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Influence of wall ribs on the thermal stratification and self-pressurization in a cryogenic liquid tank

Self-pressurization in a cylindrical ribbed tank which is partially filled with liquid hydrogen is investigated numerically under different rib spacing-to-height ratios. The Volume of Fluid (VOF) method is employed as well as a phase change model. Appropriate models are incorporated into the Ansys Fluent by the user-defined functions to carry out the computations. The ribbed surface is modeled as

Operationalization of Three Dimensions of Sexual Orientation in a National Survey of Late Adolescents.

This study investigated three dimensions of sexual orientation-identity, attraction, and behavior-in a national survey of late adolescents. Prevalence rates and the diversity of dimensions of sexual orientation when combined were studied. A representative sample of 3,432 Swedish high school seniors completed an anonymous school-based self-report survey about sexuality, Internet use, and health. Fo

Dynamic Analysis of Gene Expression and Genome-wide Transcription Factor Binding during Lineage Specification of Multipotent Progenitors

We used the paradigmatic GATA-PU.1 axis to explore, at the systems level, dynamic relationships between transcription factor (TF) binding and global gene expression programs as multipotent cells differentiate. We combined global ChIP-seq of GATA1, GATA2, and PU.1 with expression profiling during differentiation to erythroid and neutrophil lineages. Our analysis reveals (1) differential complexity

Restoration of synaptic plasticity in the host striatum: can transplants make it?

Intrastriatal transplantation of dopamine (DA) neurons can restore DA levels in the striatum and improve parkinsonian deficits in experimental studies. However, the mechanisms underlying these effects are poorly understood. Corticostriatal synaptic plasticity represents an important cellular mechanism for information storage and behavioural learning in the brain. This mechanism is defective in Par

A European summertime CO2 biogenic flux inversion at mesoscale from continuous in situ mixing ratio measurements

A regional variational inverse modeling system for the estimation of European biogenic CO2 fluxes is presented. This system is based on a 50 km horizontal resolution configuration of a mesoscale atmospheric transport model and on the adjoint of its tracer transport code. It exploits hourly CO2 in situ data from 15 CarboEurope-Integrated Project stations. Particular attention in the inversion setup

Fermentation of the Straw Material Paja Brava by the Yeast Pichia stipitis in a Simultaneous Saccharification and Fermentation Process

Paja Brava is a native South American grass with a high carbohydrate content. In the current work, the potential of us- ing this feedstock for ethanol production using a simultaneous saccharification and fermentation (SSF) process with the xylose-fermenting yeast Pichia stipitis (Scheffersomyces stipitis) CBS6054 was investigated. The straw material was subjected to SO2 catalyzed steam pretreatmen

Old and very old adults as witnesses: event memory and metamemory

Older people constitute an important category of eyewitnesses. Episodic memory performance in older persons is poorer than in younger adults, but little research has been made on older persons' metacognitive judgments. Since more persons of advanced age will likely be called upon as witnesses in coming years, it is critical to characterize this population's metacognitive abilities. We compared eve

What can aquatic gastropods tell us about phenotypic plasticity? A review and meta-analysis.

There have been few attempts to synthesise the growing body of literature on phenotypic plasticity to reveal patterns and generalities about the extent and magnitude of plastic responses. Here, we conduct a review and meta-analysis of published literature on phenotypic plasticity in aquatic (marine and freshwater) gastropods, a common system for studying plasticity. We identified 96 studies, using

Modeling of Bottle-Brush Polymer Adsorption onto Mica and Silica Surfaces: Effect of Side-Chain Length

Adsorption of a series of charged bottle-brush polymers with side chains of different length on solid surfaces is modeled using a lattice mean-field theory. The bottle-brush polymers are modeled Lis being composed of two types of main-chain segments: charged segments and uncharged segments with ill attached side chain. The composition variable X denotes the percentage of charged main-chain segment

In situ quantification of minor compounds in pressurized carbon dioxide using Raman spectroscopy

In this work, we present an optical approach that allows quantification of compounds dissolved down to a sub 10 ppm (molar) level in supercritical carbon dioxide (scCO(2)) by in situ Raman spectroscopy. The quantification strategy is based on the consideration of Raman signal intensity ratios and of weak Raman signals of CO2. The first measure makes the quantification strategy independent of the r

M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia.

A balanced interaction between dopaminergic and cholinergic signaling in the striatum is critical to goal-directed behavior. But how this interaction modulates corticostriatal synaptic plasticity underlying learned actions remains unclear-particularly in direct-pathway spiny projection neurons (dSPNs). Our studies show that in dSPNs, endogenous cholinergic signaling through M4 muscarinic receptors

Adolescent Health and Adult Labor Market Outcomes

Whereas a large literature has shown the importance of early life health for adult socioeconomic outcomes, there is little evidence on the importance of adolescent health. We contribute to the literature by studying the impact of adolescent health status on adult labor market outcomes using a unique and large-scale dataset covering almost the entire population of Swedish males. We show that most t

Åldrandet och språket : en språkhistorisk analys av hög ålder och åldrande i Sverige cirka 1875–1975

Popular Abstract in SwedishVad är åldrande? När började man över huvud taget tala om ”åldrande”? När fick ordet ”pensionär” den betydelse vi är vana vid idag? I Åldrandet och språket studeras ord och uttryck för att ringa in vad man har menat med hög ålder och åldrande i Sverige under hundraårsperioden mellan 1875 och 1975. Frågor kring hög ålder och åldrande har stor aktualitet idag. I Sverige ocThis thesis analyses how old age and ageing were manifested and understood in Sweden from approximately 1875 to 1975. It thus aims to provide historical background to current debate about for instance the retirement age and how to best care for the elderly. Encyclopaedia entries from both the beginning and the end of this period describe ageing as a medical process of physical decline. Since much