Galectin-9 consists of two peptide-linked carbohydrate recognition domains (CRDs), but alternative splicing and proteolytic processing can give rise to multiple galectin-9 isoforms. Some of these consist of a single CRD and can exert different functions in cell biology. Here, we explored the role of these galectin-9 isoforms in endothelial cell function and angiogenesis. For this, we compared the

Objective: To describe the development and evaluation of the content and face validity and test-retest reliability of a disease-specific questionnaire that measures patient-reported outcomes and experiences for the Swedish National Diabetes Register for adult patients who have type 1 or type 2 diabetes. Methods: In this methodological study, a questionnaire was developed over four phases using an

BACKGROUND: Increased somatostatin plasma concentration has been found in patients with vascular dementia. However, it is unknown whether or not somatostatin levels may predict dementia development in the general population. To this end, we sought to assess the association of circulating N-terminal prosomatostatin (NT-proSST) with incident dementia among community-dwelling older adults.METHODS: In

Soil disturbance from stump extraction and site preparation will initially lead to a reduction in carbon dioxide emissions from the soil. This is one result achieved from a series of new experiments established throughout Sweden and is contrasting to what was previously assumed. After one year however, this initial reduction had disappeared and emissions were around the same level for bothdisturbe

The active membership of Swedish trade unions and union confederations is recorded year for year (women union members in a separate column). The organizational history of the individual trade unions and confederations is also shown.

In this paper, we shall be concerned with geometric functionals and excursion probabilities for some nonlinear transforms evaluated on Fourier components of spherical random fields. In particular, we consider both random spherical harmonics and their smoothed averages, which can be viewed as random wavelet coefficients in the continuous case. For such fields, we consider smoothed polynomial transf

Recently it has become clear that interferon (IFN)-α, a type I interferon produced rapidly in response to infection, not only plays a key role in innate immunity, but also promotes adaptive immune responses by influencing the production or function of other cytokines. During infections IFN-α fosters the production of IL-15, which plays a pivotal role in the development, survival and function of NK

Purpose: Catquest-9SF is a 9-item visual disability questionnaire developed for evaluating patient-reported outcome measures after cataract surgery. The aim of this study was to use Rasch analysis to determine the responsiveness of Catquest-9SF for corneal transplant patients. Methods: Patients who underwent corneal transplantation primarily to improve vision were included. One group (n = 199) com

We studied the brittle-ductile transition in three porous carbonates, Indiana, USA, Majella, Italy, and Leitha, Austria, with porosity ranging between 16 and 31%. A series of triaxial experiments were performed at room temperature, constant strain rate, and at effective pressures ranging from 5 to 150 MPa. Several sets of X-ray Tomography images were acquired before and after deformation. 3D digit

Background: New or increased impairments may develop several decades after an acute poliomyelitis infection. These new symptoms, commonly referred to as late effects of polio (LEoP), are characterised by muscular weakness and fatigue, generalised fatigue, pain at rest or during activities and cold intolerance. Growing older with LEoP may lead to increased activity limitations and participation res

The paper analyses the hegemony of the growth paradigm through the example of its naturalisation in capitalist production and consumption relations. Applying a combination of theoretical elements from the Marxian tradition, the Regulation approach and Bourdieusian sociology, emphasis is placed on how the growth imperative is reflected in people’s minds and bodies. It becomes hegemonic because it a

The Compare-Acute trial demonstrates the relative safety and utility of performing multivessel FFR to examine the significance of non-culprit lesions during primary PCI. Patients who had an FFR-guided PCI strategy for non-culprit lesions during the index hospitalisation had fewer adverse cardiovascular events, essentially unplanned revascularisations, as compared to patients who were treated for t

The main aim was to assess the impact of mastitis on technical and economic results of a dairy herd under current Swedish farming conditions. The second aim was to investigate the effects obtained by withdrawing milk with high somatic cell count (SCC). A dynamic and stochastic simulation model, SimHerd, was used to study the effects of mastitis in a herd with 150 cows. Results given the initial in

BACKGROUND: Serum cathepsin B activity has been considered a potential marker of tumor progression. We previously demonstrated that low-frequency electromagnetic stimulation (LF EMS), called bioresonance therapy (BRT), may both accelerate and inhibit the growth of transplantable hepatoma (Morris type 5123D), including total tumor regression. The aim of this study was to assess serum cathepsin acti

This chapter examines the legal and critical judgments passed on Percy Bysshe Shelley’s first major poem, Queen Mab (1813). It argues that such judgments played an instrumental role in the shaping by Victorian critics not just of Shelley’s status as a canonical author, but also of the wider cultural phenomenon which we call Romanticism. Central to this process, in judging Queen Mab, were questions

Improved water, sanitation and hygiene (WASH) are significant in preventing diarrhea morbidity and mortality caused by protozoa in low- and middle-income countries. Due to the intimate and complex relationships between the different WASH components, it is often necessary to improve not just one but all of these components to have sustainable results. The objective of this paper was to review the c