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Popular Abstract in Swedish Polyomavirus är en familj av små DNA-virus som har onkogena egenskaper i försöksdjur i celler in vitro. De humana polyomavirusen BK virus (BKV) och JC virus (JCV) infekterar en stor del av befolkningen. Ungefär 70-80 % av vuxna är seropositiva, har antikroppar mot BKV och JCV. Primär infektion inträffar oftast under barndomen och är ofta subklinisk. Efter primära infektThe human polyomaviruses BKV and JCV are endemic and infect > 70% of population worldwide. Primary infections occur during childhood and are largely subclinical. Following primary infection, both viruses persist as latent infections in the kidneys and B lymphocytes. Under conditions of severe immunosuppression like leukaemia, organ transplantation and AIDS, the viruses can reactivate and cause dis

OBJECTIVE: To investigate possible associations between use of cardiovascular drugs and suicide. DESIGN: Cross sectional ecological study based on rates of use of eight cardiovascular drug groups by outpatients. A population based cohort study including users of drugs to control hypertension. SUBJECTS: The ecological study included 152 of Sweden's 284 municipalities. The cohort study included all

For many years, newborn infants admitted to neonatal intensive care units have had routine electrocardiography and been monitored for respiratory rate, heart rate, oxygen saturation, and blood pressure. Only recently has it also been considered important to monitor brain function using continuous electroencephalography. The role of cerebral function monitoring in sick full term and preterm infants

A girl with polydactyly has had respiratory tract problems, including atelectasis, since birth. She has a high arched palate, a tongue hamartoma and dysmorphic face. Electron microscopy of nasal and bronchial brush biopsies repeatedly revealed centriole/basal body disarray and extreme sparseness of cilia. At the age of 2 years and 11 months, she displayed retardation of both motor and mental skill

The three dimensional structures of human prostate specific antigen (PSA) and glandular kallikrein (hGK) were modeled based on porcine pancreatic kallikrein A. High sequence similarity and conserved framework of serine proteases enabled accurate modeling. The catalytic site region consisting of catalytic triad, residues forming oxyanion hole and main-chain substrate binding residues were conserved

Aims and objectives. The aim of the study was to investigate the quality of life and related factors among older people who are in pain and in need of help to manage daily living. Background. To intervene against the low quality of life in nursing care knowledge about factors affecting it is needed and this is especially important for vulnerable people such as those who suffer from pain and who a

The objective of this study was to investigate B-lymphocyte reconstitution in patients undergoing allogeneic haematopoietic stem cell transplantation (HSCT) after myeloablative conditioning (MAC) or reduced-intensity conditioning (RIC) regimens. B-lymphocyte reconstitution was studied by monitoring the CDR3 repertoire with spectratyping. We demonstrate a delay in the recovery of the B-lymphocyte r

The paper presents numerical results concerning the so-called laminating effect of laminatedbeams. Using the finite-element method, it is shown that the assumption often made of a stress redistribution taking place around weak zones is not necessarily true. A fracture mechanics approach to a possible explanation for the laminating effect is also presented. Here a nonlinear fracture mechanics model

Popular Abstract in Swedish Två observationer tjänar som utgångspunkt för denna avhandling: (1) globaliseringens allt snabbare och mer eller mindre gränslösa flöde av information har medfört ökad press på företag och organisationer, liksom stater och regioner, att ständigt förnya sig för att kunna behålla sin konkurrenskraft. (2) kunskapsintensiv industri tenderar att samlas i geografisk närhet tiThe accelerated speed and intensity of global interconnections in all segments of society during the last couple of decades have had a profound impact on the workings of contemporary capitalism. Increased pressure is put on national and regional economies to continuously upgrade their competitive advantages, at the same time as new learning opportunities occur at a faster rate than ever. For reaso

This report presents a survey of current simulation tools in the area of integrated control and real-time systems design. Each tool is presented with a quick overview followed by a more detailed section describing comparative aspects of the tool. These aspects describe the context and purpose of the tool (scenarios, development stages, activities, and qualities/constraints being addressed) and the