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Microarray-based cancer diagnosis with artificial neural networks

In recent years, the advent of experimental methods top robe gene expression profiles of cancer on a genome-wide scale has led to widespread use of supervised machine learning algorithms to characterize these profiles. The main applications of these analysis methods range from assigning functional classes of previously uncharacterized genes to classification and prediction of different cancer tiss

Simulations of flow around a confined oscillating circular cylinder using a virtual boundary method

In this paper streamwise and transverse oscillations of a rigid circular cylinder in a rectangular channel are investigated using the Virtual Boundary method. Numerical study of the three-dimensional flow around the cylinder is done for the uniform Cartesian grid. All computations are performed at Reynolds numbers of Re=500 and 1000 based on the mean flow velocity. The Keulegan-Carpenter number (K

A study of the inner-valence ionization region in HCl and DCl

An in-depth photoionization study of the inner-valence electrons in HCl and DCl has been performed using synchrotron radiation. A series of photoelectron spectra of HCl were obtained at a resolution of 23 meV over the binding energy range 25-30.5 eV at various excitation energies and at two different electron collection angles relative to the plane of polarization of the undulator radiation. In ad

Garner and Congruence Effects in the Speeded Classification of Bimodal Signals

The role of attention in speeded Garner classification of concurrently presented auditory and visual signals was examined in 4 experiments. Within-trial interference (i.e., congruence effects) occurred regardless of the attentional demands of the task. Between-trials interference (i.e., Garner interference) occurred only under conditions of divided attention when making judgments about auditory si

Statistical rate allocation for layered space-time structure

We propose a modified layered structure for multiple-input multiple-output systems, where the layer detection order is fixed and the data rate for each layer is allocated based on the detection order and channel statistics. Using a Gaussian approximation of the layer capacities, we derive an asymptotic optimum data-rate-allocation approach. For optimum data-rate allocation, the amount of backoff f

Age-related changes in P wave morphology in healthy subjects.

Background We have previously documented significant differences in orthogonal P wave morphology between patients with and without paroxysmal atrial fibrillation (PAF). However, there exists little data concerning normal P wave morphology. This study was aimed at exploring orthogonal P wave morphology and its variations in healthy subjects. Methods 120 healthy volunteers were included, evenly di

Radiative lifetime measurements and transition probability calculations in lanthanide ions

We have undertaken a systematic investigation of spectroscopic properties of lanthanide ions (Z=57-71). Using time-resolved laser-induced fluorescence following one- or two-photon excitations, a large number of radiative lifetimes have been measured at the Lund Laser Centre for singly, doubly and trebly ionized atoms. These new measurements have been used for testing theoretical calculations perfo

Water dimer in solid neon. Far-infrared spectrum

Infrared spectra of water and deuterated water isolated in neon matrices have been recorded between 20 and 5000 cm(-1). The water concentration has been varied between very low concentrations with only monomers present up to concentrations where pentamers and possibly hexamers are present in significant amounts. The concentration dependencies of the observed absorption bands have been used to assi

Sick leave among home-care personnel: a longitudinal study of risk factors

Background Sick leave due to neck, shoulder and back disorders (NSBD) is higher among health-care workers, especially nursing aides/assistant nurses, compared with employees in other occupations. More information is needed about predictors of sick leave among health care workers. The aim of the study was to assess whether self-reported factors related to health, work and leisure time could predict

Clinical features of achromatopsia in Swedish patients with defined genotypes.

Purpose: To describe the clinical phenotype, with emphasis on the electrophysiological findings, of patients with autosomal recessive rod monochromacy (RM) and defined mutations in the CNGA3/CNGB3 genes. Methods: RM patients from eight different families were included in the study. Their genotypes were determined by DNA sequencing and/or RFLP analysis of PCR-amplified genomic segments of the CNGA3

An evolutionary analysis of the aetiology and pathogenesis of juvenile-onset myopia

The available evidence suggests that both genes and environment play a crucial role in the development of juvenile-onset myopia. When the human visual system is examined from an evolutionary perspective, it becomes apparent that humans, living in the original environmental niche for which our species is genetically adapted (as hunter-gatherers), are either slightly hypermetropic or emmetropic and