Sökresultat
Filtrera
Filtyp
Din sökning på "*" gav 531329 sökträffar
Subcellular distribution and autophosphorylation of calcium/calmodulin- dependent protein kinase II-α in rat hippocampus in a model of ischemic tolerance
A brief period of sublethal ischemia induces resistance to a subsequent, otherwise lethal, ischemic insult, a process named ischemic tolerance or preconditioning. A persistently disturbed cell signaling during reperfusion after cerebral ischemia has been proposed to contribute to ischemic cell death. Here, we report on the effect of ischemic preconditioning on the levels of the regulatory α-subuni
Increased survival of embryonic nigral neurons when grafted to hypothermic rats
Hypothermia can reduce neuronal death caused by ischemia and traumatic brain injury. We therefore investigated whether mild hypothermia in rats receiving a transplant of embryonic mesencephalic rat tissue increases survival of the implanted dopaminergic neurons. Mild hypothermia (32-33°C) during graft implantation and for the following 90 min significantly increased the survival of transplanted do
The effect of α-phenyl-tert-butyl nitrone (PBN) on free radical formation in transient focal ischaemia measured by microdialysis and 3,4-dihydroxybenzoate formation
α-phenyl-tert-butyl nitrone (PBN) reduces infarct size, improves recovery of brain energy metabolism and delays the secondary increase in extracellular potassium after focal ischaemia, presumably by trapping OH radicals. We investigated the effect of PBN on the formation of 3,4-dihydroxybenzoic acid (3,4-DHBA) as a measure of OH radical formation, during and following middle cerebral artery occlus
There's more to the multimedia effect than meets the eye : is seeing pictures believing?
Textbooks in applied mathematics often use graphs to explain the meaning of formulae, even though their benefit is still not fully explored. To test processes underlying this assumed multimedia effect we collected performance scores, eye movements, and think-aloud protocols from students solving problems in vector calculus with and without graphs. Results showed no overall multimedia effect, but i
A Subgaleal Hematoma That Turned Out to Be a B-Cell Lymphoma
Background Subgaleal masses are relatively common in the clinical praxis, and after a trauma to the head, a subgaleal hematoma is usually suspected. However, other differential diagnoses, such as malignant tumors, should be kept in mind despite a history of a previous trauma. Case description and Conclusions We report a case of a subgaleal mass that was clinically and radiologically diagnosed as a
A novel RHCE*02 allele, containing the single-nucleotide change c.460A>G, encodes weakened expression of C and e antigens
We report a novel RHCE*02 allele in a Swedish blood donor that is characterized by the change c.460A>G (Arg154Gly). The blood donor's red blood cells showed variable reactivity with different monoclonal anti-C and anti-e and antigen strength was markedly weakened. We believe that these changes represent both a quantitative and qualitative alteration of the antigens encoded by this allele.
Detecting and Communicating archaeology in the Pisa coastal plain : new tools to reach this aim
Versican accumulates in vascular lesions in pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a lethal condition for which there is no effective curative pharmacotherapy. PAH is characterized by vasoconstriction, wall thickening of pulmonary arteries, and increased vascular resistance. Versican is a chondroitin sulfate proteoglycan in the vascular extracellular matrix that accumulates following vascular injury and promotes smooth-muscle cell prolife
New method to quantify contribution to aerosol particles from new particle formation : Comparison with traditional method at Vavihill background field station in Sweden
Aerosol particles exist in the atmosphere in large concentrations and have significant global climate effects. New particle formation is an aerosol particle source and, to date, its contribution to the total aerosol concentration in the atmosphere is not fully understood. This study focuses on the extension of new particle formation events that begin in Lille Valby, Denmark and travel over 70 km t
Kultur för regional utveckling
Play a Game, Save the Planet! Gamification as a Way to Promote Green Consumption
Circulating Osteopontin and Prediction of Hepatocellular Carcinoma Development in a Large European Population
We previously identified osteopontin (OPN) as a promising marker for the early detection of hepatocellular carcinoma (HCC). In this study, we investigated the association between prediagnostic circulating OPN levels and HCC incidence in a large population-based cohort. A nested case-control study was conducted within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. D
Kulturpolitik, styrning och legitimitet i svenska regionala kulturplaner
No title
Fresh banana pseudo-stems as a tropical lignocellulosic feedstock for methane production
The banana pseudo-stem is a low-lignin-content lignocellulosic biomass that can be used for methane production. In recent years, anaerobic digestion (AD) of dried banana stems for methane production has attracted considerable attention. However, there is limited information regarding methane production from the fresh banana pseudo-stem. The direct usability of fresh banana stems as a resource for
Off-label use of rituximab for systemic lupus erythematosus in Europe
Objectives: Rituximab (RTX) is a biological treatment used off-label in patients with systemic lupus erythematosus (SLE). This survey aimed to investigate the off-label use of RTX in Europe and compare the characteristics of patients receiving RTX with those receiving conventional therapy. Methods: Data on patients with SLE receiving RTX were taken from the International Registry for Biologics in
Suicidality and symptoms of anxiety, irritability, and agitation in patients experiencing manic episodes with depressive symptoms : A naturalistic study
Purpose: Patients with a bipolar I disorder (BD-I) manic episode meeting the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5), criteria for "with mixed features" have a high incidence of suicide attempts and of anxiety, irritability, and agitation (AIA) symptoms. The aim of this analysis was to explore the relationship between suicidality and AIA symptoms in patients wi
Meeting Places & Arenas for Local Entrepreneurship : Creative space making in Frederikshavn, north Denmark
Cost-effectiveness and cost-utility analyses of hospital-based home care compared to hospital-based care for children diagnosed with type 1 diabetes; a randomised controlled trial; results after two years' follow-up
Background: Practices regarding hospitalisation of children at diagnosis of type 1 diabetes vary both within countries and internationally, and high-quality evidence of best practice is scarce. The objective of this study was to close some of the gaps in evidence by comparing two alternative regimens for children diagnosed with type 1 diabetes: hospital-based care and hospital-based home care (HBH