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Neurodevelopmental difficulties in children with idiopathic clubfoot

Aim: To evaluate neurodevelopmental difficulties in children with idiopathic clubfoot. Method: A cross-sectional study of 106 children (29 females, 77 males; aged 8–10y) with idiopathic clubfoot and 109 age-, sex-, and residential area-parallelized children from the general population. Neurodevelopmental difficulties were assessed using the parent-report Five to Fifteen (FTF) questionnaire. Group

Bayesian Hierarchical modelling of goal side selection in a soccer penalty kicking task.

The present study investigates goal side selection in soccer penalty kicking. Given the task of choosing which side of a soccer goal to best score, participants viewed realistic images of a soccer goal and goalkeeper. The goalkeeper’s position was systematically displaced along the goal line, and the lateral position of the goalmouth was systematically displaced in each image – to simulate changes

Bayes Factors: A ‘re-volution’ in psychology

In psychology, Bayes Factors (BFs) are being increasingly reported as a complement to p-values. However, just as the mindless computation of p-values encourages a simple dichotomization of study results, the mindless computation of BFs with an overemphasis on hypothesis testing detracts from more useful approaches to interpreting study results, such as parameter estimation. BFs may serve to facili

Teaching Bayesian data analysis to psychology students

Bayesian methods of data analysis are increasingly being adopted in psy-chology and across the social sciences. Yet, attempts to teach Bayesian dataanalysis to the psychology students in Lund has met with many challenges.In this talk, I shall lay out the current progression of statistics teaching fromfirst year undergraduate to master level. Recent attempts to introduce Bayesianmethods of data ana

The ELT-MOS (MOSAIC) : Towards the construction phase

When combined with the huge collecting area of the ELT, MOSAIC will be the most effective and flexible Multi-Object Spectrograph (MOS) facility in the world, having both a high multiplex and a multi-Integral Field Unit (Multi-IFU) capability. It will be the fastest way to spectroscopically follow-up the faintest sources, probing the reionisation epoch, as well as evaluating the evolution of the dw

Celiaki som modell för autoimmun sjukdom. Transglutaminas har nyckelroll--stressreaktion sätter fart på ond cirkel

The autoantigen of endomysial antibodies in coeliac disease has been found to be an enzyme, tissue transglutaminase. Zinc inhibits the calcium-dependent activation of this thiol enzyme and also decreases the affinity between transglutaminase and the antibodies. Physiologically, transglutaminases catalyse the formation of bridges between lysine- and glutamine-containing peptides. Theoretically, if

Screening för celiaki kan vara motiverad i högriskgrupper

Celiaki förekommer hos 0,5–1 procent av befolkningen. Majoriteten av dem med celiaki har atypiska symtom och är inte diagnostiserade. Personer med vissa kromosomrubbningar eller annan autoimmun sjukdom och nära släktingar till personer med celiaki tillhör riskgrupper där screening kan rekommenderas. IgA-endomysie- eller IgA-transglutaminasantikroppar har båda hög specificitet och hög sensitivitet Coeliac disease is widespread and occurs in 0.5-1 per cent of the population. Most sufferers show atypical symptoms and might well remain undiagnosed. Endomysial or human transglutaminase autoantibody levels of type IgA can be recommended as screening instruments combined with s-IgA for exclusion of such deficiency. In contrast, there is a high frequency of false-positive IgA gliadin antibody test

Dags att ifrågasätta managementkonsulternas trams

Managementkonsulternas lösningar saknar allt som oftast stabilt stöd i seriös forskning. Det borde egentligen vara högst kontroversiellt att chefer och politiker väljer att följa råden från dessa karriärister med begränsad erfarenhet, skriverJohan Alvehus, lektor vid Lunds universitet.

Social monitoring via close calls in meerkats

Social monitoring of the actions of group members is thought to be a key development associated with group living. Humans constantly monitor the behaviour of others and respond to them in a flexible way depending on past interactions and the current social context. While other primates have also been reported to change their behaviour towards other group members flexibly based on the current state

The impact of p53 function on the metabolic activation of the carcinogenic air pollutant 3-nitrobenzanthrone and its metabolites 3-aminobenzanthrone and N-hydroxy-3-aminobenzanthrone in human cells

The tumour suppressor p53, encoded by TP53, is a key player in a wide network of signalling pathways. We investigated its role in the bioactivation of the environmental carcinogen 3-nitrobenzanthrone (3-NBA)found in diesel exhaust and its metabolites 3-aminobenzanthrone (3-ABA) and N-hydroxy-3-aminobenzanthrone (N-OH-3-ABA) in a panel of isogenic human colorectal HCT116 cells differing only with r

Inhalation and Dermal Uptake of Particle and Gas-phase Phthalates - A Human Exposure Study

Phthalates are ubiquitous in indoor environments, which raises concern about their endocrine disrupting properties. However, studies of human uptake from airborne exposure are limited. We studied the inhalation uptake and dermal uptake by air-to-skin transfer with clean clothing as a barrier of two deuterium-labelled airborne phthalates: particle-phase D4-DEHP (di-(2-ethylhexyl)phthalate) and gas-

A Chinese alligator in heliox : formant frequencies in a crocodilian

Crocodilians are among the most vocal non-avian reptiles. Adults of both sexes produce loud vocalizations known as ‘bellows’ year round, with the highest rate during the mating season. Although the specific function of these vocalizations remains unclear, they may advertise the caller's body size, because relative size differences strongly affect courtship and territorial behaviour in crocodilians

Territorial raven pairs are sensitive to structural changes in simulated acoustic displays of conspecifics

Human language involves combining items into meaningful, syntactically structured wholes. The evolutionary origin of syntactic abilities has been investigated by testing pattern perception capacities in nonhuman animals. New World primates can respond spontaneously to structural changes in acoustic sequences and songbirds can learn to discriminate between various patterns in operant tasks. However

Ravens attribute visual access to unseen competitors

Recent studies purported to demonstrate that chimpanzees, monkeys and corvids possess a basic Theory of Mind, the ability to attribute mental states like seeing to others. However, these studies remain controversial because they share a common confound: the conspecific’s line of gaze, which could serve as an associative cue. Here, we show that ravens Corvus corax take into account the visual acces

Formants provide honest acoustic cues to body size in American alligators

In many vertebrates, acoustic cues to body size are encoded in resonance frequencies of the vocal tract (“formants”), rather than in the rate of tissue vibration in the sound source (“pitch”). Anatomical constraints on the vocal tract’s size render formants honest cues to size in many bird and mammal species, but it is not clear whether this correlation evolved convergently in these two clades, or

Humans recognize emotional arousal in vocalizations across all classes of terrestrial vertebrates: evidence for acoustic universals

Writing over a century ago, Darwin hypothesized that vocal expression of emotion dates back to our earliest terrestrial ancestors. If this hypothesis is true, we should expect to find cross-species acoustic universals in emotional vocalizations. Studies suggest that acoustic attributes of aroused vocalizations are shared across many mammalian species, and that humans can use these attributes to in