Renal impairment after hip or knee arthroplasty. Urinary excretion of protein markers studied in 59 patients
We studied renal function during and after surgery in 38 patients undergoing total hip replacement (THR) and 21 patients undergoing total knee replacement (TKR). Serum creatinine and renal excretion of albumin, IgG, protein HC and creatinine were recorded preoperatively and on days 1, 2, 4, and 8, THR patients were randomized to treatment with (n 17) or without (n 21) prophylactic isoxazolyl penic