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A 76-year-old male was diagnosed to have diabetes mellitus at 57 years of age and oral hypoglycemic agents were started. Aspart, a human insulin analogue, was initiated because of a poor glycemic control in July 2009, at 74 years of age. He complained of dizziness and faintness caused by hypoglycemia in the early morning and afternoon. He was admitted to another hospital in August 2010; his plasma
Increasing evidence indicates that phospholipid oxidation plays important roles in atherosclerosis. Here, we investigated the involvement of Rho-family GTPases inphosphatidylcholine hydroperoxide (PCOOH)-induced THP-1 cell adhesion to ICAM-1. Isoprenoid depletion by fluvastatin and geranylgeranyltransferase inhibition by GGTI-286 suppressed PCOOH-induced cell adhesion to ICAM-1 and F-actin-rich me
Aim: We investigated how dietary management affected body weight (BW) reduction and energy expenditure in obese and normal-weight type 2 diabetic patients. Methods: Type 2 diabetic patients who were hospitalized for diabetic control (93 men and 51 women) were checked for resting energy expenditure (REE). Subjects were divided into the two groups according to body mass index (BMI): obese (BMI ≥ 25)
Insulin tolerance test (ITT) is the gold standard for assessing the hypothalamic-pituitary-adrenal (HPA) function. GH-releasing peptide (GHRP)-2, which has a strong GH-stimulating activity, is useful for diagnosing GH deficiency as well as ITT. Additionally, GHRP-2 is also known to activate HPA axis. There have been no comparative studies of pituitary-adrenal responsiveness between GHRP-2 test and
Aims: The atherogenicity of chylomicron remnants has been discussed. We examined whether serum apoB48 level is associated with the presence of carotid plaque in type 2 diabetic patients. Method: Forty type 2 diabetic patients (21 males and 19 females, 52.8 ± 11.8 years old; mean ± S.D.) were divided into two groups by the presence or absence of carotid plaque. The diurnal change of serum apoB48 le
In her dissertation Aspektuella hjälpverb i svenskan, Maria Bylin investigates the evolution of six aspectual auxiliaries in Swedish (bruka ‘use to’, tendera ‘tend to’, börja ‘begin’, fortsätta ‘continue’, sluta ‘stop’ and hota ‘threaten’). The study is conducted within the framework of grammaticalization, and Bylin’s primary method is to apply so-called auxiliary tests on a historical material co
This paper investigates restrictions on the reported possibility to extract from adjunct clauses in Swedish. I report results from an acceptability judgement study showing that extraction is constrained by the following factors: (i) the degree of syntactic integration of the adjunct clause, (ii) the internal syntax of the adjunct clause, and (iii) semantic coherence. Regarding factor (i), extracti
Vitamin D insufficiency is common, correctable, and influenced by genetic factors, and it has been associated with risk of several diseases. We sought to identify low-frequency genetic variants that strongly increase the risk of vitamin D insufficiency and tested their effect on risk of multiple sclerosis, a disease influenced by low vitamin D concentrations. We used whole-genome sequencing data f
The aim of this study is to explore the possibility of identifying speaker stance in discourse, provide an analytical resource for it and an evaluation of the level of agreement across speakers in the area of stance-taking in discourse. We explore to what extent language users agree about what kind of stances are expressed in natural language use or whether their interpretations diverge. In order
The Scandinavian heart transplant everolimus de novo study with early calcineurin inhibitors avoidance (SCHEDULE) trial was a 12 month, randomized, open-label, parallel-group trial that compared everolimus (EVR; n=56) to conventional CsA (n=59) immunosuppression. Previously, we reported that EVR outperformed CsA in improving renal function and coronary artery vasculopathy, despite a higher rejecti
Presently, there is no single, coherent theory on the causality between cities and economic growth, only a fragmented set of theories. Current patterns and trends for the relationship between cities and economic growth, however, suggest that a full understanding of contemporary processes will not be achieved by relying on the tools of one discipline alone, or by focusing on a single level of analyPresently, there is no single, coherent theory on the causality between cities and economic growth, only a fragmented set of theories. Current patterns and trends for the relationship between cities and economic growth, however, suggest that a full understanding of contemporary processes will not be achieved by relying on the tools of one discipline alone, or by focusing on a single level of analy
Why are female children still at risk in India despite progress in education, increasing participation of women in economic and political activities, and an overall improvement in the status of women? Is there any significant shift from 'son preference' to 'daughter discrimination'? Based on a study of two villages from low-fertility regions of Karnataka and Tamil Nadu, this paper attempts to unde
The importance of school climate in schooling has been demonstrated consistently over the last 50 years. In this study, we investigate how individual student norms and opinions shape and affect school climate. Through the use of secondary survey data collected within two research projects at eight schools throughout Sweden in two different years, we demonstrate how individual student norms develop
