Popular Abstract in Swedish Tumörer kan på olika sätt hämma immunsystemet och detta kan vara orsaken till varför immunterapi mot tumörer oftast inte lyckas. Denna nedreglering av immunförsvaret kan medieras av faktorer producerade från tumörcellerna själva eller så kan den följa efter en stark immunstimulering som satts igång av immunterapi. Kväve monoxid (NO) har visats vara en av de ämnen som kaDuring tumor progression a strong immunosuppression is developed and is believed to be the major reason why immunotherapy fails. This suppression is induced in response to factors produced from tumor cells, but can also be induced after immunotherapy. NO has been shown to play a major role in this suppression both in patients with gliomas and colon carcinomas. The aim of this thesis is to clarify

Short essay on My man Godfrey (1936)

In clinical transplantation immunosuppressive agents are used in combination with the objective to achieve additive effects and less toxicity. A large number of novel drugs are candidates for clinical introduction at this time and experiments in animal models have an important role to play. The aim of this study was in brief to evaluate the capacity to inhibit the acute rejection process with biol

Existential biography does not so much search for a logical development in a person’s life as for the opportunities to shape and choose between different paths. Instead of using identities, which are often ambiguous in the extreme, I follow the Swedish historian Henrik Rosengren in his use of different cultural identifications that together form an identity. Identifications are changeable and mani

This paper reports on an inquiry into the use of metadata, publishing formats, and markup in editor-managed open access journals. It builds on findings from a study of the document architectures of open access journals, conducted through a survey of 265 journal web sites and a qualitative, descriptive analysis of 4 journal web sites. The journals’ choices of publishing formats and the consistency

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Popular Abstract in Swedish Den främsta orsaken till att cancer kan leda till döden är att tumörceller växer in i angränsande vävnad (invasiv) och tar sig in i blodet eller lymfsystemet och på så sätt sprids (metastaserar) till andra ställen i kroppen och stör funktionen i livsviktiga organ dvs tumören får ett aggressivt växtsätt. Det är därför viktigt, både ur prognostisk och terapeutisk synvinkeThe progressive process of tumour invasion and generation of metastases is the primary cause of death for most patients with cancer. Some of the regulatory components of this progressive process are adhesion, migration, and proteolysis. Urokinase -type plasminogen activator (u-PA) is a serine protease associated with tissue remodelling, cellular invasiveness, matrix degradation, angiogenesis, and

Vitamin D was discovered due to its ability to cure rickets, but recently many other important functions for it in the human body have been discoverred, and it counteracts several other diseases, as diabetes and some forms of cancer. The nuclear vitamin D receptor has been found throughout the vertebrate phylum down to jawless fishes, but not in invertebrates. Its role in those organisms that are