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Holocene deglaciation and climate history of the northern Antarctic Peninsula region : a discussion of correlations between the Southern and Northern Hemispheres

The chronology of post-last Glacial Maximum dceglaciation in the northern Antarctic Peninsula region is discussed. It is concluded that, contrary to what was earlier believed, the deglaciation process here was largely out-of-phase with that in the Northern Hemisphere. Although, for global eustatic reasons, the marine-based glaciers may have retreated simultaneously with ice-melting in the Northern

Positioning and Sensing for Vehicular Safety Applications in 5G and beyond

This article presents a shared vision among stakeholders across the value chain on the use of radio positioning and sensing for road safety in the 5G ecosystem. The key enabling technologies and architectural functionalities are explored, focusing on the extremely stringent localization and communication requirements. A case study for joint radar and communication using experimental data showcases

Human Islet MicroRNA-200c Is Elevated in Type 2 Diabetes and Targets the Transcription Factor ETV5 to Reduce Insulin Secretion

MicroRNAs (miRNAs) are part of deregulated insulin secretion in type 2 diabetes (T2D) development. Rodent models have suggested miR-200c to be involved, but the role and potential as therapeutic target of this miRNA in human islets are not clear. Here we report increased expression of miR-200c in islets from T2D as compared with nondiabetic (ND) donors and display results showing reduced glucose-s

Antiphospholipid antibodies in patients with myocardial infarction with and without obstructive coronary arteries

Background: Recent studies demonstrate that prothrombotic antiphospholipid antibodies (aPL) are overrepresented in patients with myocardial infarction (MI) due to coronary artery disease (MICAD). However, it is not known whether aPL differ between the two subsets of MI: MICAD and MI with nonobstructive coronary arteries (MINOCA). Objectives: To determine whether aPL are associated with MINOCA or M

Stretch increases alveolar type 1 cell number in fetal lungs through ROCK-Yap/Taz pathway

Accurate fluid pressure in the fetal lung is critical for its development, especially at the beginning of the saccular stage when alveolar epithelial type 1 (AT1) and type 2 (AT2) cells differentiate from the epithelial progenitors. Despite our growing understanding of the role of physical forces in lung development, the molecular mechanisms that regulate the transduction of mechanical stretch to

Understanding election violence in the Philippines : Beware the unknown assassins of may

Despite election violence being a commonly agreed upon phenomena in the Philippines, there has been a dearth in academic research on the topic in recent years, largely due to a lack of reliable information. To address this, our article adapts recognized methods from studies such as Lindsay Shorr Newman’s 2013 paper, together with Stephen McGrath and Paul Gill’s 2014 research on terrorism and elect

Experimental Evidence for an Attractive p-φ Interaction

This Letter presents the first experimental evidence of the attractive strong interaction between a proton and a φ meson. The result is obtained from two-particle correlations of combined p-φ p¯-φ pairs measured in high-multiplicity pp collisions at s=13 TeV by the ALICE Collaboration. The spin-averaged scattering length and effective range of the p-φ interaction are extracted from the fully corre

Gaming, substance use and distress within a cohort of online gamblers

BACKGROUND: The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) included Internet Gaming Disorder (IGD) as a tentative diagnosis and inquires for additional research. The research on gaming is inconsistent regarding measurement approach and diagnostic cut-offs. Some scholars suggest the core approach, accentuating some of the diagnostic criteria to avoid patholog

Association of mechanical bowel preparation with oral antibiotics and anastomotic leak following left sided colorectal resection : an international, multi-centre, prospective audit

INTRODUCTION: The optimal bowel preparation strategy to minimise the risk of anastomotic leak is yet to be determined. This study aimed to determine whether oral antibiotics combined with mechanical bowel preparation (MBP+Abx) was associated with a reduced risk of anastomotic leak when compared to mechanical bowel preparation alone (MBP) or no bowel preparation (NBP).METHODS: A pre-planned analysi

What is this condition and how could it be treated?

A 67-year-old, previously fit, woman presented with a history of rectal bleeding.Per rectum examination revealed alow rectal mass, which on endoscopy wasdemonstrated to be submucosal. MR rectumconfirmed a 5 cm rectal mass displacing therectum anteriorly. Chest x-ray and abdominalCT did not reveal any metastatic disease. Biopsies were consistent with high grade gastrointestinal stromal cell tumour

The Dynamics of Circulating Heparin-Binding Protein : Implications for Its Use as a Biomarker

Heparin-binding protein (HBP) is a promising biomarker for the development and severity of sepsis. To guide its use, it is important to understand the factors that could lead to false-positive or negative results, such as inappropriate release and inadequate clearance of HBP. HBP is presumably released only by neutrophils, and the organs responsible for its elimination are unknown. In this study,

Crouching TIGER, hidden structure : Exploring the nature of linguistic data using TIGER values

In recent years, techniques such as Bayesian inference of phylogeny have become a standard part of the quantitative linguistic toolkit. While these tools successfully model the tree-like component of a linguistic dataset, real-world datasets generally include a combination of tree-like and nontree-like signals. Alongside developing techniques for modeling nontree-like data, an important requiremen

Patients' experiences before, during, and after a colonoscopy procedure : A qualitative study

Although colonoscopy is a common examination, there is limited research focusing on how patients experience this procedure. It is important that a colonoscopy is tolerated, as it may lead to lifesaving diagnostics and treatment. This study aims to explore adult patients' experience of undergoing a colonoscopy regarding the time prior to, during, and after the procedure. This was a qualitative stud

Multipacting study in INFN-LASA ESS medium-beta cavity

We present Multipacting studies in ESS Medium-Beta cavities of INFN-LASA design with both simulation and experimental results. The simulation on the ideal cavity shape with both FishPact and MultiPac2.1 codes shows that Multipacting appears in a very small region near equator where the weld seam exists. A simulation with more realistic cavity shape considering the weld seam at cell equators has al