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Abnormal cerebral hemodynamics and blood-brain barrier permeability detected with perfusion MRI in systemic lupus erythematosus patients

Objective: Dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI) has previously shown alterations in cerebral perfusion in patients with systemic lupus erythematosus (SLE). However, the results have been inconsistent, in particular regarding neuropsychiatric (NP) SLE. Thus, we investigated perfusion-based measures in different brain regions in SLE patients with and without NP invo

Unsettled City: Neoliberal redevelopment, state crisis, slum resettlement & biopolitical struggle in Mumbai

Denna avhandling handlar om kapitalistisk stadsförnyelse och regleringen av bostadsfattigdom i Mumbai. Avhandlingen undersöker hur stadsutvecklingsregimer formar omflyttningar och styrning av befolkningen i Mumbai. Författaren använder etnografiskt utforskande av två storskaliga projekt: transportexpansion och pipelinesäkerhet samt två omlokaliserade samhällen och deras socio-politiska dynamik på This dissertation concerns capitalist urban redevelopment and the government of urban housing poverty. It examines the ways urban redevelopment regimes shape resettlements and governance of urban populations in Mumbai. The specific enquiries focus on salient accumulative and dispossessive dimensions of urban redevelopment and linked resettlement construction, the reformation of informal politics o

Lovisa Ulrikas akademi : Sveriges första vittra kungliga akademi

Lovisa Ulrikas kulturella och politiska bakgrund skildras, liksom hennes personliga förutsättningar för att befrämja litteratur, konst och vetenskap. Hennes bildande av Vitterhetsakademien 1753 beskrivs, dess verksamhet och dess fortsättning i Svenska akademien (1786) beskrivs.

To Accompany, Always : Psychological Elements of Palliative Care for the Dying Patient

Palliative care clinicians provide psychological support throughout their patients' journeys with illness. Throughout our series exploring the psychological elements of palliative care (PEPC), we suggested that the quality of care is enhanced when clinicians have a deeper understanding of patients' psychological experience of serious illness. Palliative care clinicians are uniquely poised to offer

Turning the Lens Inward : The Psychological Elements of Clinician Well Being

This is the seventh entry in the Psychological Elements of Palliative Care (PEPC) series. Previous articles have focused on the psychological elements of the care we provide patients and the relationships we build with our referring clinician colleagues. In this entry, we focus on how the PEPC also impact clinician well being. The PEPC are bidirectional: we impact patients, but patients also impac

Development of a Prognostic Awareness Impact Scale for Patients with Advanced Cancer

Background: No reliable instruments exist to measure prognostic awareness and its psychological and behavioral impacts for patients with advanced cancer. Methods: We developed the Prognostic Awareness Impact Scale (PAIS) using a qualitative approach. During phase 1, we convened a working group with a transdisciplinary team of clinicians from oncology (n = 2), psychology (n = 2), psychiatry (n = 1)

Randomized Trial of a Palliative Care Intervention to Improve End-of-Life Care Discussions in Patients With Metastatic Breast Cancer

Background: Studies show that early, integrated palliative care (PC) improves quality of life (QoL) and end-of-life (EoL) care for patients with poor-prognosis cancers. However, the optimal strategy for delivering PC for those with advanced cancers who have longer disease trajectories, such as metastatic breast cancer (MBC), remains unknown. We tested the effect of a PC intervention on the documen

Referral Relationship : Illuminating the Ways Palliative Care Creates a Holding Environment for Referring Clinicians

Palliative care supports referring colleagues in multiples ways. This support to referring colleagues is not often explored in the literature, yet the psychological concept that best describes it is the holding environment. The holding environment is the relational space palliative care offers referring clinicians for processing emotions and information. Using the case of Gloria, a patient living

Patient Perspectives on Serious Illness Conversations in Primary Care

Background: The Serious Illness Care Program has been shown to improve quality and feasibility of value-based end-of-life conversations in primary care. Objectives: To elicit patients' perspectives on serious illness conversations conducted by primary care clinicians. Subjects and Methods: Telephone interviews were conducted with patients at an academic center in the United States, who had a recen

Adapting the serious illness conversation guide for use in the emergency department by social workers

Objective Although important treatment decisions are made in the Emergency Department (ED), conversations about patients’ goals and values and priorities often do not occur. There is a critical need to improve the frequency of these conversations, so that ED providers can align treatment plans with these goals, values, and priorities. The Serious Illness Conversation Guide has been used in other c

Assessing the Acceptability and Feasibility of Leveraging Emergency Department Social Workers' Advanced Communication Skills to Assess Elderly Patients' Goals and Values

Background: The Emergency Department (ED) has increasingly been recognized as an important site of care for older adults with unmet palliative care needs. Despite this, no clear model of care delivery has emerged. Aim: To assess the acceptability and feasibility of a scripted palliative care communication intervention in the ED directed by social workers. We hypothesized that the intervention woul

(Don't) Leave Me Alone : Attachment in Palliative Care

This is the fifth article in the psychological elements of palliative care series. This series focuses on how key concepts from psychotherapy can be used in the context of palliative care to improve communication and fine tune palliative care interventions. In this article, we discuss attachment - the system by which people form bonds in relationships. The different styles that people have in navi

Improving Serious Illness Communication : Testing the Serious Illness Care Program with Trainees

Background: Early conversations about patients’ goals and values improve care, but clinicians struggle to conduct them. The systems-based Serious Illness Care Program (SICP) helps clinicians have more, better, and earlier conversations. Central to this approach is a clinician conversation guide for patient encounters. While the SICP works for practicing clinicians, it has not been tested with medi

The meaning of together : Exploring transference and countertransference in palliative care settings

Establishing an empathic clinical relationship is a cornerstone of high-quality palliative care. More than simply approaching patients with a pleasant affect or "being nice,"we propose that skilled clinicians routinely employ distinct psychological elements when creating effective bonds with seriously ill patients and their families. Palliative care involvement has been shown to improve a variety

Stable incidence but increase in prevalence of ANCA-associated vasculitis in southern Sweden: a 23-year study

Objective To update the epidemiology of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) in a defined geographical area of southern Sweden.Methods The study area comprised 14 municipalities with a combined adult population (≥18 years) of 623 872 in 2019. All cases diagnosed with AAV in 1997–2019 in the study area were included in the estimate of incidence. Diagnosis of AAV was veri