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Neurofilament light predicts worse nonmotor symptoms and depression in Parkinson's disease

Background: The identification of biomarkers that reflect worse progression of nonmotor symptoms (NMS) in Parkinson's disease (PD) is currently an unmet need. The main aim of this study was to investigate whether cerebrospinal fluid (CSF) and serum neurofilament light (NfL), measured at baseline or longitudinally, can be used to predict the progression of NMS in patients with PD. Methods: Baseline

An artificial intelligence-powered, patient-centric digital tool for self-management of chronic pain : a prospective, multicenter clinical trial

Objective: To investigate how a behavioral health, artificial intelligence (AI)-powered, digital self-management tool affects the daily functions in adults with chronic back and neck pain. Design: Eligible subjects were enrolled in a 12-week prospective, multicenter, single-arm, open-label study and instructed to use the digital coach daily. Primary outcome was a change in Patient-Reported Outcome

Constraining the eruption history of Rangitoto volcano, New Zealand, using palaeomagnetic data

New Zealand's largest city, Auckland, is situated within the basaltic Auckland Volcanic Field (AVF). Therefore, understanding the eruption history of the local volcanoes in the field is of great importance in order to assess future hazards that they may pose. Rangitoto is the youngest and largest volcano in the AVF, although the timing of the first eruption and the duration of the volcanic activit

Decarbonising industry : A places-of-work research agenda

Deep decarbonisation of extractive and foundational industries will involve widespread social and economic change. Research on previous industrial restructuring has demonstrated that resultant changes will be geographically uneven, especially without countervailing state intervention. Such change has been shown to matter for both the nature and location of work in those industries as well as for t

Depression and anxiety : A systematic review on comparing ecotherapy with cognitive behavioral therapy

The positive effects of nature on people's mental health are not only relevant for boosting their lifestyles, but could also play a role in the treatment of mental illness. To this end, the following systematic review investigates whether ecotherapy can achieve similar success as conventional cognitive-behavioral psychotherapy with regard to the treatment of depression and anxiety disorders, and w

Fugitive transformations of performance practice in landscapes of crisis

About the book:Theatre Institutions in Crisis examines how theatre in Europe is beset by a crisis on an institutional level and the pressing need for robust research into the complex configuration of factors at work that are leading to significant shifts in the way theatre is understood, organised, delivered, and received.Balme and Fisher bring together scholars from different disciplines and coun

Performance as Infrastructure and Institutional Unlearnings

About the book:"The Routledge Companion to Theatre and Politics is a volume of critical essays, provocations, and interventions on the most important questions faced by today's writers, critics, audiences, theatre and performance makers. Featuring texts written by scholars and artists who are diversely situated (geographically, culturally, politically, and institutionally), its multiple perspectiv

Destituent Spaces: Instituting as an Intervention

The Publication “Modeling Public Space(s) in Culture” is a continuation to the Conference Modelling Public Space(s) in Culture organised in Skopje in October 2017. The Conference aimed to offer a diverse thematic overview on “public space” as a physical location creating social ties and “public sphere” that contributes to the formation of public discourse. The publication explores the ideas brough

Collective Horizons: Rethinking the performative and the political (im)possibilities of being together

Invisible Committee, ‘the name given to a collective voice bent on denouncing contemporary cynicism and reality’ (described by one of the members of the anonymous group), published a text in 2007 that hypothesised the ‘imminent collapse of capitalist culture’ that would arise from new waves of social contestation. Under the title The Coming Insurrection the text (denounced as a manual for terroris

Ruptured Stages and the Dramaturgies of Debt and Time

About the book:Fourteen scholars who work on campus or in the theater address this issue of what it means to play offstage. With their individual definition of what “offstage” could mean, the results were, predictably, varied. They employed a variety of critical approaches to the question of what happens when the play moves into the audience or beyond the physical playhouse itself? What are the so

On Performing Publics

Fugitive publics do not need to be restored. They need to be conserved, which is to say moved, hidden, restarted with the same joke, the same story, always elsewhere than where the long arm of the creditor seeks them, conserved from restoration, beyond justice, beyond law. (Harney and Moten Citation2013: 63)Nearly ten years ago uprisings, occupations, self-organized platforms, demonstrations, publ

Haunting Dreams of a Wild Future OR What Children have to Teach us about Politics

In the last years we have witnessed an increased number of experimental performances that engage with children. Shows made in collaboration and/or performed by children. Children on stage, children as our tour guides through cities, children leading us though darkness. There are many ways to analyze this ‘interest’ including curatorial schemes encouraging participation, funding agendas, institutio