Basal cell carcinoma cells show low proliferation rates at the invasive front and a concordant upregulation of the cdk-inhibitor p16, limiting proliferative capacity. Little is known about the mechanisms of p16 regulation in normal and malignant cells apart from that many transcription factors such as Ets1, Ets2, SP1, SP3, JunB and the polycomb protein Bmi1 have the potential to induce or repress

The ability of the leucine-rich repeat (LRR) proteins biglycan, decorin and chondroadherin to interact with collagen VI and influence its assembly to supramolecular structures was studied by electron microscopy and surface plasmon resonance measurements in the BIAcore 2000 system. Biglycan showed a unique ability to organize collagen VI into extensive hexagonal-like networks over a time period of

We prove, under quite general assumptions, the global existence of classical solutions for quasilinear parabolic equations in bounded domains with homogeneous Dirichlet boundary conditions. The same results for weakly coupled reaction-diffusion systems are also given. 2000 Mathematics Subject Classification.

The computation of the electronic g tensor by two multireference methods is presented and applied to a selection of molecules including CN, BO, AIO, GaO, InO, ZnH, ZnF, O-2, H2O+, O-3(-), and H2CO+ (group A) as well as TiF3, CuCl42-, Cu(NH3)(4)(2+) and a series of d(1)-MOX4n- compounds, with M = V Cr, Mo, Tc, W, Re and X = F Cl, Br (group B). Two approaches are considered, namely, one in which spi

The workshop Reglermöte 85 was arranged during May 29-30 1985 at the Department of Automatic Control at Lund Institute of Technology. About 100 persons participated evenly divided between industry and universities. 18 papers were presented. Abstracts of the papers are given in the report.

Goodpasture disease (GP) is defined by the presence of anti-glomerular basement membrane (anti-GBM) antibodies and rapidly progressive glomerulonephritis. Besides anti-GBM, many patients with GP produce anti-neutrophil cytoplasmic antibodies (ANCA). For elucidation of the pathophysiologic significance of ANCA in this setting, epitope and antigen specificity of the anti-GBM antibodies and antigen s

Abstract is not available

The standard method used for tagging b-hadrons in the DELPHI experiment at the CERN LEP Collider is discussed in detail. The main ingredient of b-tagging is the impact parameters of tracks, which relies mostly on the vertex detector. Additional information, such as the mass of particles associated to a secondary vertex, significantly improves the selection efficiency and the background suppression

The purpose of this study was to investigate those parts of the care of hospitalized children that their parents perform, the nursing tasks the parents themselves felt they could manage and whether parents' and staff members' opinions coincided. A questionnaire was given to parents of children between one week and five years of age who were hospitalized at a pediatric surgical department during a

Popular Abstract in Swedish Den centrala punkten i avhandlingen är det faktum att redan under järnåldern har det varit möjligt att urskilja olika lokala särdrag i ett arkeologiskt material. För såväl gravar som hus har man varit noga med att följa det egna närområdets traditioner. Erfarenheterna från Halland visar att trots likartad ekonomi har husen men också det synliga gravskicket varierat betyThe aim of the dissertation is to elucidate Iron Age settlement in southern Halland from two angles: (1) the evidence of antiquities (graves), ground finds of metal and rock, and place-names; (2) the information conveyed by investigations in settlement archaeology. The combined study of graves, ground finds, and place-names shows that the image of southern Halland in the Iron Age differs depending

Aims: This study examined whether middle-aged men exhibiting markers of early ageing showed a different pattern of social factors, lifestyle, and biological variables compared with controls, and whether early ageing was associated with an increased mortality risk. Subjects and methods: We used a subgroup of 5,722 middle-aged men (mean age 47 years), investigated twice, from the Malmö Preventive Pr

Lipids from spinach thylakoids were extracted with chloroform/methanol and separated from pigments in a single chromatographic step run at 5 degrees C using silicic acid adjusted to pH 8. The isolated lipid fraction contained essentially the same amounts of individual lipids as in the initial extract. It contained less than 0.1% of the initial chlorophylls and carotenoids.

Popular Abstract in Swedish "Varje text hur utan värde än / blir lysande som död och sol och stränder, / när jag spelar er förväntan, / detta ojämförligt rika instrument" Så säger Harlequin till sin publik i Paul Anderssons Berättarna från 1955. Spelar med publikens förväntan gör också diktverkets upphovsman. I diktens spegel iscensätts den författargestalt som hade blivit ett fenomen i den litteBeing one of the central poets in the Swedish neo-Romantic movement of the early 1950's, Paul Andersson (1930-1976) was surrounded by a bright authorial aura even before he published his first poems at the age of 21. In 1953, Andersson's reputation became nationwide when the influential poet and critic Karl Vennberg declared him to be a genius. Three years later, Andersson had published his last b

Doppler shift attenuation lifetime measurements have been carried out for the 3qp and isomeric rotational bands in Y-83 using the reaction (Ni(Si,3p))-Ni-58-Si-28. While the transitional quadrupole moments in the 3qp bands are slightly lower than in the 1 qp bands, we found evidence for a strong reduction in \Q(t)\ for the isomeric band.

The dynamics of visible-to-ultraviolet upconversion in YAlO3: 1% Er3+ crystal has been investigated using the time-resolved laser spectroscopy when the sample was excited into the S-4(3/2) multiplets. It is found that the upconverted luminescence is produced by energy-transfer upconversion or by excited-state absorption depending on the excitation wavelength. The dependence of upconverted luminesc

The intracellular signal cascade transducing muscarinic-receptor-stimulation to gene expression was investigated in human neuroblastoma SH-SY5Y cells. Naive and ethanol-exposed SH-SU5Y cells were stimulated with carbachol (CCh) and inositol 1,4-5-trisphosphate (IP3), 1,2-diacylglycerol (DAG), and c-fos mRNA levels were analyzed using a radioreceptor assay (IP3) thin-layer chromatography (DAG) and

Background: Current models of group and team development generally favour a linear progressive developmental pattern (Tuckman-Wheelan), taking for granted that all groups move from relative irrationality and inefficency to rationality and efficiency through learning or maturation in sequential stages. Aims: (i) To question the generality of the linear progressive models of group development, (ii)