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BackgroundPatients with Huntington's disease display symptoms from both the central nervous system and peripheral tissues. Mitochondrial dysfunction has been implicated as part of the pathogenesis of the disease and has been reported in brain tissue and extracerebral tissues, such as muscle and blood cells, but the results are inconsistent. Therefore, the authors performed a refined evaluation of

In this paper we report some results of our numerical simulations of sprays in compressible flows using Large Eddy Simulation. The combined LES- and spray code has been applied to the computation of the flow and spray injection into a swirl generator of a gas-turbine. The interaction between the spray jet and the flow field has been investigated. A dynamic SGS model has been used and results have

Versioning of components in a system is a well-researched field where various adequate techniques have already been established. In this paper, we look at how versioning can be extended to cover also the structural aspects of a system. There exist two basic techniques for versioning - intentional and extensional - and we propose a unified extensional versioning model for versioning of both compone

A high order Cartesian grid method is developed and applied to large eddy simulations (LES) of isothermal and reactive turbulent flows. Cartesian grid methods are potentially the most suitable numerical methods for LES because of its economical storage requirement, less computational effort per computational cell, fast numerical convergence and feasibility for constructing higher order finite diff

This paper presents a technique for product configuration modelling based on object-orientation and attribute grammars. The technique allows efficient interactive configurator tools to be generated for specified product families. Additional benefits include a high degree of checkability, early validation, readability, and reusability. The technique is particularly aimed at mass-customization produ

Inom fysik försöker vi beskriva naturfenomen med matematiska modeller. Beroende på vilket system som ska beskrivas är olika modeller relevanta. På väldigt långa avstånd är gravitation den viktigaste kraften. Till exempel så beskrivs solsystemets dynamik av gravitation. På de kortaste avstånd som människan lyckats studera är det istället den elektromagnetiska, den svaga och den starka kraften som äIn this thesis we use effective field thory methods and models for low energy QCD in two different contexts. One is direct calculation of contributions to the anomalous magnetic moment of the muon, muon g-2. The other is estimates of systematic sources of uncertainty in lattice QCD simulations. The work is presented in five papers. Papers II, IV and V describe calculations for muon g-2 and papers

I många forskares värld utgör seminarierummet en förtätad plats. Själva idén om det akademiska textseminariet är omhuldad, särskilt inom de humanistiska och samhällsvetenskapliga ämnesområdena. Seminariet är en väl förankrad arbetsform inom universitetet. Det är där de höga tankarna tänks och ventileras, det är där lärande och forskning går hand i hand, och det är där kollegialiteten praktiseras i

What are the underlying motivations for the conceptualization of events? Recent studies show that when people are asked to use nonverbal gestures to describe transitive events they prefer the semantic order Agent-Patient-Act, analogous to SOV in grammatical terms. The original explanation has been that this pattern reflects a cognitively “natural order” for the conceptualization of events. However