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Mild traumatic brain injury, such as concussion, was once considered self-resolving. However, over the past decade, increased understanding of the short- and long-term impact has led to new guidelines for active management. In this review, we summarise recent findings, covering diagnostic criteria, and management for early and persistent symptoms. Many of the postconcussive symptoms can be treated

Autoimmune diseases and the risk and prognosis of latent autoimmune diabetes in adults

Aims/hypothesis: The aim of this study was to clarify the impact of autoimmune disease (AD) comorbidity on the risk and prognosis of latent autoimmune diabetes in adults (LADA). Methods: We used data from a Swedish study comprising newly diagnosed cases of LADA (n=586, stratified into LADAlow and LADAhigh by autoantibody levels), type 2 diabetes (n=2003) and matched control participants (n=2355).

The Mantis Network : IV. A titanium cold trap on the ultra-hot Jupiter WASP-121 b

Context. Using emission lines from metals, we investigate the three-dimensional distribution of temperature and chemistry in ultra-hot Jupiters. Aims. Existing observations of WASP-121 b have suggested an underabundance of titanium and titanium oxide in its terminator region. In this study, we aim to determine whether this depletion is global by investigating the dayside emission spectrum. Methods

Best Practice of Peritoneal Dialysis-Associated Gram-Negative Peritonitis in Children : Insights From the International Pediatric Peritoneal Dialysis Network Registry

Introduction: Gram-negative peritonitis (GNP) is associated with significant morbidity in children receiving long-term peritoneal dialysis (PD) and current treatment recommendations are based on limited data. Methods: Analysis of 379 GNP episodes in 308 children (median age 6.9 years, interquartile range [IQR]: 3.0–13.6) from 45 centers in 28 countries reported to the International Pediatric Perit

Successful prevention of organic solvent induced disorders : history and lessons

In this discussion paper, we describe the history of the science and societal action resulting in the mitigation of neurotoxic disorders from exposure to organic solvents at the workplaces in Sweden. When alkyd paints were introduced in large scale in construction painting in the 1960s and 1970s, Scandinavian unions voiced increasing concern as members reported symptoms like headache and vertigo,

Cystektomi för blåscancer – har utfallet förbättrats?

Radical cystectomy (RC) for bladder cancer is a complex procedure with an inherent risk of complications and even postoperative mortality. Historically, RC was performed in 44 hospitals in Sweden, which gradually decreased over time, and since a formal regional centralisation of these operations in 2017, cystectomy care is currently provided by nine hospitals. In the Swedish national urinary bladd

Characteristic Modes and Nonreciprocity

Properties of characteristic modes of lossless scatterers breaking time-reversal symmetry are presented utilizing the scattering formulation of characteristic decomposition. Antennas connected to nonreciprocal circuits and moving material bodies are used as numerical examples.

Population-based Organised Prostate Cancer Testing : Results from the First Invitation of 50-year-old Men

Background: The European Union recently recommended evaluation of the feasibility of organised prostate cancer screening. In Sweden, regional population-based organised prostate cancer testing (OPT) programmes were introduced in 2020. Objective: To describe initial participation rates and diagnostic outcomes. Design, setting, and participants: The three most populated Swedish regions invited all m

‘Say Bible!’: Teaching Biblical Reception

Classes focused on biblical reception might seem to some like a “get out of jail” card in the face of ever-threatening questions about the relevance of biblical studies today. To others, such classes look like a cul-de-sac that fails to lead to either renewed interest in the Bible or meaningful pedagogical outcomes. In this short reflection, I tease out chances and challenges that come with teachi

Talking body : the effect of body and voice anthropomorphism on perception of social agents

Introduction: In human-agent interaction, trust is often measured using human-trust constructs such as competence, benevolence, and integrity, however, it is unclear whether technology-trust constructs such as functionality, helpfulness, and reliability are more suitable. There is also evidence that perception of “humanness” measured through anthropomorphism varies based on the characteristics of

The Bible in the North: Commodity and Content on the Secular Market

Understanding biblical texts in context usually entails an awareness of the times and places in which these texts first emerged and were first encountered. In this article, I aim to make a case for more contextual work on the Bible in the Northern parts of the contemporary world. After discussing contexts in relation to the Bible, I turn to the Global North and questions of secularization, before

Structural change in city systems evolution

This paper analyzes city system dynamics, based on a theoretical framework relating interaction potentials to agglomeration economies and density externalities. It employs new historical time series data on population size of cities in Sweden over two centuries (1810–2010) and introduces two schematic growth factors: (i) the intra-city potential and (ii) the extra-city potential located in in ring

Factor H Binds to the Hypervariable Region of Many Streptococcus pyogenes M Proteins but Does Not Promote Phagocytosis Resistance or Acute Virulence.

Many pathogens express a surface protein that binds the human complement regulator factor H (FH), as first described for Streptococcus pyogenes and the antiphagocytic M6 protein. It is commonly assumed that FH recruited to an M protein enhances virulence by protecting the bacteria against complement deposition and phagocytosis, but the role of FH-binding in S. pyogenes pathogenesis has remained un

Nigral 6-hydroxydopamine lesion impairs performance in a lateralised choice reaction time task-Impact of training and task parameters

Unilateral intrastriatal and intra-medial forebrain bundle injections of 6-OHDA impair the performance in a lateralised choice reaction time task. However, the extent and pattern of deficits after nigral 6-OHDA injections is less well studied, as well as the impact of training regime or the modification of various task parameters. The nigral 6-OHDA lesion resulted in impaired response accuracy and

Greening in the circumpolar high-latitude may amplify warming in the growing season

We present a study that suggests greening in the circumpolar high-latitude regions amplifies surface warming in the growing season (May-September) under enhanced greenhouse conditions. The investigation used a series of climate simulations with the Community Atmospheric Model version 3-which incorporates a coupled, dynamic global vegetation model-with and without vegetation feedback, under both pr

Green-Glued Products for Structural Applications

The results from bending tests on 107 laminated, green-glued, beams manufactured from Norway spruce side boards are presented. The beams were made by face gluing 21-25 mm thick boards using a commercial one-component moisture curing polyurethane adhesive. In addition to the bending test results, results from shape stability measurements after climatic cycling and bond line strength and durabili

Interleaved parton showers and tuning prospects

General-purpose Monte Carlo event generators have become important tools in particle physics, allowing the simulation of exclusive hadronic final states. In this article we examine the PYTHIA 8 generator, in particular focusing on its parton-shower algorithms. Some relevant new additions to the code are introduced, that should allow for a better description of data. We also implement and compare w

Allelic variation at innate immune genes (avian beta-defensins), within a natural population of great tits

In order to fully understand pathogen induced natural variation in fitness in wild animal populations it is important to identify and study the degree of non-synonymous alleles in genes that code for components of the immune system. This study investigates the degree of natural genetic variation at 6 innate immune genes belonging to the -defensin family within a single population of birds, the gre

Impact of urban warming on earlier spring flowering in Korea

Using long-term (1954-2004) observations of four selected species in South Korea: goldenbell (Forsythia koreana), azalea (Rhododendron mucronulatum), cherry (Prunus yedoensis), and peach (Prunus persica), the impact of urban warming on spring flowering was investigated. Trends of early spring temperatures and first-flowering dates (FFDs) of the four plants were cross-compared among nine differentl

Quantitative Proteomic Analysis of Eight Cartilaginous Tissues Reveals Characteristic Differences as well as Similarities between Subgroups.

Human synovial joints display a characteristic anatomic distribution of arthritis e.g. rheumatoid arthritis primarily affects the metacarpophalangeal and proximal finger joints, but rarely the distal finger joints, while osteoarthritis occur in the distal and proximal finger joints. Pelvospondylitis has a selective localization to the spine and sacroiliac joints. Is this tropism due to differences