Technoeconomic analysis of T7 RNA polymerase manufacturing in E.coli for South Africa
The enzyme, T7 RNA polymerase (T7 RNAP), is one of the most expensive raw materials required for mRNA vaccine production. As part of establishing South African manufacturing of mRNA vaccine, it is of interest to investigate the feasibility and profitability of South African manufacturing of T7 RNAP. This project scaled up present lab-scale knowledge on T7 RNAP production and used SuperPro design