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Host Imprints on Bacterial Genomes-Rapid, Divergent Evolution in Individual Patients

Bacteria lose or gain genetic material and through selection, new variants become fixed in the population. Here we provide the first, genome-wide example of a single bacterial strain's evolution in different deliberately colonized patients and the surprising insight that hosts appear to personalize their microflora. By first obtaining the complete genome sequence of the prototype asymptomatic bact

Androgen receptor polymorphism dependent variation in prostate specific antigen concentrations of European men.

Background Androgens acting via the androgen receptor (AR) stimulate production of prostate specific antigen (PSA), which is a clinical marker of prostate cancer (PCa). Since genetic variants in the AR may have a significant impact on the risk of being diagnosed with PCa, the aim was to investigate if AR-variants were associated with the risk of having PSA above clinically used cut-off thresholds

Search for supersymmetry at root 8=8 TeV in final states with jets and two same-sign leptons or three leptons with the ATLAS detector

A search for strongly produced supersymmetric particles is conducted using signatures involving multiple energetic jets and either two isolated leptons (e or mu) with the same electric charge, or at least three isolated leptons. The search also utilises jets originating from b-quarks, missing transverse momentum and other observables to extend its sensitivity. The analysis uses a data sample corre

Superhydrophobic polymeric coatings produced by rapid expansion of supercritical solutions combined with electrostatic deposition (RESS-ED)

In this paper we present a method to produce superhydrophobic polymeric coatings by combining the rapid expansion of supercritical solutions (RESS) with electrostatic deposition (ED). A copolymer, poly(vinyl acetate)-poly(vinyl pivalate) was dissolved in a mixture of supercritical carbon dioxide and acetone and sprayed through a nozzle with an applied voltage of 8 kV onto a surface placed on a ear

Improving densely deployed wireless network performance in unlicensed spectrum through hidden-node aware channel assignment

It is well known that a wireless local area network (WLAN) based on the IEEE 802.11 standard suffers from interference and scalability problems due to the limited number of non-overlapping channels. In order to mitigate the interference problem, channel assignment algorithms has been a popular research topic in recent years. It has been shown that such algorithms can greatly reduce the interferenc

Adult weight change and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition

Aim: Weight change during adult life may reflect metabolic changes and influence colorectal cancer (CRC) development, but such role is not well established. We aimed to explore the association between adult weight change (from age 20 to 50) and CRC risk. In particular, we investigated differences according to colon and rectal cancer, sex and measures of attained adiposity. Methods: We included 201

Monitoring Hepatitis C Infection in a Major Swedish Nephrology Unit and Molecular Resolution of a New Case of Nosocomial Transmission

Hepatitis C virus (HCV) infection is a frequent problem in hemodialysis units. The prevalence and incidence of HCV infection over a decade were studied in a nephrology unit affected by previous nosocomial HCV transmission. The HCV non-structural 5B protein gene was sequenced to achieve phylogenetic analysis of a new (incident) case of infection. Proportions of patients who were and were not infect

Pore Condensation in Glycerol Dehydration

Pore condensation followed by polymerization is proposed as an explanatory model of several observations reported in the literature regarding the dehydration of glycerol to acrolein. The major conclusion is that glycerol pore condensation in the micro- and mesopores, followed by polymerization in the pores, play a role in catalyst deactivation.

STS-inspired design to meet the challenges of modern ageing. Welfare technology as a tool to promote user driven innovations or another way to keep older users hostage?

Abstract Older technology users and their integration into IT society have been on the research agenda since digitalization took off. Given the attempts to develop user-driven design, it is surprising that the appearance of technologies older people are provided with, or are the target group for, have not progressed. Now another political agenda, coined as “welfare technology”, is being launched i

Slow light for deep tissue imaging with ultrasound modulation

Slow light has been extensively studied for applications ranging from optical delay lines to single photon quantum storage. Here, we show that the time delay of slow-light significantly improves the performance of the narrowband spectral filters needed to optically detect ultrasound from deep inside highly scattering tissue. We demonstrate this capability with a 9 cm thick tissue phantom, having 1

Association’s between wage system and risk factors for musculoskeletal disorders among construction workers

Abstract in UndeterminedPiece rate and performance based wage systems are common in the construction industry. Construction workers are known to have an increased risk of pain and musculoskeletal disorders (MSD). In this cross-sectional questionnaire study, we examined the association between wage system and (1) physical exertion, (2) time pressure, (3) pain, and (4) fatigue. The participants comp

Tip-Enhanced Ultrasensitive Stokes and Anti-Stokes Raman Spectroscopy in High Vacuum

We report ultrasensitive Stokes and anti-Stokes Raman spectra of 1,2-benzenedithiol monolayer on Ag film with home-made high-vacuum tip-enhanced Raman spectroscopy (HV-TERS) system. Raman peaks that were orginally very weak were observed experimentally and assigned theoretically. The local temperature was obtained based on the observed Stokes and anti-Stokes HV-TERS spectra.

A test method to assess the frost resistance of concrete at the waterline of hydraulic structures

Superficial damage, similar in appearance to salt scaling of concrete, has been observed at the waterline of hydraulic structures, such as hydro power structures, bridge columns, canals and harbours. Progressive damage to the concrete surface results in exposure of coarse aggregate. Deterioration rates of about 1 mm per year have been observed in some cases. A laboratory test method was developed

Nonlinear compartmental model of F-18-choline

Introduction: This work develops a compartmental model of F-18-choline in order to evaluate its biokinetics and so to describe the temporal variation of the radiopharmaceuticals' uptake in and clearance from organs and tissues. Methods: Ten patients were considered in this study. A commercially available tool for compartmental analysis (SAAM II) was used to model the values of activity concentrati

Free to Trade? Commission Autonomy in Economic Partnership Agreement Negotiations

In this article, we suggest that the degree of (dis)unity - both between the member states (MS) in the Council and within the Commission - is a key factor in affecting the balance between Commission autonomy and MS control in international trade negotiations. We shed empirical light on this issue, and on the relative influence of MS and the Commission in general, through a case study of the Econom

Sensitization to palladium in Europe

BackgroundRecently, sodium tetrachloropalladate (Na2PdCl4) was found to be a more sensitive palladium patch test allergen than palladium dichloride (PdCl2). ObjectivesTo determine the optimal test concentration of Na2PdCl4, to evaluate the prevalence of palladium sensitization with Na2PdCl4 and PdCl2, and to compare the results with nickel sensitization in a European multicentre study. Materials a