Popular Abstract in Swedish 6 Populärvetenskaplig sammanfattning 6.1 Proteiner produceras av våra gener Nyligen bestämdes sekvensen för det mänskliga genomet bestående av 30 000 gener. Varje gen kodar för minst ett protein. All information finns i generna men för att förstå vad generna gör behöver vi studera proteinerna de kodar för. I denna avhandling presenteras några proteinstrukturer. Man kaThe Mg2+ and Mn2+ structures of calbindin D9k have been determined and they reveal a conformational change compared to the structures of apo and (Ca2+)2-calbindin D9k. These findings are unique, since normally calcium and not magnesium is known to induce conformational changes of EF-hand proteins. It has also been shown that calbindin D9k binds one Mg2+ (Kd=1mM) in the regular C-terminal EF-hand c

Livsstil och förhållanden för familjer inom det högre borgerskapet i Lund ca 1800-1850. Familjerna Faxe, Tegnér, Tegman, Lovén, Bring, Thomander, Borg och Gleerup nämns, och kvinnornas förhållanden nämns speciellt.

If engineering designers consciously design product and package in an integrated manner, there is a great potential for industrial global enterprises to develop and produce mechanical products, such as exhaust extraction systems, ear washer machines and fuel handling systems while simultaneously obtaining error-free deliveries, saving costs and avoiding quality problems. Thus, the authors of this

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This paper investigates both positional dependence in systems with friction and the influence an increase in temperature has on the friction behavior. The positional dependence is modeled with a Radial Basis Function network and the temperature dependence is modeled as a first order system with the power loss due to friction as input, eliminating the need for temperature sensing. The proposed meth

This work concerns an experimental study of pressure drop and heat transfer for turbulent flow inside a U-duct with relevance for tip cooling of gas turbine blades. The U-duct models the internal blade cooling flow passages. Both friction factors and convective heat transfer coefficients were measured along the bend (turn) part of the U-duct for three different rib configuration cases, namely (a)

Popular Abstract in Swedish Vi lever i ett samhälle under ständig utveckling där användandet av nya kemikalier ökar explosionsartat. Med vardagligt användande av avancerade material såsom extremt tunna skärmar, billiga och miljövänliga bekämpningsmedel och läkemedel – vilka ofta är inspirerade av naturens komplexitet – kommer ett behov av organisk syntes. För att tillverka den här typen av komplicThis thesis deals with the development of novel methodologies for the synthesis of hetero- and carbocycles enabled by transition metal catalysis. The second chapter of the thesis describes a gold-catalyzed three-component reaction to form a variety of substituted oxazoles from readily available N-benzylimines, terminal alkynes, and acyl chlorides. Sacrificial benzyl groups are used to merge two o