AIMS: We aimed to search for associations between cognitive test results with mortality and rehospitalization in a Swedish prospective heart failure (HF) patient cohort.METHODS AND RESULTS: Two hundred and eighty-one patients hospitalized for HF (mean age, 74 years; 32% women) were assessed using cognitive tests: Montreal Cognitive Assessment (MoCA), A Quick Test of Cognitive speed, Trail Making T
Recension av sociologen Roland Paulsens bok Tänk om - en studie i oro
