Irreversible shifts of large-scale components of the Earth system (so-called ‘tipping elements’) on policy-relevant timescales are a major source of uncertainty for projecting the impacts of future climate change. The high latitudes are particularly vulnerable to positive feedbacks that amplify change through atmosphere-ocean-ice interactions. Unfortunately, the short instrumental record does not

The delivery of bio-active molecules through the skin is challenging given the complex structure of its outer layer, the stratum corneum. Here we explore the possibility to encapsulate natural compounds into nanocarriers containing permeation enhancers that can affect the fluidity of the stratum corneum lipids. This approach is expected to facilitate dermal or transdermal release. For this purpose

Typical massive multiple-input multiple-output (MIMO) architectures consider a centralized approach, in which all baseband data received by each antenna has to be sent to a central processing unit (CPU) to be processed. Due to the enormous amount of antennas expected in massive MIMO base stations (BSs), the number of connections to the CPU required in centralized massive MIMO is not scalable. In r

Background: The cultural and language diversity across many European countries presents a range of challenges and opportunities for speech and language therapists and other practitioners working with children with developmental language disorders (DLD) and their families. Objective: The aim of this study was to explore practitioners' perceptions of cultural and linguistic differences in response t

The photocatalytic performance of two-dimensional materials is largely limited by the fast recombination of photogenerated charges. Herein, we design and fabricate a novel g-C3N4/BO0.2N0.8 van der Waals heterostructure to realize oriented charge flow in-plane and separation within the interface. On one hand, a B-C bond forms within the g-C3N4/BO0.2N0.8 interface after the introduction of O atoms.

Aim: Extrauterine growth restriction is common among extremely preterm infants. We explored whether intake of unpasteurised maternal milk (MM) and pasteurised donor milk (DM) was associated with longitudinal growth outcomes and neonatal morbidities in extremely preterm infants. Methods: Observational study of 90 preterm infants born between 2013 and 2015 in Gothenburg, Sweden. Data were prospectiv

Aberrant soluble oligomers formed by the amyloid-β peptide (Aβ) are major pathogenic agents in the onset and progression of Alzheimer’s disease. A variety of biomolecules can influence the formation of these oligomers in the brain, although their mechanisms of action are still largely unknown. Here, we studied the effects on Aβ aggregation of DOPAL, a reactive catecholaldehyde intermediate of dopa

Background: Nutrition and lifestyle have been long established as risk factors for colorectal cancer (CRC). Modifiable lifestyle behaviours bear potential to minimize long-term CRC risk; however, translation of lifestyle information into individualized CRC risk assessment has not been implemented. Lifestyle-based risk models may aid the identification of high-risk individuals, guide referral to sc

Background: General practitioners (GPs) should regularly review patients’ medications and, if necessary, deprescribe, as inappropriate polypharmacy may harm patients’ health. However, deprescribing can be challenging for physicians. This study investigates GPs’ deprescribing decisions in 31 countries. Methods: In this case vignette study, GPs were invited to participate in an online survey contain

Sexual selection has been suggested to accelerate local adaptation and promote evolutionary rescue through several ecological and geneticmechanisms. Condition-dependent sexual selection has mainly been studied in laboratory settings, while data from natural populations are lacking. One ecological factor that can cause condition-dependent sexual selection is parasitism. Here, we quantified ectopara

This paper focuses on the development of 2-terminal CIGS-perovskite tandem solar cells by exploring a range of stack sequences and synthetic procedures for depositing the associated layers. In the end, we converged at a stack sequence composed of SLG/Mo/CIGS/CdS/i-ZnO/ZnO:Al/NiO/PTAA/Perovskite/LiF/PCBM/SnO2/ITO. With this architecture, we reached performances only about 1% lower than the correspo

De iranska ambassaderna runt om i världen bedriver allvarlig brottslighet i form av spionage och terrorism. Därför bör Sverige stänga Irans ambassad, skriver Ardavan Khoshnood.The Iranian embassies around the world conduct serious crimes in the form of espionage and terrorism. Therefore, Sweden should close Iran's embassy, writes Ardavan Khoshnood.

The traditional method for recycling brass chips is to send the scrap back to the material manufacturer for re-melting. Alternatively, brass chips can be reclaimed through hot forging operations at the production site. As an initial screening of the environmental impact of this novel reclamation method, the impacts of this new method was compared to conventional brass production (including recycli

Great social challenges of today, and the conflicts arising therefrom, no longer come one by one. What makes them great is their entanglement in one other and across multiple levels. Similarly, spatial conflicts seldom arise in isolation, but result from simmering tensions that may manifest in a more insidious fashion, namely by appealing to intangible values. This chapter looks into one such spat

Fake canonizations are prevalent in the former communist countries wherein arts and culture in general may still function as propaganda weaponry at the hands of the sponsoring state. The public is almost eliminated from the process of canonization, as the publishing houses, art galleries, and cultural industries seldom survive and flourish from sales to a real public. As a rule, their rarefied pub

Deterministic Lateral Displacement (DLD) is a passive technique employed for particles sorting. We recently introduced a DLD device composed of arrayed three-dimensional metal-covered pillars that can be used to locally apply an electric field. With our system we can exploit the dielectrophoretic (DEP) effect to exert forces on the bioparticles to be sorted, thus dynamically tuning the critical si

In this paper we consider the case of planar motion, where a mobile platform equipped with two cameras moves freely on a planar surface. The cameras are assumed to be directed towards the floor, as well as being connected by a rigid body motion, which constrains the relative motion of the cameras and introduces new geometric constraints. In the existing literature, there are several algorithms ava

Background: In the 1960s only 1/3 of children with soft-tissue sarcomas survived, however with improved treatments survival today has reached 70%. Given the previous poor survival and the rarity of soft-tissue sarcomas, the risk of somatic late effects in a large cohort of Nordic soft-tissue sarcoma survivors has not yet been assessed. Methods: In this population-based cohort study we identified 9

Packed beds are widely used in engineering applications due to their high specific surface area and good heat transfer characteristics. A grille-sphere composite packed bed is proposed previously and has been proved to have higher overall heat transfer coefficient than the simple cubic packing structure. In the present paper, the flow inhomogeneities in both the grille-sphere composite packed bed