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Specific effects of platelet derived growth factor (PDGF) on fetal rat and human dopaminergic neurons in vitro

The neurotrophic effects of the BB isoform of platelet-derived growth factor (PDGF) on rat and human fetal mesencephalic dopaminergic neurons have been characterized in vitro. A dose-response analysis demonstrated maximal responses at 30 ng/ml of PDGF-BB. This concentration resulted in a marked increase in the survival and neurite outgrowth from rat and human tyrosine hydroxylase-(TH) positive, pr

Coherent two-dimensional spectroscopy of a Fano model

The Fano line shape arises from the interference of two excitation pathways to reach a continuum. Its generality has resulted in a tremendous success in explaining the line shapes of many one-dimensional spectroscopies - absorption, emission, scattering, conductance, photofragmentation - applied to very varied systems - atoms, molecules, semiconductors, and metals. Unraveling a spectroscopy into a

Academic Entrepreneurship and Exchange of Scientific Resources : Material Transfer in Life and Materials Sciences in Japanese Universities

This study uses a sample of Japanese university scientists in life and materials sciences to examine how academic entrepreneurship has affected the norms and behaviors of academic scientists regarding sharing scientific resources. Results indicate that high levels of academic entrepreneurship in a scientific field are associated with less reliance on the gift-giving form of sharing (i.e., generali

Metal-passivated PbS nanoparticles : Fabrication and characterization

Organic-shell-free PbS nanoparticles have been produced in the size range relevant for quantum-dot solar cells (QDSCs) by a vapor aggregation method involving magnetron reactive sputtering. This method creates a beam of free 5-10 nm particles in a vacuum. The dimensions of the particles were estimated after their deposition on a substrate by imaging them using ex situ SEM and HRTEM electron micros

Use of dissertation data in science policy research

Although the contribution of scientometric literature to policies on academic science has been substantial, the literature has focused primarily on the production of scientific knowledge, whereas limited attention has been paid to the other critical mission of academic institutions, i.e., education or the production of scientists. To address this limitation and better inform policymakers, the curr

ESS progressing into construction

The construction of the European Spallation Source, ESS, started in summer 2014. At the site in Lund, the accelerator tunnel will be completed at the time of IPAC16, while prototyping and manufacturing or preparations for manpower contributions are going on in more 23 laboratories distributed over the 12 European countries collaborating on the accelerator project. Major technical milestones have b

Detection of subclinical vitamin K deficiency in neurosurgery with PIVKA-II

Vitamin K is known for supporting the carboxylation of hepatic coagulation proteins. Levels of proteins induced by vitamin K absence for factor II (PIVKA-II) reflect hypocarboxylated prothrombin and can be used to detect subclinical vitamin K deficiency. The aim of this study was to determine the prevalence of perioperative subclinical vitamin K deficiency among neurosurgical patients using PIVKA-

Impact of inbreeding on scientific productivity : A case study of a Japanese university department

Recent science policies emphasize academic mobility and denounce inbreeding as an impediment to scientific productivity. This study aims to investigate the impact of inbreeding on productivity, distinguishing various forms of inbreeding, and to explore the mechanism behind which inbreeding is translated into productivity, drawing on in-depth longitudinal data of academics' careers in a university

In vivo dopamine agonist properties of rotigotine : Role of D1 and D2 receptors

Rotigotine acts in vitro as a full agonist of dopamine D1 receptors at concentrations almost superimposable to those at which it acts on D2 receptors. However in vivo evidence of the differences between the agonist activity of rotigotine at D1 receptors from that on the D2 receptors has not been provided yet. In order to test the ability of rotigotine to stimulate dopamine D1 and D2 receptors in v

Determination of the neutron-capture rate of C 17 for r -process nucleosynthesis

With the RB3-LAND setup at GSI we have measured exclusive relative-energy spectra of the Coulomb dissociation of C18 at a projectile energy around 425A MeV on a lead target, which are needed to determine the radiative neutron-capture cross sections of C17 into the ground state of C18. Those data have been used to constrain theoretical calculations for transitions populating excited states in C18.

Commissioning of the harmonic cavities in the MAX IV 3 GeV ring

The MAX IV 3 GeV storage ring operates with beam of high current and ultralow emittance. These beam parameters in combination with the small effective aperture enhance possible collective beam instabilities. Three passive harmonic cavities are installed to introduce bunch lengthening and tune spread, leading to decoupling of the bunch spectrum from the machine effective impedance and mitigating in

SLAC FACET-II positron damping ring magnet design

The FACET-II facility, currently being designed at SLAC, will contain a small 20 m circumference, 335 MeV, positron damping ring. The ring has to fit in the existing linac tunnel, meaning that a compact lattice with short distances between magnets is required. The detailed magnet design is done in Opera-3d, with a finite element model of a full damping ring arc being simulated. This article presen