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CD163+ macrophages in mantle cell lymphoma induce activation of prosurvival pathways and immune suppression

Mantle cell lymphoma (MCL) is dependent on a supportive tumor immune microenvironment (TIME) in which infiltration of CD163+ macrophages has a negative prognostic impact. This study explores how abundance and spatial localization of CD163+ cells are associated with the biology of MCL, using spatial multiomic investigations of tumor and infiltrating CD163+ and CD3+ cells. A total of 63 proteins wer

Soil Carbon Storage in Temperate Heathland and Forest: What Role Do Ericoid Mycorrhizae Play?

Heathlands have been identified as ecosystems which store large amounts of carbon, especially in soil, which is very important for climate change mitigation. Ericoid mycorrhizae, which are the symbiosis between mycorrhizal fungi and ericaceous plants and which often dominate in heathlands, have been proposed as drivers of soil organic carbon storage through their production of recalcitrant melaniz

Sharing housing: a solution to – or a reflection of – housing inequality?

Shared housing is a rather unusual phenomenon in Sweden. However, due to the decreasing availability of affordable housing and a large share of single-person households in urban areas, sharing is on the rise and new forms of shared housing have entered the market. By analysing how shared housing overlaps with existing patterns of socioeconomic segregation and by interviewing developers of diverse

Natural selection in wild beetle populations

Naturlig selektion i vilda skalbaggspopulationer Naturlig selektion är en nyckelfaktor för evolutionen. Även om vi vet att mängden variation i egenskaper (fenotyper) ger råmaterial för selektion och om den är genetisk påverkar evolutionens hastighet, har vi fortfarande mycket att lära om hur naturlig selektion påverkar specifika egenskaper över tid. I min examensuppsats undersökte jag hur naturliNatural selection is an important force behind evolution. It is well known that phenotypic variation provides opportunity for evolution, but research into how selection acts on specific traits over time is lacking. In this thesis, I studied how selection acts upon the shape and body size of the beetle Cassida viridis. Across three populations, I measured size (length and area), shape, and lifespan

Abundances of disk and bulge giants from high-resolution optical spectra : V. Molybdenum: The p-process element

Aims. In this work, we aim to make a differential comparison of the neutron-capture and p-process element molybdenum (Mo) in the stellar populations in the local disk(s) and the bulge, focusing on minimising possible systematic effects in the analysis. Methods. The stellar sample consists of 45 bulge and 291 local disk K-giants observed with high-resolution optical spectra. The abundances are dete

Method and detector for separation processes

This invention comprises, on one hand, a method of detecting and quantifying components separated by capillary electrophoresis or other technique using thin capillaries in the separation, and on the other hand, an apparatus for performing this detection. The method comprises irradiating the whole or large parts of the capillary at short time intervals and detecting the fluorescence originating fro

Moral Sense and Virtue in Hume’s Ethics

On the face of it, Hume’s understanding of the relationship between virtue and moral sense seems clear enough. According to Hume, a virtue is a quality of mind or character trait that produces approval, and vice a quality of mind that produces blame ( T 614; cp. 473,575). This relationship between virtue and vice and our moral sentiments is described and analysed by Hume as part of his wider and m

Isolation of nucleic acids using a polycationic polymer as precipitation agent

The present invention relates to a method of isolating a desired nucleic acid from a biological solution, which method comprises to selectively precipitate the desired nucleic acid by adding a polycationic precipitating agent to the solution and allowing it to form a complex with said nucleic acid, wherein the precipitating agent is a highly charged linear polymer that comprises quaternary amino g

Capillary assay method

The invention concerns a method for determining the concentration of a constituent in an assay system within a capillary tube from which light is emitted, the light being proportional to the amount of the constituent to be assayed. The light from the system is detected and quantified, and the detection takes place from substantially the longitudinal direction of the capillary tube.

Demonstrating reconfigurability in water-based electromagnetic devices using a 3D-printed siphon

The rise of water-based electromagnetic devices opens up new possibilities for controlling electromagnetic performance due to the liquid state of crucial parts of the device. This letter proposes the siphon mechanism as a novel way to achieve reconfigurability in these types of electromagnetic devices. To demonstrate this, a simple polarization-reconfigurable device based on a siphon is introduced

Strong-coupling effective-field theory for asymmetrically charged plates with counterions only

We are interested in rationalizing the phenomenon of like-charge attraction between charged bodies, such as a pair of colloids, in the strong coupling regime. The two colloids are modelled as uniformly charged parallel plates, neutralized by mobile counterions. In an earlier work [Palaia et al., J. Phys. Chem. B 126, 3143 (2022)1520-610610.1021/acs.jpcb.2c00028], we developed an effective-field th

Nocturnal hypothermia as a migratory strategy in passerines

Involving a controlled reduction of body temperature (lowering of 3 - 10 °C), nocturnal hypothermia is a common strategy among birds to manage the high energy expenditure required for body temperature regulation, particularly during periods of elevated metabolic demands. In this study, I investigated whether migrating passerines generally use controlled nocturnal hypothermia as a migratory strateg

Development of a radial flux machine design environment

This paper focuses on the development of a machine design environment for numeric modelling and analysis of radial flux machines. The design environment is based on Matlab/(Octave) environment, which calls numeric field analysis by FEMM/(Opera-2D). The analysis tool is intended for educational purposes; however it has proved to be a powerful research tool especially at early design stages.

Exploring the time axis within medium-modified jets

In this manuscript, we illustrate how to use the newly proposed τ re-clustering algorithm to select jets with different degrees of quenching without biasing their initial transverse momentum spectrum. Our study is based on Z+jet simulated events using the JEWEL Monte Carlo event generator to account for jet quenching effects. We apply the τ re-clustering algorithm to extract a proxy for a time axi

Performance of the ATLAS forward proton Time-of-Flight detector in Run 2

We present performance studies of the Time-of-Flight (ToF) subdetector of the ATLAS Forward Proton (AFP) detector at the LHC. Efficiencies and resolutions are measured using high-statistics data samples collected at low and moderate pile-up in 2017, the first year when the detectors were installed on both sides of the interaction region. While low efficiencies are observed, of the order of a few p

A Fast Rotating-Mirror Sounder for Dynamic Millimeter-Wave Channel Characterization

A deep understanding of double-directional wireless channels is imperative for wireless system design. This necessitates the development of precise channel models through channel sounding. Given the dynamic nature of wireless channels, a short measurement time is highly desirable. In this paper, we present and validate a dual-polarized millimeter-wave channel sounder that uses a rotating mirror me

Subspace Correction and Domain Decomposition Methods for Total Variation Minimization

The minimization of the total variation is a well-established technique of preservingedges and discontinuities. Therefore it has wide applicability in image processing,where one is interested in recovering a corrupted image while preserving edges inthe image. In the last decades, in the literature, there have been introduced manydifferent approaches and algorithms for minimizing the total variatio

Conditionals

Soloexhibition in Berlin.A conditional sentence is formed by a main clause (the consequence), a conjunction (if), and a conditional clause (the condition). There are four standard types of conditionals. Cesarco’s exhibition proceeds from the given to the not given, comparing what is with what could be or might have been. In some ways, this is equivalent to what happens in the studio, or what happe