This thesis describes the development of a one-step, specific, cost-effective and rapid in vitro point-of-care immunoassay test based on a unique magnetic immunoassay principle. The principle in question is based on a non-competitive heterogeneous immunoassay in a one-step analysis, relying on magnetic permeability detection. The heterogeneous immunoassay is performed in disposable reagent vials,

År 1900 blev botanisten Carl Lindman ansvarig för återutgivningen av en hundra år gammal illustrerad flora, J. W. Palmstruchs Svensk botanik (1802–43). De gamla handkolorerade kopparsticken undersöktes noggrant, korrigerades och försågs med nya förstorade detaljer och trycktes sedan med färglitografi. I denna artikel studeras, ur ett bokhistoriskt perspektiv, hur den nya formen påverkar innehålletIn 1900 the Swedish botanist Carl Lindman was assigned responsibility for the republication of a one-hundred-year old illustrated flora, J. W. Palmstruch’s Svensk botanik (1802–43). The old hand-colored copperplates were meticulously examined, corrected, and supplied with new magnified details and then printed in color lithographs. This article closely examines, from a book historical perspective,

The photothermoelectric (PTE) effect uses nonuniform absorption of light to produce a voltage via the Seebeck effect and is of interest for optical sensing and solar-to-electric energy conversion. However, the utility of PTE devices reported to date has been limited by the need to use a tightly focused laser spot to achieve the required, nonuniform illumination and by their dependence upon the See

BACKGROUND: Several studies have described hypercoagulability in neurosurgery with craniotomy for brain tumor resection. In this study, hydroxyethyl starch (HES) 130/0.42 was used for hemodynamic stabilization and initial blood loss replacement. HES can induce coagulopathy with thromboelastographic signs of decreased clot strength. The aim of this study was to prospectively describe perioperative

Modern software development relies on code reuse, which software engineers typically realise through handwritten abstractions, such as functions, methods, or classes. However, such abstractions can be challenging to develop and maintain. One alternative form of re-use is copy-paste-modify, a methodology in which developers explicitly duplicate source code to adapt the duplicate for a new purpose.

We examine the impact of competition on a firm's incentive to relax the standards of its inspection to its customers in the Swedish motor vehicle inspection market, which is heavily regulated and consciously designed to mitigate incentives to deviate from the regulation. We use a panel dataset representing 22.5 million car roadworthiness tests during the period 2010--2015. Fixed effects and instru

The three factors, p53, the microRNA-34 family and Sirtuin 1 (SIRT1), interact in a positive feedback loop involved in cell cycle progression, cellular senescence and apoptosis. Each factor in this triad has roles in metabolic regulation, maintenance of mitochondrial function, and regulation of brain-derived neurotrophic factor (BDNF). Thus, this regulatory network holds potential importance for t

The thermal environment experienced by birds during early postembryonic development may be an important factor shaping growth and survival. However, few studies have directly manipulated nest temperature (T n) during the nestling phase, and none have measured the consequences of experimental heat stress on nestlings’ body temperature (T b). It is therefore not known to what extent any fitness consThe thermal environment experienced by birds during early postembryonic development may be an important factor shaping growth and survival. However, few studies have directly manipulated nest temperature (T n) during the nestling phase, and none have measured the consequences of experimental heat stress on nestlings’ body temperature (T b). It is therefore not known to what extent any fitness cons

Objective To describe treatment patterns in the Swedish early psoriatic arthritis cohort (SwePsA) of the mono-/oligo-arthritic (M/O) and polyarthritis (P) and identify early predictive factors for treatment with disease-modifying anti-rheumatic (DMARD), non-steroidal anti-inflammatory drugs (NSAID), and tumour necrosis factor inhibition (TNFi) after 5 years. Methods Data for 198 M/O and P PsA were

In most industrial product development projects, computer-based design analysis, or simply design analysis, is frequently utilized. Several design analysis process models exist in the literature for the planning, execution and follow-up of such design analysis tasks. Most of these process models deal explicitly with design analysis tasks within two specific contexts: the context of design evaluati

We describe the main features and preliminary evaluation of Positive Technology, a free mobile platform for the self-management of psychological stress (http://positiveapp.info/). The mobile platform features three main components: (i) guided relaxation, which provides the user with the opportunity of browsing a gallery of relaxation music and video-narrative resources for reducing stress; (ii) 3D

The prospects of domestic punishment might compel leaders responsible for the initiation of the war to continue fighting until they achieve favorable war outcomes (Croco 2011, 2015). As applied to war duration, this logic implies that ‘culpable’ leaders do not have incentives to end a war that will bring defeat. This paper argues that leaders can escape this dilemma by blaming and replacing their

Paragone is a well-known and often applied category to discuss the interrelationship of the Sister Arts. However, it does not seem to be a sufficient label to respond to the general questions raised about representation, mimesis and identity brought together in the postmodern intermedial writing of The Matisse Stories (1993), by A.S. Byatt, which was influenced by French avant-garde literature and

Objective: To compare the rate of lymphatic complications in women with endometrial cancer undergoing sentinel lymph node biopsy versus a full pelvic and infrarenal paraaortic lymphadenectomy, and to examine the overall feasibility and safety of the former. Methods: A prospective study of 188 patients with endometrial cancer planned for robotic surgery. Indocyanine green was used to identify the s

Aim: The aim of this pilot study was to explore the Fear of Birth Scale in a mixed sample of women of childbearing age, by investigating the levels of childbirth fear and the content of women's thoughts when completing the scale. Methods: A cross-sectional mixed method study of 179 women who completed a short questionnaire and a think aloud interview. Results: The mean score of the Fear of Birth S

Objective: Elevated luteinizing hormone (LH) with normal testosterone (T) suggests compensated dysregulation of the gonadal axis. We describe the natural history, risk factors and clinical parameters associated with the development of high LH (HLH, LH >9.4 U/L) in ageing men with normal T (T ≥ 10.5 nmol/L). Design, Patients and Measurements: We conducted a 4.3-year prospective observational study

Objective: Retinopathy of prematurity (ROP) is a multifactorial disease linked to low insulin-like growth factor (IGF)-I levels and perhaps to postnatal inflammation. Here, we investigated the longitudinal postnatal serum concentrations of pro-inflammatory cytokines interleukin (IL)-6 and tumor necrosis factor (TNF)-α in relation to IGF-I levels and ROP. Design: The study cohort included 52 infant