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In Arabidopsis thaliana, winter is registered during vernalization through the temperature-dependent repression and epigenetic silencing of floral repressor FLOWERING LOCUS C (FLC). Natural Arabidopsis accessions show considerable variation in vernalization. However, which aspect of the FLC repression mechanism is most important for adaptation to different environments is unclear. By analysing FLC

The transitions between developmental stages are critical points in the Plasmodium life cycle. The development of Plasmodium in the livers of their mammalian hosts bridges malaria transmission and the onset of clinical symptoms elicited by red blood cell infection. The egress of Plasmodium parasites from the liver must be a carefully orchestrated process to ensure a successful switch to the blood

The majority of research in second language acquisition has traditionally focused on classroom-based, instructed learning. However, with the spread of new technologies and the concomitant globalisation of popular culture, informal second language practices (ISLPs; e.g. watching films and television, using social media, or playing video games in another language) are increasingly becoming part of t

Hypertension affects approximately one third of the world’s adult population and is a major cause of premature death despite considerable advances in pharmacological treatments. Growing evidence supports the use of lifestyle interventions for the prevention and adjuvant treatment of hypertension. In this Review, we provide a summary of the epidemiological research supporting the preventive and ant

Context. WASP-121 b is a hot Jupiter that was recently found to possess rich emission (day side) and transmission (limb) spectra, suggestive of the presence of a multitude of chemical species in the atmosphere. Aims. We survey the transmission spectrum of WASP-121 b for line-absorption by metals and molecules at high spectral resolution and elaborate on existing interpretations of the optical tran

Research on the Online Informal Learning of English has found that social media can facilitate language learning, mainly in the domain of vocabulary. It does so not only by providing the necessary language input, but also through the unique ways in which social media platforms encourage interaction between the user and the content as well as with other users. The present study investigated English

Platelets are versatile cells which are capable of eliciting nonhemostatic immune functions, especially under inflammatory conditions. Depending on the specific setting, platelets may be either protective or pathogenic in acute lung injury and acute respiratory distress syndrome (ARDS). Their role in transfusion-related acute lung injury (TRALI) is less well defined; however, it has been hypothesi

Digital and scalable technologies are increasingly important for rapid and large-scale assessment and monitoring of land cover change. Until recently, little research has existed on how these technologies can be specifically applied to the monitoring of Reducing Emissions from Deforestation and Forest Degradation (REDD+) activities. Using the Google Earth Engine (GEE) cloud computing platform, we

We present a model of how counting is learned based on the ability to perform a series of specific steps. The steps require conceptual knowledge of three components: numerosity as a property of collections; numerals; and one-to-one mappings between numerals and collections. We argue that establishing one-to-one mappings is the central feature of counting. In the literature, the so-called cardinali

High spatial resolution X-ray microscopy has become a dedicated tool to study nanocrystals and nanostructure devices in recent years. In general, the spatial resolution of X-ray microscopy depends on the spot size of the X-ray beam and the pixel size of X-ray detectors. High-resolution X-ray detection ideally requires a minimal active region with a sufficient thickness for the X-ray absorption, wh

Objectives: To investigate the prevalence of pathological disease and spectrum of human papillomavirus (HPV) types among symptomatic foreskin tissue. Patients and Methods: Consecutively excised symptomatic foreskins from 351 men were sent for histopathological evaluation. During the surgical procedure, a fresh biopsy was taken for HPV analysis by modified general primer polymerase chain reaction.

Optically stimulated luminescence (OSL) signal properties of pellets from three types of NaCl (two household salts and one analytical grade salt) were investigated for their use in prospective dosimetry. Special attention was given to the OSL signal behaviour with time. The readout protocol was optimised in terms of preheat temperature, and the OSL signal yield of the NaCl pellet with time as well

Purpose: The purpose of the paper is to build on current discussions about the need for and role of guidance in learning and teaching, as well as to theoretically develop its specifics to further advance our scholarly understanding of how to structure and enhance entrepreneurship education. Design/methodology/approach: The paper takes a synthesizing conceptual approach, built on developmental psyc

This thesis examines so-called pancake sentences, an agreement anomaly found in Swedish, Danish and Norwegian. In these languages, predicative adjectives typically agree with their subjects in number and grammatical gender. However, with certain subjects the predicative takes a t-form, corresponding to singular neuter, regardless of the number and gender of the subject. Such sentences are commonlyThis thesis examines so-called pancake sentences, an agreement anomaly found in Swedish, Danish and Norwegian. In these languages, predicative adjectives typically agree with their subjects in number and grammatical gender. However, with certain subjects the predicative takes a t-form, corresponding to singular neuter, regardless of the number and gender of the subject. Such sentences are commonly

The coronavirus disease 2019 (COVID-19) pandemic has created a global health- and economic crisis. Detection of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes COVID-19 by serological methods is important to diagnose a current or resolved infection. In this study, we applied a rapid COVID-19 IgM/IgG antibody test and performed serology assessment of antibody

Excessive risk-taking in markets can have devastating consequences as the latest financial crises have highlighted. In this paper, we ask whether markets as an institution encourages such excessive risk-taking. To establish causality, we isolate the effects of market interaction in a laboratory experiment keeping other possibly confounding factors constant. We find that the opposite is true. Marke

Background: We evaluated outcome after carpal tunnel release (CTR) in patients with clinically diagnosed carpal tunnel syndrome (CTS) but normal results in nerve conduction studies (NCS), and compared these results with those from a prospective group of patients with NCS-verified CTS. Methods: Over a 5-year period, we prospectively included 103 patients with clinical CTS. NCS were done at inclusio

OBJECTIVE: Negative pressure wound therapy (NPWT) is commonly used in the continuous mode. Intermittent pressure therapy (IPT) results in faster wound healing, but it often causes pain. Variable pressure therapy (VPT) has therefore been introduced to provide a smooth transition between 2 different pressure environments, thereby maintaining the negative pressure environment throughout the therapy.

Aims/hypothesis: The risk of complications and medical consequences of type 2 diabetes are well known. Hospital costs have been identified as a key driver of total costs in studies of the economic burden of type 2 diabetes. Less evidence has been generated on the impact of individual diabetic complications on the overall societal burden. The objective of this study was to analyse costs of hospital

Background and purpose — Hallux rigidus (HR) may cause decreased range of motion, joint pain, and gait disturbances. There is a lack of evidence regarding the outcome of different surgical procedures for moderate HR. We report patient-reported outcomes after joint-preserving surgical procedures for moderate HR. Patients and methods — We included 296 patients registered in Swefoot (Swedish national