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Experiences of digital communication with automated patient interviews and asynchronous chat in Swedish primary care : a qualitative study

OBJECTIVES: To explore staff experiences of working with a digital communication platform implemented throughout several primary healthcare centres in Sweden.DESIGN: A descriptive qualitative approach using focus group interviews. Qualitative content analysis was used to code, categorise and thematise data.SETTING: Primary healthcare centres across Sweden, in both rural and urban settings.PARTICIP

Is apparent fixational drift in eye-tracking data due to filters or eyeball rotation?

Eye trackers are sometimes used to study the miniature eye movements such as drift that occur while observers fixate a static location on a screen. Specifically, analysis of such eye-tracking data can be performed by examining the temporal spectrum composition of the recorded gaze position signal, allowing to assess its color. However, not only rotations of the eyeball but also filters in the eye

Radionuclide wiggle matching reveals a nonsynchronous early Holocene climate oscillation in Greenland and western Europe around a grand solar minimum

Several climate oscillations have been reported from the early Holocene superepoch, the best known of which is the Preboreal oscillation (PBO). It is still unclear how the PBO and the number of climate oscillations observed in Greenland ice cores and European terrestrial records are related to one another. This is mainly due to uncertainties in the chronologies of the records. Here, we present new

Repositioning of fluoroquinolones from antibiotic to anti-cancer agents: An underestimated truth

Increasing development costs and higher failure rate in clinical trials has reduced the repertoire of newer drugs in the market for clinical use. The most appropriate approach to end the search for newer drugs is “Repositioning”, as it requires less time and money to explore new indication of existing drug or failed drug. In the past, several drugs have been repositioned for different indication b

Learning curve for robot-assisted laparoscopic radical prostatectomy in a large prospective multicentre study

Objective: Differences in outcome after radical prostatectomy for prostate cancer can partly be explained by intersurgeon differences, where degree of experience is one important aspect. This study aims to define the learning curve of robot-assisted laparoscopic prostatectomy (RALP) regarding oncological and functional outcomes. Materials and methods: Out of 4003 enrolled patients in the LAPPRO tr

KiMoPack : A python Package for Kinetic Modeling of the Chemical Mechanism

Herein, we present KiMoPack, an analysis tool for the kinetic modeling of transient spectroscopic data. KiMoPack enables a state-of-the-art analysis routine including data preprocessing and standard fitting (global analysis), as well as fitting of complex (target) kinetic models, interactive viewing of (fit) results, and multiexperiment analysis via user accessible functions and a graphical user i

Symmetric Mixtures of Pusher and Puller Microswimmers Behave as Noninteracting Suspensions

Suspensions of rear- and front-actuated microswimmers immersed in a fluid, known respectively as "pushers"and "pullers,"display qualitatively different collective behaviors: beyond a characteristic density, pusher suspensions exhibit a hydrodynamic instability leading to collective motion known as active turbulence, a phenomenon which is absent for pullers. In this Letter, we describe the collecti

Demo : Millimeter-Wave Massive MIMO Testbed with Hybrid Beamforming

Massive multiple-input multiple-out (MIMO) is vital in millimeter-wave (mmWave) bands to obtain large array gains. However, there are practical challenges, such as high hardware cost and power consumption in such systems. A promising solution to these problems is to adopt a hybrid beamforming architecture. This architecture has a much lower number of transceiver (TRx) chains than the total antenna

An Existence Theory for Small-Amplitude Doubly Periodic Water Waves with Vorticity

We prove the existence of three-dimensional steady gravity-capillary waves with vorticity on water of finite depth. The waves are periodic with respect to a given two-dimensional lattice and the relative velocity field is a Beltrami field, meaning that the vorticity is collinear to the velocity. The existence theory is based on multi-parameter bifurcation theory.

The role of hand-held ultrasound for cardiopulmonary assessment during a pandemic

During the COVID-19 pandemic, we are likely to see a significant increase in the requests for rapid assessment of cardiac function, due to the frequent pre-existence of cardiac pathologies in patients admitted to hospital, and to the emergence of specific cardiac manifestations of this infection, such as myocarditis, sepsis related cardiomyopathy, stress induced cardiomyopathy and acute coronary s

A Proposal for the Performance, Classification, and Reporting of Lymph Node Fine-Needle Aspiration Cytopathology : The Sydney System

BACKGROUND: The evaluation of lymph nodes (LN) by fine-needle aspiration cytology (FNAC) is routinely used in many institutions but it is not uniformly accepted mainly because of the lack of guidelines and a cytopathological diagnostic classification. A committee of cytopathologists has developed a system of performance, classification, and reporting for LN-FNAC. METHODS: The committee members pre

Nullstellensatz size-degree trade-offs from reversible pebbling

We establish an exactly tight relation between reversible pebblings of graphs and Nullstellensatz refutations of pebbling formulas, showing that a graph G can be reversibly pebbled in time t and space s if and only if there is a Nullstellensatz refutation of the pebbling formula over G in size t + 1 and degree s (independently of the field in which the Nullstellensatz refutation is made). We use t

Novel Insights into Haematopoietic Stem Cell Regulation and Function

The haematopoietic stem cell (HSC) is a somatic stem cell essential for life long haematopoiesis; HSCs have the capability to differentiate into all mature types of blood cells and can also undergo self-renewal to maintain their own numbers. They also have the potential to reconstitute a complete haematopoietic system following HSC transplantation, also known as bone marrow transplantation, which

Mechanics of accelerated strain hardening in harmonic-structure materials

Harmonic-structure (HS) design is one of the most efficient in the family of architected gradient-structure materials recently attracting increasing attention in global material science community due to leading structural performance characteristics. This work studies in situ the mechanics of plastic deformation in HS materials on the example of commercially pure nickel (Ni) during uniaxial tensil

Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17

BACKGROUND: Oral rehydration solution (ORS) is a form of oral rehydration therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according to UNICEF estimates, less than half of children younger than 5 years with diarrhoea in low-income and middle-income countries (LMICs) received ORS in 2016. A variety of recommended home fluids (RHF) exist as alternative f

Representation of intimate partner violence against women in Swedish news media: a discourse analysis.

Despite being rated as some of the world’s most gender equal countries, Sweden and neighboring Nordic nations show high rates of intimate partner violence against women (IPVAW). As the news media contribute to the shaping of public attitudes, this article pursues a two-step discourse analysis of how IPVAW was represented in seven Swedish newspapers during 2018. Although an individualistic discours

Independent Validation of Early-Stage Non-Small Cell Lung Cancer Prognostic Scores Incorporating Epigenetic and Transcriptional Biomarkers With Gene-Gene Interactions and Main Effects

Background: DNA methylation and gene expression are promising biomarkers of various cancers, including non-small cell lung cancer (NSCLC). Besides the main effects of biomarkers, the progression of complex diseases is also influenced by gene-gene (G×G) interactions. Research Question: Would screening the functional capacity of biomarkers on the basis of main effects or interactions, using multiomi

Displaced femoral neck fractures in patients 60-69 years old – mortality and patient reported outcomes in a register cohort

Registerstudie på data från Svenska Frakturregistret, SFR. Vi hittade 723 patienter i åldern 60-69 år som hade en dislocerad höftfraktur. Standardbehandling i Sverige är total höftplastik, men en del patienter behandlas även med skruvar/spikar. Patienter med skruvar/spikar måste opereras om i 1/3 av fallen pga haveri i frakturen och erhåller då total höftplastik. Trots detta uppvisade denna grupp BackgroundSeveral randomized studies have compared arthroplasty and internal fixation (IF) and found better patient reported outcome measure (PROM) and fewer reoperations for arthroplasty. But consensus is lacking regarding which method to use in the "young elderly” patients aged 60-69; IF tend to fail in up to 1/3 of the cases but can offer the benefits of a biologically intact hip if successful.