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Searches for New Physics with the ALICE Experiment in pp Collisions

The performance of the ALICE detector in searches for new heavy stable charged particles in pp collisions is discussed in this paper Gluino R-hadron was chosen as an example of a candidate, and cross sections and kinematic properties were obtained from PYTHIA simulations for various gluino masses (100 - 500 GeV/c(2)) Detector response simulations for R-hadrons in the TPC acceptance (vertical bar e

Mixtures of Bose Gases Confined in a Ring Potential

The rotational properties of a mixture of two distinguishable Bose gases that are confined in a ring potential provide novel physical effects that we demonstrate in this study. Persistent currents are shown to be stable for a range of the population imbalance between the two components at low angular momentum. At higher values of the angular momentum, even small admixtures of a second species of a

Vitamin supplementation normalizes total plasma homocysteine concentration but not plasma homocysteine redox status in patients with acute coronary syndromes and hyperhomocysteinemia.

Despite the growing evidence that elevated total homocysteine (tHcy) in plasma is a cardiovascular risk factor, the mechanism underlying the vascular injury is still unknown. Studies are difficult due to the fact that little is known about the formation of different homocysteine species in vivo. In the present study we have investigated the different fractions of tHcy in 21 patients with acute cor

Prophylactic treatment for severe haemophilia: comparison of an intermediate-dose to a high-dose regimen

A multicentre study was performed in Sweden and the Netherlands, comparing effects of two prophylactic regimens in 128 patients with severe haemophilia, born 1970-90. 42 Swedish patients (high-dose prophylaxis), were compared with 86 Dutch patients (intermediate-dose prophylaxis). Patients were evaluated at the date of their last radiological score according to Pettersson. Annual clotting factor c

Mortality among 723 948 foreign- and native-born Swedes 1970-1999

Background: Mortality in a population is regarded as an accurate and valid measure of the population's health. There are a few international studies, predominantly cross- sectional, of mortality among all foreign- born compared with an indigenous population, and the results have varied. No Swedish longitudinal study describing and analysing mortality data was found in a literature review. Methods:

Primal-dual tests for safety and reachability

A methodology for safety verification using barrier certificates has been proposed recently, Conditions that must be satisfied by a barrier certificate can be formulated as a convex program, and the feasibility of the program implies system safety, in the sense that there is no trajectory starting from a given set of initial states that reaches a given unsafe region. The dual of this problem, i.e.

Pressure controlled variable air volume system

There is one primary goal and several secondary goals to fulfill when designing a heating, ventilation and air conditioning (HVAC) system. The main goal is to create an indoor climate that satisfies the user and this should be achieved in the most energy efficient way and with a system that also function in a long-term perspective. Higher supply air flow have the potential of increasing office wor

Status of the physics of substellar objects project

A full understanding of the properties of substellar objects is one of the major challenges facing astrophysics. Since their discovery in 1995, hundreds of brown dwarfs and extrasolar planets have been discovered. While these discoveries have enabled important comparisons with theory, observational progress has been much more rapid than the theoretical understanding of cool atmospheres. The reliab

Long-term effectiveness of sowing high and low diversity seed mixtures to enhance plant community development on ex-arable fields

Questions: How is succession on ex-arable land affected by sowing high and low diversity mixtures of grassland species as compared to natural succession? How long do effects persist? Location: Experimental plots installed in the Czech Republic, The Netherlands, Spain, Sweden and the United Kingdom. Methods: The experiment was established on ex-arable land, with five blocks, each containing three

Regulation of protein kinase B in rat adipocytes by insulin, vanadate, and peroxovanadate. Membrane translocation in response to peroxovanadate

Protein kinase B (PKB) (also referred to as RAC/Akt kinase) has been shown to be controlled by various growth factors, including insulin, using cell lines and transfected cells. However, information is so far scarce regarding its regulation in primary insulin-responsive cells. We have therefore used isolated rat adipocytes to examine the mechanisms, including membrane translocation, whereby insuli

Direct heterogeneous electron transfer reactions of bilirubin oxidase at a spectrographic graphite electrode

Mediatorless (direct) electron transfer between Myrothecium verrucaria bilirubin oxidase and spectroscopic graphite electrode has been demonstrated. The electrochemical activity of the enzyme under aerobic and anaerobic conditions is clearly shown using cyclic voltammetry. It is concluded that the T1 site of the enzyme is the first electron acceptor, both in solution (homogenous case) and when the

UCMA, a novel secreted cartilage-specific protein with implications in osteogenesis

Here we report on the structure, expression and function of a novel cartilage-specific gene coding for a 17 kDa small, highly charged and secreted protein that we termed Ucma (Unique Cartilage Matrix Associated protein). The protein is processed by a furin-like protease into an N-terminal peptide of 37 amino acids and a C-terminal fragment (Ucma-C) of 74 amino acids. Ucma is highly conserved betwe

Low-flow anaesthesia with desflurane: kinetics during clinical procedures

BACKGROUND AND OBJECTIVE: Low-flow anaesthesia is economical and less polluting. The purpose of this study was to determine the inspired and end-tidal desflurane concentrations during anaesthesia with a vaporizer setting maintained at 5%, during low-flow anaesthesia after 120 min with fresh gas inflows of 1.0 and 2.0 L min-1. METHODS: The study was both prospective and randomized, including 56 pat

IL-6 Regulates MMP-10 Expression via JAK2/STAT3 Signaling Pathway in a Human Lung Adenocarcinoma Cell Line

We previously reported that matrix metalloproteinase (MMP)-10 mRNA levels were significantly lower in tumor tissues than in adjacent normal tissues in human non-small cell lung cancer (NSCLC), whereas protein levels of MMP-10 were higher in the tumor tissues than the adjacent tissues. The mechanism of this divergence is still unknown. In the present stud), the role of Janus kinase 2/signal transdu

Role of biochemical markers in the management of osteoporosis

Several serum and urine biochemical markers of bone resorption and formation have been developed. Biochemical bone markers have been used as intermediate end-points in all major studies of anti-osteoporotic therapies. Bone resorption markers, in particular, may add an independent, predictive value to the assessment of bone loss and fracture risk. There are also potential advantages in monitoring a