Populärvetenskaplig sammanfattning1,7 miljoner nya fall av bröstcancer diagnosticeras årligen i världen. Bröstcancer är kvinnans vanligaste tumörsjukdom och i västvärlden samt Sverige kommer var åttonde till var nionde kvinna att insjukna under sin livstid. Överlevnaden efter bröstcancer är bland de högsta i världen i Sverige, med femårsöverlevnad på cirka 90%. För de kvinnor som diagnosticeras i Most patients with breast cancer present with low-risk tumors, node-negative disease, and excellent prognosis. For these patients, routine axillary nodal staging by sentinel lymph node biopsy (SLNB) has no therapeutic benefit. For patients with limited sentinel lymph node metastasis, completion axillary nodal dissection is controversial. Furthermore, those with heavy-burden metastasis could benefi

AIM: This study investigated time trend and regional disparities in hospitalisations due to osteoarthritis (OA) among people aged ≥20 years in Sweden from 1998 through 2015.METHODS: National and regional data on hospital admissions with a primary diagnosis of OA were collected from the National Patient Register. The absolute and relative regional disparities were assessed using the absolute weight

This letter presents a wideband cross-slot antenna (CSA) with inductor loadings for dual polarization. The effects of the ground size on the impedance are investigated. To achieve a compact size, a very small ground having the same hypotenuse length as the slot is used. The inductor loadings are used at both ends of the slot to reduce the size further. Simulated results show that the loaded induct

A model of (Formula presented.) atmospheric transport in vegetated canopies is tested against measurements of the flow, as well as (Formula presented.) concentrations at the Norunda research station located inside a mixed pine–spruce forest. We present the results of simulations of wind-speed profiles and (Formula presented.) concentrations inside and above the forest canopy with a one-dimensional

The article tells the story of the rise and fall of the organic store Yggdrasill in Iceland. That story features humble founders, caring customers, dedicated staff, as well as anonymous investment funds, and it describes the conversion of organics from a niche market to mainstream consumption. Through an ethnographic account of everyday life at the organic store, the article analyzes how intimacy

The objective of the present work is to, in a single material, combine a number of molecular design strategies that have proven successful in the preparation of high-performance anionexchange membranes (AEMs) for alkaline fuel cells. Hence, we here report on highly conductive and alkali-stable poly(phenylene oxide)s carrying flexible side chains attached via alkyl spacer units, where each side cha

In the Western world, lymphedema most commonly occurs following treatment of cancer. Limb reductions have been reported utilizing various conservative therapies including manual lymph and pressure therapy, as well as by microsurgical reconstruction involving lymphovenous shunts and transplantation of lymph vessels or nodes. Failure of these conservative and surgical treatments to provide complete

Coupling between cytoskeleton and membranes is critical to cell movement as well as organelle formation. Here, we demonstrate that self-assembled single crystals of a dipeptide, diphenylalanine (FF), can interact with liposomes to form cytoskeleton-like structures. Under a physiological condition, disassembly of FF crystals deforms and translocates supported lipid membrane. The system exhibits sim

In this paper, we introduce a new simple but powerful general technique for the study of edge- and vertex-reinforced processes with super-linear reinforcement, based on the use of order statistics for the number of edge, respectively of vertex, traversals. The technique relies on upper bound estimates for the number of edge traversals, proved in a different context by Cotar and Limic [Ann. Appl. P

The aim of the article is, according to the author, to present history of philosophy (and philoso-phy of history) in terms of the British analytical tradition. Rejection of metahistorical purpose accounts for the importance of transdisciplinary analysis in the effort to make sense of historicism; thus, inner “duality” of historiography becomes vital for combining individual and “objective” sides o

Securing the continued growth of the digital economy will largely depend on how we manage consumer data, and which operators and tools we use to moderate, analyze and trade that data, according to guest author Stefan Larsson of Lund University Internet Institute. If users were to begin to perceive the collection and handling of their personal data as illegitimate, he argues, their trust in digital

Complement activation is associated with common rheumatic diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and systemic vasculitis. Evidence linking complement activation to these diseases includes the presence of complement deposition in affected tissues, decreased levels of complement proteins and high levels of complement activation fragments in the blood and/or sy

Metastases are the major cause of cancer-related deaths, but the mechanisms of the metastatic process remain poorly understood. In recent years, the involvement of microRNAs (miRNAs) in cancer has become apparent, and the objective of this study was to identify miRNAs associated with breast cancer progression. Global miRNA expression profiling was performed on 47 tumor samples from 14 patients wit

Recently, next-generation sequencing has been introduced as a promising, new platform for assessing the copy number of transcripts, while the existing microarray technology is considered less reliable for absolute, quantitative expression measurements. Nonetheless, so far, results from the two technologies have only been compared based on biological data, leading to the conclusion that, although t