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Laminin α1 reduces muscular dystrophy in dy2Jmice

Muscular dystrophies, including laminin α2 chain-deficient muscular dystrophy (LAMA2-CMD), are associated with immense personal, social and economic burdens. Thus, effective treatments are urgently needed. LAMA2-CMD is either a severe, early-onset condition with complete laminin α2 chain-deficiency or a milder, late-onset form with partial laminin α2 chain-deficiency. Mouse models dy 3K /dy 3K

New perspectives on the late neolithic of south-western Sweden. an interdisciplinary investigation of the gallery grave falköping stad 5

This article presents the results of an interdisciplinary study combining archaeology, osteology, and stable isotope analyses. The geological conditions and richness of megalithic graves in Falbygden is suitable for studies of Neolithic human remains. Nevertheless, the Late Neolithic period (2350-1700 BC) is poorly investigated. This paper explores new knowledge of the Late Neolithic megalithic po

Care and consequences of traumatic brain injury in Neolithic Sweden : A case study of ante mortem skull trauma and brain injury addressed through the bioarchaeology of care

A number of papers have provided insight into frequencies of violence-related trauma, especially skull trauma, in Northern European skeletal assemblages dating to the Neolithic and Bronze Age. Although the cases are often well described, they lack further discussion about the consequences of skull trauma for the injured individual and the implications for the surrounding society, especially consid

Lifetimes of 2p53p and 3d levels in Ne-like chlorine, Cl VIII

Experimental lifetimes of seven 2p53p and six 2p53d levels in Ne-like chlorine, Cl VIII, have been measured using the beam-foil technique. For the first time in the Ne-sequence, the ANDC method of cascade correction has been applied in the lifetime determination of the 3p levels. This procedure lowered the values by 10 to 30% compared to the results from multiexponential curve-fitting. For all lev

Tidskriften Zenits bokutgivning 1968-1982

Denna artikel beskriver den bokutgivning som skedde inom ramen för tidskriften Zenit mellan åren 1968 och 1982. Zenit gav ut böcker i egen regi men redigerade också tre bokserier på Bo Cavefors förlag(två st.) och på Raben & Sjögren (1). Böckerna gavs typografisk form av Leif Thollander. Tidskriftens Zenits bakgrund i den ""nya vänstern"" skisseras. Bokutgivningens innehåll och karaktär beskri

In situ characterization of the deposition of anatase TiO2 on rutile TiO2(110)

Growing additional TiO2 thin films on TiO2 supstrates in ultrahigh vacuum (UHV)-compatible chambers have many applications for sample preparation, such as smoothing surface morphologies, templating, and covering impurities. However, there has been little study into how to control the morphology of TiO2 films deposited onto TiO2 supstrates, especially using atomic layer deposition (ALD) precursors.

Study of dimuon production in photon-photon collisions and measurement of QED photon structure functions at LEP

Muon pair production in the process e+e- → e+e- μ+μ- is studied using the data taken at LEP1 (√s ≃ mz) with the DELPHI detector during the years 1992-1995. The corresponding integrated luminosity is 138.5 pb-1. The QED predictions have been tested over the whole Q2 range accessible at LEP1 (from several GeV2/c4 to several hundred GeV2/c4) by comparing experimental distributions with distributions

Association between systemic leptin and neurotensin concentration in adult individuals with and without type 2 diabetes mellitus

Purpose: Leptin is an adipokine which regulates appetite and energy balance through a mechanism partially mediated by neurotensin (NT) in central nervous system. Besides acting as a neurotransmitter, NT is expressed in human intestine where it promotes fat absorption and its circulating levels associate with obesity, type 2 diabetes mellitus (T2DM) and cardiovascular disease. Whether a relation ex

Xylo- and arabinoxylooligosaccharides from wheat bran by endoxylanases, utilisation by probiotic bacteria, and structural studies of the enzymes

Xylooligosaccharides (XOS) and arabinoxylooligosaccharides (AXOS) were produced from the insoluble arabinoxylan fraction of pretreated wheat bran by endoxylanases. The glycoside hydrolase (GH) family 10 xylanases GsXyn10A from Geobacillus stearothermophilus and RmXyn10A-CM from Rhodothermus marinus produced the AXOS A3X, A2XX and A2 + 3XX in addition to XOS. RmXyn10A-CM also produced XA2 + 3XX due

Decontextualisation of Street Art

This chapter discusses the increasing tendency to remove street art from its original site for personal gain. It further explores whether/how copyright claims can be an effective means of preventing such extractions.

De novo synthesis of thiamine (vitamin B1) is the ancestral state in Plasmodium parasites – evidence from avian haemosporidians

Parasites often have reduced genomes as their own genes become redundant when utilizing their host as a source of metabolites, thus losing their own de novo production of metabolites. Primate malaria parasites can synthesize vitamin B1 (thiamine) de novo but rodent malaria and other genome-sequenced apicomplexans cannot, as the three essential genes responsible for this pathway are absent in their

Grass biomass as biofuel feedstock –sustainable or not?

Low carbon input due to increasing specialization, intensification and reduced use of bio-fertilizer, leads to soil organic carbon (SOC) decreases in arable land. This is an emerging problem in Europe in general, where 45% of the EU soils have low and declining SOC content. SOC losses from agricultural soils influence soil fertility, putting food security at risk, and contributes to greenhouse gas