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The automated computation of tree-level and next-to-leading order differential cross sections, and their matching to parton shower simulations

We discuss the theoretical bases that underpin the automation of the computations of tree-level and next-to-leading order cross sections, of their matching to parton shower simulations, and of the merging of matched samples that differ by light-parton multiplicities. We present a computer program, MadGraph5 aMC@NLO, capable of handling all these computations - parton-level fixed order, shower-mat

Discursive Constructions of White Nordic Masculinities in Right-wing Populist Media

Using superordinate intersectionality as a theoretical framework, this article explores notions of men and masculinities within right wing populism. It is attentive to how the right-wing populist media in Finland and Sweden construct white Nordic masculinities through discursive interactions across several axes of difference: gender (masculinities); sexuality (heterosexuality); social class (elite

Vocal iconicity in nominal classification

While recent years have seen a substantial increase of studies investigating vocal iconicity in the lexicon of spoken languages, its presence in grammatical structures is poorly understood. This study investigates the presence of vocal iconicity in nominal classification systems by collecting nominal classification devices from the two main system types: 210 non-agreeing languages (126 families) a

Primary prophylaxis in children with severe haemophilia A and B-Implementation over the last 20 years as illustrated in real-world data in the PedNet cohorts

INTRODUCTION: The prophylactic regimen in children with severe haemophilia is suggested in various publications and guidelines. Few data exist on its implementation in clinical practice.AIM: To investigate the implementation of primary prophylaxis based on real-life data from PedNet during the last 20 years.METHODS: All children from the PedNet cohort (n = 1260) with severe haemophilia A (SHA) or

Combining pharmacophore models derived from DNA-encoded chemical libraries with structure-based exploration to predict Tankyrase 1 inhibitors

DNA-encoded chemical libraries (DECLs) interrogate the interactions of a target of interest with vast numbers of molecules. DECLs hence provide abundant information about the chemical ligand space for therapeutic targets, and there is considerable interest in methods for exploiting DECL screening data to predict novel ligands. Here we introduce one such approach and demonstrate its feasibility

Socio-economic status and the rise of divorce in Sweden: The case of the 1880–1954 marriage cohorts in Västerbotten

An established negative association between socio-economic status (SES) and divorce has applied to most Western nations since 1960. We expected a positive association between SES and divorce for low-divorce contexts historically because only individuals in higher social strata had the resources to overcome barriers to divorce. According to Goode’s socio-economic growth theory, this relationship wa

The determinants of AI innovation across European firms

Using patent data for a panel sample of European companies between 1995 and 2016 we explore whether the inventive success in Artificial Intelligence (AI) is related to earlier firms’ innovation in the area of Information and Communication Technology (ICT), and identify which company characteristics and external factors shape this performance. We show that AI innovation presents strong dynamic retu

Starch intake, amylase gene copy number variation, plasma proteins, and risk of cardiovascular disease and mortality

BACKGROUND: Salivary amylase, encoded by the AMY1 gene, initiate the digestion of starch. Whether starch intake or AMY1 copy number is related to disease risk is currently rather unknown. The aim was to investigate the association between starch intake and AMY1 copy number and risk of cardiovascular disease (CVD) and mortality and whether there is an interaction. In addition, we aim to identify CV

Charge and zeta-potential distribution in starch modified with octenyl succinic anhydride (OSA) determined using electrical asymmetrical flow field-flow fractionation (EAF4)

Starch modified with octenyl succinic anhydride (OSA) is extensively used due to its emulsifying capacity. Modification with OSA renders the starch surface active but also anionic at intermediate pH. The amount of OSA that is grafted to the starch polymer backbone will influence the functionality. Likewise, it can be expected that the distribution of the substituents over the molar mass distributi

Novel methodology for the evaluation of symptoms reported by patients with newly diagnosed atrial fibrillation : Application of natural language processing to electronic medical records data

Introduction: Understanding symptom patterns in atrial fibrillation (AF) can help in disease management. We report on the application of natural language processing (NLP) to electronic medical records (EMRs) to capture symptom reports in patients with newly diagnosed (incident) AF. Methods and Results: This observational retrospective study included adult patients with an index diagnosis of incide

Cultural Adaptation of Interventions and the a Priori Assessment of Intervention Fit : Exploring Measurement Invariance for American and Swedish Youth Leaving Care

Purpose: There is a growing literature on the importance of cultural adaptation of research-supported social work interventions. Few studies have however offered systematic methods for the a priori assessment of intervention fit in a new context. The current study explores the use of measurement invariance analyses to help identify whether key theoretical constructs in an intervention’s theory of

Transformative innovation policy–lessons from the innovation system literature

This paper criticizes attempts to present narrow perspectives on innovation policy as reflecting the use of the concept innovation system. While it is correct that innovation policy, at least until recently, has given higher priority to economic growth than to global challenges such as climate change and income inequality this is in no way immanent in the innovation system concept. To illustrate,

Enhanced Temperature Stratification with Deflectors Laid within the Horizontal Water Storage Tank

In the passive solar water heater, temperature stratification is a valuable thermodynamic parameter for horizontal water storage tanks. This investigation aims to optimize the deflector and numerically study the effects of various deflector lengths and materials on temperature stratification of a horizontal water storage tank during natural convection. Firstly, comparative thermal performances of

Upper airway microbiome transplantation for patients with chronic rhinosinusitis

Background: Chronic or recurrent rhinosinusitis without polyps (CRSsNP) is characterized by a persistent inflammation of the sinonasal mucosa. The underlying cause is unclear but increasing interest has been directed toward changes in the sinonasal microbiome as a potential driver. Methods: Twenty-two patients diagnosed with CRSsNP were treated with antibiotics for 13 days, followed by 5 consecuti

Should Benzodiazepines be Used for Reducing Dyspnea in Patients with Advanced Illnesses?

Dyspnea is a common and highly distressing symptom in patients with advanced illnesses. Many patients continue to experience chronic dyspnea despite optimal management of underlying disease(s) and various non-pharmacologic interventions, necessitating the consideration of pharmacologic therapies for palliation of dyspnea. One commonly asked question by clinicians is whether benzodiazepines have a

Mapping trait versus species turnover reveals spatiotemporal variation in functional redundancy and network robustness in a plant-pollinator community

Functional overlap among species (redundancy) is considered important in shaping competitive and mutualistic interactions that determine how communities respond to environmental change. Most studies view functional redundancy as static, yet traits within species—which ultimately shape functional redundancy—can vary over seasonal or spatial gradients. We therefore have limited understanding of how

Examining Legitimacy in Government Agencies’ Crisis Communication

Governments exercise power over the public in many ways. One clear example is during societal crises when government agencies engage in purposeful strategic communication, issue restrictions and recommendations, and rely on people’s compliance to reach response objectives and meet needs in society. Here, issues of authority and legitimacy are crucial. In this study, we are interested in how this p

Cooling strategies during neonatal transport for hypoxic-ischaemic encephalopathy

Aim: We reviewed the literature on cooling methods during transport of newborn infants with hypoxic-ischaemic encephalopathy (HIE) born in a non-tertiary centre and transferred to a neonatal intensive care unit for therapeutic hypothermia. Methods: The electronic databases CENTRAL, MEDLINE, Embase, CINAHL, and Scopus were searched from inception up to 8 March 2022 for studies comparing cooling ver

A Kinetic Map of the Influence of Biomimetic Lipid Model Membranes on Aβ42 Aggregation

The aggregation of the amyloid β (Aβ) peptide is one of the molecular hallmarks of Alzheimer’s disease (AD). Although Aβ deposits have mostly been observed extracellularly, various studies have also reported the presence of intracellular Aβ assemblies. Because these intracellular Aβ aggregates might play a role in the onset and progression of AD, it is important to investigate their possible origi