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Better implant survival with modern ankle prosthetic designs : 1,226 total ankle prostheses followed for up to 20 years in the Swedish Ankle Registry

Background and purpose — We have previously reported on the prosthetic survival of total ankle replacements (TAR) in Sweden performed between 1993 and 2010. Few other reports have been published on 5- and 10-year survival rates. Furthermore, there is a lack of long-term outcome data on modern prosthetic designs. Therefore, we compared early and current prosthetic designs after a mean 7-year follow

Performance Degradation due to Cut Edge Effect for an Axial-Flux Induction Machine

This paper studies how degraded material properties in near proximity to the cut edge influence the torque performance of an axial-flux induction machine. The magnetically degraded areas are characterized using a layering approach, where the magnetic hysteresis curve describing the material is remodeled so that the field strength required to reach a specific value of magnetic flux density is incre

Effect of medical treatment in patients with systemic right ventricle

Objective: Congenitally corrected and surgical atrial redirected transposition of the great arteries (TGA) represents states where the morphological right ventricle serves as a systemic ventricle (S-RV). The S-RV is prone to failure, but data on medical treatment on this problem is limited. The purpose of this study was to evaluate the survival in adults with S-RV, with or without heart failure tr

Chicken colour discrimination depends on background colour

How well can a bird discriminate between two red berries on a green background? The absolute threshold of colour discrimination is set by photoreceptor noise, but animals do not perform at this threshold; their performance can depend on additional factors. In humans and zebra finches, discrimination thresholds for colour stimuli depend on background colour, and thus the adaptive state of the visua

Large variation in assessment and outcome definitions to describe the burden of long-term morbidity in childhood cancer survivors : A systematic review

We systematically reviewed outcome assessment methods, outcome classification, and severity grading of reported outcomes in studies investigating the burden of physical long-term morbidity in childhood cancer survivors (CCS). A MEDLINE and EMBASE search identified 56 studies reporting on three or more types of health conditions in 5-year CCS, for which information was extracted on outcome types an

Tracing the Full Bimolecular Photocycle of Iron(III)-Carbene Light Harvesters in Electron-Donating Solvents

Photoinduced bimolecular charge transfer processes involving the iron(III) N-heterocyclic carbene (FeNHC) photosensitizer [Fe(phtmeimb)2]+ (phtmeimb = phenyltris(3-methyl-imidazolin-2-ylidene)borate) and triethylamine as well as N,N-dimethylaniline donors have been studied using optical spectroscopy. The full photocycle of charge separation and recombination down to ultrashort time scales was stud

Modeling daily reference evapotranspiration via a novel approach based on support vector regression coupled with whale optimization algorithm

In achieving water resource management goals such as irrigation scheduling, an accurate estimate of reference evapotranspiration (ET0) is critical. Support vector regression (SVR) was applied to the modeling of daily ET0 at three meteorological stations in Iran subject to different climates: Isfahan (arid), Urmia (semi-arid), and Yazd (hyper-arid). Different pre-processing approaches [relief (RL),

Using ecological context to interpret spatiotemporal variation in natural selection

Spatiotemporal variation in natural selection is expected, but difficult to estimate. Pollinator-mediated selection on floral traits provides a good system for understanding and linking variation in selection to differences in ecological context. We studied pollinator-mediated selection in five populations of Dalechampia scandens (Euphorbiaceae) in Costa Rica and Mexico. Using a nonlinear path-ana

SARS-CoV-2 Spike protein binds to bacterial lipopolysaccharide and boosts proinflammatory activity

There is a link between high lipopolysaccharide (LPS) levels in the blood and the metabolic syndrome, and metabolic syndrome predisposes patients to severe COVID-19. Here, we define an interaction between SARS-CoV-2 spike (S) protein and LPS, leading to aggravated inflammation in vitro and in vivo. Native gel electrophoresis demonstrated that SARS-CoV-2 S protein binds to LPS. Microscale thermopho

Magnesium/Nano-hydroxyapatite Composite for Bone Reconstruction : The Effect of Processing Method

Nano-ceramic particles can serve as reinforcing agents for metallic materials to improve their mechanical properties. However, it is important to ensure chemical compatibility between the matrix and particles. In the present study, magnesium composites with and without nano-hydroxyapatite (nHA) particles were fabricated for bone reconstruction applications. Two different techniques were used, Conv

Modelling heat recovery potential from household wastewater

There is a strongly growing interest for wastewater heat recovery (WWHR) in Sweden and elsewhere, but a lack of adequate tools to determine downstream impacts due to the associated temperature drop. The heat recovery potential and associated temperature drop after heat recovery on a building level is modelled for a case study in Linköping, Sweden. The maximum temperature drop reaches 4.2 °C, with

Abdominal Fat and Metabolic Health Markers but Not PNPLA3 Genotype Predicts Liver Fat Accumulation in Response to Excess Intake of Energy and Saturated Fat in Healthy Individuals

Background: Saturated fat (SFA) has consistently been shown to increase liver fat, but the response appears variable at the individual level. Phenotypic and genotypic characteristics have been demonstrated to modify the hypercholesterolemic effect of SFA but it is unclear which characteristics that predict liver fat accumulation in response to a hypercaloric diet high in SFA. Objective: To identif

Fashioning femininity in the 1840s : Charlotte Brontë and Villette

This chapter charts the ways in which Charlotte Brontë uses sartorial details to fashion and re-fashion a possible model of femininity in her last novel, Villette. The protagonist Lucy Snowe, a young woman in her mid-twenties, is situated in between, on the one hand, two teenage girls and, on the other hand, two middle-aged women, who between them represent four different models of fashionable fem

MSIWarp : A General Approach to Mass Alignment in Mass Spectrometry Imaging

Mass spectrometry imaging (MSI) is a technique that provides comprehensive molecular information with high spatial resolution from tissue. Today, there is a strong push toward sharing data sets through public repositories in many research fields where MSI is commonly applied; yet, there is no standardized protocol for analyzing these data sets in a reproducible manner. Shifts in the mass-to-charge