Context: SHBG regulates free sex steroid levels, which in turn regulate skeletal homeostasis. Twin studies have demonstrated that genetic factors largely account for interindividual variation in SHBG levels. Glucuronidated androgen metabolites have been proposed as markers of androgenic activity. Objective: Our objective was to investigate whether polymorphisms in the SHBG gene promoter [(TAAAA)(n

Background: Symptoms from the upper gastrointestinal tract are frequently encountered in clinical practice and may be of either organic or functional origin. For some of these conditions, according to the literature, certain management strategies can be recommended. For other conditions, the evidence is more ambiguous. The hypothesis that guided our study design was twofold: Management strategies

Popular Abstract in Swedish Avhandlingen syftar till att undersöka arbetslöshetens sociala konsekvenser och försöka ge en rimlig tolkning av variationer i arbetslöshetserfarenheter med hjälp av en teoretisk modell - ekonomi-skam modellen. Fokus ligger på att söka lyfta fram och visa på betydelsen av ekonomiska påfrestningar i kombination med skamupplevelser som en faktor för att förstå skillnader The purpose of this study has been to investigate the social consequences of unemployment and to give a possible interpretation of unemployment experiences through the application of the economy-shame model. It intends to put forward and show the significance of economic stress in combination with the feeling of shame as a factor important for the understanding of differences in unemploy-ment expe

This study examined the neurophysiological effects of cannabis. Cerebral blood flow (CBF) was measured in 12 long-term cannabis users shortly after cessation of cannabis use (mean 1.6 days). The findings showed significantly lower mean hemispheric blood flow values and significantly lower frontal values in the cannabis subjects compared to normal controls. The results suggest that the functional l

The aim of this study was to evaluate the synthetic C6 peptide test as a first-line test in a two-tiered scheme for Borrelia serology in a clinically well-characterized population of patients with Lyme borreliosis in Kalmar County, Sweden. The study population consisted of a prospective group (n=200), a control group (n=255), and a retrospective group (n=29). The test panel consisted of the Immune

With the attempts to achieve higher thermal efficiency, turbine blades are exposed to very high temperature gases and may undergo severe thermal stress and fatigue. Thus, in order to develop optimal cooling strategies and reduce the heat transfer it is important to obtain a good understanding of both the complex flow field and the heat transfer characteristics in turbine rotor/stator hot-gas passa

I denna rapport redovisas dels en övergripande bild över arbetstidsförkortningsdebatten och dels tre försöksprojekt med arbetstidsförkortning som bedrevs under ett och ett halvt år i Malmö kommun. Det hävdas att debatten har utvecklats till en kontrovers i vilken olika grupperingar av debattaktörer kan urskiljas utifrån sina ställningstaganden till reformen, och att det kunskapsunderlag som finns

The photodissociation of bromobenzene in solution was investigated with ultrafast transient absorption spectroscopy following excitation at 266 nm. Ab initio calculations of lower singlet and triplet states were performed in order to guide the interpretations. The main feature of the kinetics measured between 300 and 930 nm in acetonitrile is a 9±1 ps decay, which we mainly assign to predissociati

In order to demonstrate the feasibility of the proton microprobe in the analysis of dermatological material when a spatial resolution of a few micrometres is sufficient and to compare it with the electron microprobe technique, duplicate sections of human skin have been analysed with both methods. A skin sample was obtained from each of three healthy volunteers. After cryosectioning (12 μm) and fre

New radiative lifetimes for 20 levels of Pr II have been measured using the time-resolved laser-induced fluorescence (LIF) technique. The combination of these experimental values with theoretical branching fractions (BF) obtained with the pseudo-relativistic Hartree-Fock (HFR) approach has allowed us to determine oscillator strengths and transition probabilities for about 150 lines appearing in th

Popular Abstract in Swedish Idag använder många offentliga beslutsfattare en stor andel av sin tid åt att söka introducera nya policies, program och tekniker. Medborgerligt missnöje med offentlig service och offentliga sparbeting gör att många beslutsfattare verkar i en turbulent omvärld, där förändringstrycket är stort. Impulser till policyförändring kan komma från många olika håll. I min studie This thesis discusses an alternative to the conventional policy diffusion approach, i.e. the social constructivist translation perspective. Within the translation perspective, policy diffusion is defined as a process where meaning is constructed by temporally and spatially disembedding policy ideas from their previous context and using them as models for policy change in a new context. This brings

Assembly of MHC class I molecules in the ER is regulated by the so-called loading complex (LC). This multiprotein complex is of definite importance for class I maturation, but its exact organization and order of assembly are not known. Evidence implies that the quality of peptides loaded onto class I molecules is controlled at multiple stages during MHC class I assembly. We recently found that tap