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Writing write-downs : the rhetoric of goodwill impairment

PurposeThe aim of this paper is to study the rhetoric of goodwill impairment, more specifically rhetoric, as it is constructed in the form of accounts (i.e. statements that explain unanticipated or untoward behavior). The authors argue that goodwill impairment is not only a technical matter but also a rhetorical practice by means of which external scrutiny is responded to.Design/methodology/approa

Short-term organ dysfunction is associated with long-term (10-Yr) mortality of septic shock

Objectives: As mortality of septic shock decreases, new therapies focus on improving short-term organ dysfunction. However, it is not known whether short-term organ dysfunction is associated with long-term mortality of septic shock. Design: Retrospective single-center. Setting: Mixed medical-surgical ICU. Patients: One thousand three hundred and thirty-one patients with septic shock were included

Independent and Wistful

Panel 20 - Collaboration in New Configurations: Ethnologists’ Teaching and Research in Multidisciplinary SettingsIn this presentation I would like to talk about the feelings that multidisciplinary work may evoke. When an ethnologist leaves the mothership, the department of Ethnology, and seeks new ways, a feeling of homesickness is likely to emerge, notwithstanding the free choice. In a new interd

Across all Borders : An Investigation into Radio Activities and the Scandinavian Media Model in 1959

“Across all borders”: An investigation into media activities and the Scandinavian Media Model in 1959In this case study we are going to investigate two different radio productions that in interesting ways were crossing the geographical borders between the countries Sweden and Norway and between Sweden and Denmark in the year of 1959. Through the concepts of border (see Hurd et al. 2006) showing ho

Pedestrian planning and the challenges of instrumental rationality in transport planning: emerging strategies in three Swedish municipalities

Despite having been subject to a strong and many-sided critique, instrumental rationality persists as paramount in transport planning practice and research. This paper argues that it is crucial to acknowledge the prescriptive and normative facet of instrumental rationality in order to understand its impact on transport planning. The aim is to explore to what extent pedestrian planning – within a s

Anion-conducting polysulfone membranes containing hexa-imidazolium functionalized biphenyl units

Poly(arylene ether sulfone)s containing randomly distributed biphenyl units tethered with precisely six imidazolium cations are designed and prepared with the aim to facilitate ionic clustering and conductivity of anion exchange membranes (AEMs). A series of statistical copolymers with different cationic contents are synthesized via K2CO3-mediated polycondensations of 2,2′,3,3′,5,5′-hexamethyl-4,4

No title

Abstract in French:Cet article propose une synthèse des résultats d'un projet de recherches sur le développement du français par des enfants L2 (L1 suédois) dont l'âge de début d'acquisition (ÂdA) varie entre 3;5 ans et 6;5 ans. Nous résumons les résultats principaux sur différentes structures grammaticales, notamment la finitude, les objets clitiques, le genre, l'accord sujet-verbe et les formes

Physical inactivity during leisure time and irregular meals are associated with functional gastrointestinal complaints in middle-aged and elder subjects

Objectives: Few studies have examined how lifestyle factors affect functional gastrointestinal disorders. The aim of this study was to see if leisure time physical inactivity, dietary habits or body mass index (BMI) were associated with increased risk of functional abdominal pain, functional bloating, functional constipation or functional diarrhea. Methods and materials: This study was based on a

Interacting factors associated with Low antibiotic prescribing for respiratory tract infections in primary health care - A mixed methods study in Sweden

Background: Prescribing of antibiotics for common infections varies widely, and there is no medical explanation. Systematic reviews have highlighted factors that may influence antibiotic prescribing and that this is a complex process. It is unclear how factors interact and how the primary care organization affects diagnostic procedures and antibiotic prescribing. Therefore, we sought to explore an

"Vi har redan tillräckligt med judar här” : tonsättaren Hans Holewa och exilens dubbelhet

Tonsättaren, radiomedarbetaren och musikern Hans Holewa (1905–1991) anlände till Sverige 1937 som landsflyktig undan den tilltagande antisemitismen i Wien, drygt ett halvår innan Österrike annekterades av Nazityskland. Som invandrad radikal tonsättare med den så kallade tolvtonstekniken som utgångspunkt, med judiskt påbrå och med engagemang inom vänsterrörelsen kom Holewas svenska exiltillvaro utg

Myo-inositol changes precede amyloid pathology and relate to APOE genotype in Alzheimer disease

Objective: We aimed to test whether in vivo levels of magnetic resonance spectroscopy (MRS) metabolites myo-inositol (mI), N-acetylaspartate (NAA), and choline are abnormal already during preclinical Alzheimer disease (AD), relating these changes to amyloid or tau pathology, and functional connectivity. Methods: In this cross-sectional multicenter study (a subset of the prospective Swedish BioFIND

Prefermentation improves ethanol yield in separate hydrolysis and cofermentation of steam-pretreated wheat straw

Agricultural residues, such as wheat straw, are feasible substrates for ethanol fermentation provided that pentoses and hexoses can be converted efficiently. Separate hydrolysis and cofermentation (SHCF) constitute a framework for improvement of conversion efficiency, because it permits independent optimization of the enzymatic hydrolysis and cofermentation steps. A drawback is that the high gluco

The 3-D Structural Basis for the Pgi Genotypic Differences in the Performance of the Butterfly Melitaea cinxia at Different Temperatures

Although genotype-by-environment interaction has long been used to unveil the genetic variation that affects Darwinian fitness, the mechanisms underlying the interaction usually remain unknown. Genetic variation at the dimeric glycolytic enzyme phosphoglucoisomerase (Pgi) has been observed to interact with temperature to explain the variation in the individual performance of the butterfly Melitaea

Experimental Active-Site Mapping by Fragments - Hot Spots Remote from the Catalytic Center of Endothiapepsin

Successful optimization of a given lead scaffold requires thorough binding-site mapping of the target protein particular in regions remote from the catalytic center where high conservation across protein families is given. We screened a 361-entry fragment library for binding to the aspartic protease endothiapepsin by crystallography. This enzyme is frequently used as surrogate for the design of re

Structures of endothiapepsin-fragment complexes from crystallographic fragment screening using a novel, diverse and affordable 96-compound fragment library

Crystallographic screening of the binding of small organic compounds (termed fragments) to proteins is increasingly important for medicinal chemistry-oriented drug discovery. To enable such experiments in a widespread manner, an affordable 96-compound library has been assembled for fragment screening in both academia and industry. The library is selected from already existing protein-ligand struct