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Yttrande för remissen : Vissa åtgärder för stärkt återvändandeverksamhet och utlänningskontroll (SOU 2024:80) Ju2024/02572

Samhällsvetenskapliga fakulteten är kritiska till utredningens förslag med undantag för enstaka delar där vi inte har några synpunkter, samt något förslag som vi tillstyrker. Samhällsvetenskapliga fakulteten avråder från att gå vidare med fler skarpa lagförslag som tar samhällsutvecklingen i en riktning där människor håller sig undan myndighetskontakter, och som leder till förtroendeskador gentemo

In Operando Locally-Resolved Photophysics in Perovskite Solar Cells by Correlation Clustering Imaging

The instability of metal halide perovskites limits the commercialization of solar cells despite their impressive efficiencies. This instability, driven by photo-induced ion migration, leads to material restructuring, defect formation, degradation, and defect healing. However, these same “unwanted” properties enable to propose Correlation Clustering Imaging (CLIM), a technique that detects local ph

Evolved and Plastic Gene Expression in Adaptation of a Specialist Fly to a Novel Niche

How gene expression evolves to enable divergent ecological adaptation and how changes in gene expression relate to genomic architecture are pressing questions for understanding the mechanisms enabling adaptation and ecological speciation. Furthermore, how plasticity in gene expression can both contribute to and be affected by the process of ecological adaptation is crucial to understanding gene ex

Difficult cannulation during endoscopic retrograde cholangiopancreatography—needle-knife precut versus transpancreatic sphincterotomy on the basis of successful cannulation and adverse events

Background: When cannulation is challenging during endoscopic retrograde cholangiopancreatography (ERCP), and the standard guidewire technique with sphincterotomy is unsuccessful, alternative cannulation techniques can be used to access the biliary tree. The purpose of this study was to compare the incidence of adverse events and cannulation success rates between transpancreatic sphincterotomy (TP

Pluripotent stem-cell-derived therapies in clinical trial : A 2025 update

Since the first derivation of human pluripotent stem cells (hPSCs) 27 years ago, technologies to control their differentiation and manufacturing have advanced immensely, enabling increasing numbers of clinical trials with hPSC-derived products. Here, we revew the landscape of interventional hPSC trials worldwide, highlighting available data on clinical safety and efficacy. As of December 2024, we

ESTRO/EANO recommendation on reirradiation of glioblastoma

Background and Purpose: Although reirradiation of glioblastoma has a long history of clinical practice, guidance on how to perform it in the context of recent technological advances, modern imaging modalities or systemic therapy is scarce. This joint ESTRO/EANO guideline aims to collect the existing evidence to produce recommendations for safe reirradiation of glioblastoma. Methods: The basis of t

Neuronal CD59 isoforms IRIS-1 and IRIS-2 as regulators of neurotransmitter release with implications for Alzheimer’s disease

We have previously demonstrated that the intracellular, non-GPI anchored CD59 isoforms IRIS-1 and IRIS-2 (Isoforms Rescuing Insulin Secretion 1 and 2) are necessary for insulin secretion from pancreatic β-cells. While investigating their expression across human tissues, we identified IRIS-1 and IRIS-2 mRNA in the human brain, though their protein expression and function remained unclear. This stud

Pulmonary exposure to renewable diesel exhaust particles alters protein expression and toxicity profiles in bronchoalveolar lavage fluid and plasma of mice

Exposure to diesel exhaust is associated with increased risk of cardiovascular and lung disease. Substituting petroleum diesel with renewable diesel can alter emission properties but the potential health effects remain unclear. This study aimed to explore toxicity and underlying mechanisms of diesel exhaust from renewable fuels. Using proximity extension assay (Olink), 92 proteins linked to inflam

Semi-standardized evaluation of extraprostatic extension and seminal vesicle invasion with [18F]PSMA-1007 PET/CT : a comparison to MRI using histopathology as reference

Background: Positron emission tomography/computed tomography (PET/CT) with prostate specific membrane antigen ligands (PSMA) is established for use in primary staging of prostate cancer to screen for metastases. It has also shown promise in local tumor staging, including detection of extraprostatic extension (EPE) and seminal vesicle invasion (SVI). Previous studies have shown high heterogeneity i

Precarious employment, strenuous working conditions and the long-term risk of diagnosed chronic musculoskeletal disorders

Objectives To investigate the effect of precarious employment (PE) on the risk of diagnosed chronic musculoskeletal disorders (MSDs) among Swedish workers in occupations with strenuous working conditions. Methods This nationwide register-based cohort study included workers registered as living in Sweden in 2005, aged 21-60 at the 2010 baseline. Three samples were included: workers with high biomec

T2 Podcast: Talking Transformations : season 2, episode 1-5

Research shows conversations matter - both for learning and inspiring action. In this podcast collection, we are 'Talking Transformations' with thought leaders from government, industry, and academia. Our mission is to discuss current trends in science, technology, governance, and behaviours to transform our society and economy towards sustainability. In this podcast mini-series, season 2, we talk

Resurrected analysis : Navigating time between two environmental projects in Finland

This paper considers the ways in which research projects linger beyond their ‘official’ endings, and how to deal with this. Building on conversations in human geography and related disciplines on slow research, performed endings, and the practical and socio-political complexities of data storage and analysis over time, I relate some experiences with my research on the Finnish Saimaa Ringed Seal, w

Pathogenic KIAA0586/TALPID3 variants are associated with defects in primary and motile cilia

Pathogenic variants in KIAA0586/TALPID3 are associated with the ciliopathy Joubert syndrome (JS). We report individuals with KIAA0586/TALPID3 variants affected by primary and motile cilia defects leading to JS and chronic destructive airway disease. DNA variants were detected in three families by sequencing. In two unrelated families, a deep-intronic variant (KIAA0586/TALPID3:c.3990 + 3186G>A) act

Living in a bubble with profound difficulties—parents' experiences of extremely preterm survivors

Aim: To analyse the challenges faced by parents of extremely preterm infants born before 24 weeks of gestation and the potential buffering effect of perceived resources on the family's health continuum. Methods: The qualitative data were obtained from 70 parents of 70 infants born before 24 weeks of gestation, through open-ended questions in a survey. An inductive content analysis was conducted to

Are quick equivalent doses realistic? Testing range-finder luminescence dating for water-lain and postglacial flooding sediments in NE Poland

Raw sediment samples which are without prior lengthy laboratory preparation can be used to obtain a rough but rapid estimate of the luminescence equivalent dose, and thus of the relative age of the sediment. In this study, we tested this range-finder method on clastic sediments in NE Poland for the first time, with special focus on Pleistocene meltwater sediments generated by highly energetic glac

Factor Models With Sparse Vector Autoregressive Idiosyncratic Components

We reconcile dense and sparse modelling by exploiting the positive aspects of both. We employ a high-dimensional, approximate static factor model and assume the idiosyncratic term follows a sparse vector autoregressive model (VAR). The estimation is articulated in two steps: (i) factors and loadings are estimated via principal component analysis (PCA); (ii) a sparse VAR is estimated via the lasso

FABLE Scenathon 2023 Pathways for food and land-use systems in Sweden

Our food and land-use systems are critical for staying within our planetary boundaries and the Earth’s system resilience. Among the six Transformations required to achieve the Sustainable Development Goals (SDGs), the fourth Transformation—focusing on food, land, and water—is crucial. This Transformation is key to achieving SDG 2 (Zero Hunger), SDG 6 (Clean Water and Sanitation), SDG 12 (Responsib

Do directed and non-directed oocyte donors differ regarding their motives, ambivalence, satisfaction and openness about donating?

Research question: Do directed oocyte donors differ from non-directed identity-release oocyte donors regarding pre-donation motives and ambivalence, and post-donation satisfaction and openness? Design: The study is part of the longitudinal Swedish Study on Gamete Donation where consecutive samples of identity-release gamete donors at seven Swedish University Hospitals were approached during a 3-ye