BackgroundImproved quality of life (QoL) is one of the most important objectives in the treatment of epilepsy. Recent prospective, clinical studies proved no significant differences between brand antiepileptic drugs (AEDs) and their generic equivalents in terms of seizure control, pharmacokinetics, or safety. In this study, we focused on possible changes in QoL and adverse events in connection wit

Background and aim: As an increasing number of people are living and ageing with the consequences ofstroke, the rehabilitation and support provided for this group needs to have a long-term perspective. Moreover,to prevent long-term activity limitations and participation restrictions after stroke, increased knowledge is neededregarding how engagement in different types of activities develops beyond

Extracting the latent knowledge from Twitter by applying spatial clustering on geotagged tweets provides the ability to discover events and their locations. DBSCAN (density-based spatial clustering of applications with noise), which has been widely used to retrieve events from geotagged tweets, cannot efficiently detect clusters when there is significant spatial heterogeneity in the dataset, as it

Since the 1970s, the degrowth idea has been proposed by scholars, public intellectuals and activists as a powerful call to reject the obsession of neoliberal capitalism with economic growth, an obsession which continues apace despite the global ecological crisis and rising inequalities. In the past decade, degrowth has gained momentum and become an umbrella term for various social movements which

Pulmonary hypertension is a common consequence of left heart disease, associated with poor prognosis. The pulmonary hypertension in left heart disease is initially caused by a passive congestion of the pulmonary circuit but may, if longstanding, result in endothelial dysfunction and excessive vasoconstriction. In some cases pulmonary vascular remodeling occur, further complicating the condition an

For a firm in an open source software (OSS) ecosystem, the requirements engineering (RE) process is rather multifaceted. Apart from its typical RE process, there is a competing process, external to the firm and inherent to the firm’s ecosystem. When trying to impose an agenda in competition with other firms, and aiming to align internal product planning with the ecosystem’s RE process, firms need

Förutom att Malmö har flest anmälda brott i relation till sin folkmängd, är det också en av de städer i landet med högst andel skjutvapenrelaterat våld. Våra tidigare studier visar att de som begår grova brott som mord eller dråp och försök till mord eller dråp i Malmö främst är ensamstående, har ingen psykiatrisk diagnos och använder sig främst av kniv eller annat vasst tillhygge vid sina dåd, ävIn addition to Malmö having the most reported crimes in relation to its population, it is also one of the cities in the country with the highest percentage of gun-related violence. Our earlier studies show that people who commit serious crimes such as homicide or attempted homicide in Malmö are primarily single, have no psychiatric diagnosis and mainly use knives or other sharp weapons to commit t

The gravitational interaction between two objects on similar orbits can effect noticeable changes in the orbital evolution even if the ratio of their masses to that of the central body is vanishingly small. Christou (Icarus 174:215–229, 2005) observed an occasional resonant lock in the differential node ΔΩ between two members in the Himalia irregular satellite group of Jupiter in the N-body simula

In the hadroproduction of charm in the context of string fragmentation, the pull of a beam remnant at the other end of a string may give a charm hadron more energy than the perturbatively produced charm quark. The collapse of a low-mass string to a single hadron is the extreme case in this direction, and gives rise to asymmetries between charm and anticharm hadron spectra. We study these phenomena

Botulinum neurotoxin B is a Food and Drug Administration-approved therapeutic toxin. However, it has lower binding affinity toward the human version of its major receptor, synaptotagmin II (h-Syt II), compared to mouse Syt II, because of a residue difference. Increasing the binding affinity to h-Syt II may improve botulinum neurotoxin B's therapeutic efficacy and reduce adverse effects. Here we ut

Arbetet omfattar uppföljningav ställda kriterier förlåg klimatpåverkan från betong vid upphandling av betongstommeför brf. Viva i Göteborg. Kriterierna följdes upp dels genom att LCA studien som genomförtsunder programskedet uppdaterades med data för den färdigupphandlade byggnadenoch dels genom att interljuva ett urval av aktörer för att få en inblick över hur branschen ser på de ställda kraven. This work includes monitoring of set criteria for low climate impact from concrete in procurement of concrete structures for brf. Viva in Gothenburg. The criteria were followed up by updating the LCA study performed during the program phase with new data for the completed building, plus a selection of the project stakeholders were also interviewed to gain an insight into how the industry received

The introduction of standardized APIs for ray tracing, together with hardware acceleration, opens up possibilities for physically based lighting in real-time rendering. Light importance sampling is one of the fundamental operations in light transport simulations, applicable to both direct and indirect illumination. This chapter describes a bounding volume hierarchy data structure and associated sa

Lung cancer is a common cancer type associated with poor prognosis. Even in the group of patients with earlystage tumors, for which curative treatment is possible, lung cancer recurrence is frequent. The aim of this thesis was to investigate the potential prognostic role of mutations in tumor specimens, blood-based proteins and circulating tumor DNA.In study I, we performed EGFR mutation detection