Filtyp
This doctoral thesis aims to investigate and compare conventional drying technologies (freeze-drying and spray drying) to alternative drying technologies for biologics. Vacuum foam-drying was identified as an alternative drying technology for biologics. Vacuum foam-drying is a drying technique that involves solvent removal by evaporation, at lowered pressure and ambient temperatures. Thus, vacuum
Purpose (the aim of the study): There is limited evidence on psychometric properties of EQ-5D-5L among people with osteoarthritis (OA) undertaking non-surgical treatment. The aim of the current study was to evaluate the psychometric properties of the EQ-5D-5L among individuals with knee or hip OA participating in a digitally delivered education and exercise therapy.Methods: Secondary analysis of d
This study compared two different methods, the satellite altimetry-based and DEM (digital elevation model)-based, for estimating lake water volume changes. We focused on 34 lakes in China as the testing sites to compare the two methods for lake water volume changes from 2005 to 2020. The satellite altimetry-based method used water levels provided by the DAHITI (Database for Hydrological Time Serie
In this paper we discuss the pressing need for a just transition in one of our most environmentally and socially problematic contemporary industries: the fashion and textiles industry. We detail the current injustices in the industry, from both environmental and socio-economic standpoints, and then move on to providing some suggestions as to how these entrenched problems with the industry could be
Ethylene is one of the most important products in the emissions-intensive petrochemical industry. Decarbonizing the ethylene industry is thus important for achieving global carbon neutrality. This study is the first to explore future long-term zero-emissions production pathways for the ethylene industry in China, the world's biggest ethylene producer. An optimization model was built in the context
The Swedish retail landscape is currently undergoing a transformative change with increased digitalization and a rapidly growing e-commerce sector, which creates both opportunities and challenges. The development towards omnichannel commerce creates a more complex customer journey and results in complex environmental challenges. E-commerce deliveries to consumers, in particular, pose a complex soc
Objectives: To investigate the influence of genetic factors on persistence with treatment of early RA with MTX monotherapy. Methods: We conducted a genome-wide association study (GWAS) in a sample of 3902 Swedish early-RA patients initiating MTX in DMARD monotherapy as their first-ever DMARD. The outcome, short-and long-Term MTX treatment persistence, was defined as remaining on MTX at 1 and at 3
Background: Dexmedetomidine is a selective alpha-2 agonist with minimal impact on the haemodynamic profile. It is thought to be safer than morphine or stronger opioids, which are drugs currently used for analgesia and sedation in newborn infants. Dexmedetomidine is increasingly being used in children and infants despite not being licenced for analgesia in this group. Objectives: To determine the o
This article provides an introduction to the special issue on Mapping Shia Muslim Communities in Europe.1 With six empirically rich case studies on Shia Muslim communities in various European countries, this issue intends: first, to illustrate the historical developments and emergence of the Shia presence in Europe; second, to highlight the local particularities of the various Shia communities wit
This article discusses the conversion experiences as recalled by Irish women who converted to Islam during the so-called ‘Celtic-Tiger’ period—the years of Ireland’s dramatic economic boom and major socio-cultural transformations between 1995 and 2007. In this period, the increasing religious diversity of Irish society and the decline of the social authority of the Catholic Church facilitated the
The article focuses on a particular type of Islamic marriage, so-called imam marriages, which are not recognised by the Jordanian state but widely practised among and with Syrian refugees since their influx to Jordan in 2011. State institutions and feminist humanitarian organisations advocate a registration of these marriages on the basis of fulfilling UN conventions on gender and human rights pro
Since the outbreak of the Syrian war in 2011, more than 750,000 Syrians (UNHCR, 2018. Fact Sheet. Available from: https://reliefweb.int/report/jordan/unhcr-jordan-factsheet-february-2018 [Accessed 10 September 2018]) found refuge in Jordan. This paper discusses the use of Art as a research tool to examine Syrian women’s narratives of displacement, identity and home. By drawing the contours of thei
Introduction: The aim was to investigate whether the stem cell marker LGR6 has prognostic value in colon cancer, alone or in combination with the prognostic biomarkers CEA and CXCL16. Methods: LGR6 mRNA levels were determined in 370 half lymph nodes of 121 colon cancer patients. Ability to predict relapse after curative surgery was estimated by Kaplan-Meier survival model and Cox regression analys
Introduction: With a rapidly ageing population, the number of distal radius fractures (DRFs) in the elderly will increase dramatically. The aim of this retrospective register study was to examine the 1- and 5-year mortality in DRF patients aged 80 years or more and correlate the overall survival to factors not related to the fracture itself. Material and Methods: Patients aged ≥80 diagnosed with D
Several studies have shown white matter (WM) abnormalities in Alzheimer’s disease (AD) using diffusion tensor imaging (DTI). Nonetheless, robust characterization of WM changes has been challenging due to the methodological limitations of DTI. We applied fixel-based analyses (FBA) to examine microscopic differences in fiber density (FD) and macroscopic changes in fiber cross-section (FC) in early s
