Two lesions, actinic keratosis (AK) and squamous cell carcinoma in situ (CIS), are believed to be precursors of squamous cell carcinoma (SCC) of the skin. These lesions can serve as an excellent model system for studying genetic changes associated with the inception of skin SCC. In the present study, five such lesions of the skin, three AKs and two AK+CIS, from three patients were short-term cultu

Thylakoids isolated from tobacco were fragmented by sonication and the vesicles so obtained were separated by partitioning in aqueous polymer two-phase systems. By this procedure, grana vesicles were separated from stroma exposed membrane vesicles. The latter vesicles could be further fractionated by countercurrent distribution, with dextran-polyethylene glycol phase systems, and divided into two

Popular Abstract in Swedish Denna islamologiska avhandling diskuterar och analyserar den islamtolkning som gjorts av den muslimske tänkaren Nurcholish Madjid i Indonesien. Nurcholish ¬ som nyligen dog vid sextisex års ålder - har bidragit till reformeringen av islamiskt tänkande i Indonesien i över trettio år. Hans idéer är starkt påverkade av den lokala indonesiska kontexten, men utgör också en dThis dissertation in the field of Islamic studies offers a critical analysis of Nurcholish Madjid's attempt to interpret Islam within the framework of modern Indonesia. Nurcholish, who recently passed away at the age of sixty-six, had been active in the reform of Islamic thought for over thirty years, and while remaining deeply coloured by the local Indonesian context, was also part of a global an

The main object of materials science and technology is relationships between structure and properties. The practical use of engineering materials also involves consideration of things other than current theories for such relationships. Uncertainties of various kinds prompt reflections on the validity and applications of common practice based on experience. Among other things, this is true for deci

Initial results from the XUV undulator beamline at the 4.5 GeV storage ring DORIS are reported. The beamline consists of three different undulators mounted on a revolver type device and a modified SX-700 plane grating monochromator with a spherical focusing mirror. It covers the spectral range from 50–2000 eV with excellent spectral resolution and high photon flux. In the energy range 400 eV to 1

The novel cytotoxic hexacyclic illudane-illudalane bis-sesquiterpene bovistol (la) was obtained from the basidiomycete Bovista sp. 96042, together with several new sesquiterpenes. la is formed in the fungus by a heteroatom Diels-Alder dimerisation of psathyrellon B (2). (C) 2002 Elsevier Science Ltd. All rights reserved.

Popular Abstract in Swedish Denna avhandling behandlar två ämnen inom trådlös kommunikation: interferens mellan frekvenshoppande (FH) nätverk och fleranvändardiversitet. I arbetet på FH nätverk undersöks ett system där frekvenshopp används för att möjliggöra samtidig tillgång till kanalen för multipla okoordinerade nätverk. Detta åstadkoms genom att frekvenshoppen sker varje gång ett ny paket skaThis thesis deals with two topics in wireless communications: interference between frequency-hopping (FH) networks, and multiuser diversity. The work on FH treats a system where FH is used to provide simultaneous access to the channel for multiple uncoordinated wireless networks. This is achieved by performing frequency hops on a packet-by-packet basis, and letting the sequence of hopping frequen

The mobile phone is one of the most widespread devices with rendering capabilities. Those capabilities have been very limited because the resources on such devices are extremely scarce; small amounts of memory, little bandwidth, little chip area dedicated for special purposes, and limited power consumption. The small display resolutions present a further challenge; the angle subtended by a pixel i

Abstract is not available

Popular Abstract in Swedish Under kvartärtiden (de senaste 2,6 miljoner åren) har istider (glacialer) och mellanistider (interglacialer) avlös varandra. Mellanistider är perioder (ca 10 000 år) mellan istider (ca 100 000 år), vilket innebär att istid varit det normala under kvartärtiden och att Holocene, den istid vi nu lever i, endast representerar ett kortare intervall. Under istiderna täckte inThe aim of this thesis was to reconstruct the glaciodynamics, deglacial landforms, isostatic uplift and to date the deglaciation. Glaciodynamics and deglacial landforms were focused on to provide a process and depositional model for De Geer moraine and Niemisel moraine and to reveal their internal and spatial relationship, based on detailed sedimentological and structural investigations. The isost

Growth of the smooth muscle in the rat portal vein was initiated by an increased transmural pressure. After 7 days, the cross-sectional area of the vessel wall and the maximal active force of the longitudinal muscle layer had increased twofold. Electron microscopy showed that the cell cross-sectional area was increased, suggesting cellular hypertrophy. Increased amounts of intermediate (10 nm) fil

In treatment of Meniére's disease, installations of gentamicin are continued until there are signs of disturbance of vestibular or cochlear function. However, since it has been demonstrated that gentamicin is eliminated slowly from the inner ear, a continuing ototoxic effect may be suspected. The present study aimed to investigate the delay of onset of symptoms of ototoxic effects. Five patients w

Latent autoimmune diabetes in adults (LADA) is a disorder in which, despite the presence of islet antibodies at diagnosis of diabetes, the progression of autoimmune ß-cell failure is slow. LADA patients are therefore not insulin requiring, at least during the first 6 months after diagnosis of diabetes. Among patients with phenotypic type 2 diabetes, LADA occurs in 10% of individuals older than 35

The aim of this prospective longitudinal study was to measure prospectively the bone mineral density (BMD) and anthropometric variables after a hip fracture. In particular, we studied changes in the BMD in both the injured and uninjured hips, and examined if the postoperative mortality rate and complications, including pseudarthrosis of the fracture and late segmental collapse of the head of the f

Objectives. To study the relationship between clinical manifestations in systemic lupus erythematosus (SLE) with polymorphisms in suggested susceptibility genes encoding Fc gamma RIIa, Fc gamma RIIIa, Fc gamma RIIIb, CRP and IL-1Ra. Methods. Genetic polymorphisms were analysed in 323 unrelated SLE patients and 200 healthy blood donors. The genotype frequencies were compared between clinical subset