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Simultaneous Conduction and Valence Band Quantization in Ultrashallow High-Density Doping Profiles in Semiconductors

We demonstrate simultaneous quantization of conduction band (CB) and valence band (VB) states in silicon using ultrashallow, high-density, phosphorus doping profiles (so-called Si:P δ layers). We show that, in addition to the well-known quantization of CB states within the dopant plane, the confinement of VB-derived states between the subsurface P dopant layer and the Si surface gives rise to a si

Time-resolved surface-enhanced ellipsometric contrast imaging for label-free analysis of biomolecular recognition reactions on glycolipid domains

We have applied surface-enhanced ellipsometry contrast (SEEC) imaging for time-resolved label-free visualization of biomolecular recognition events on spatially heterogeneous supported lipid bilayers (SLB). Using a conventional inverted microscope equipped with total internal reflection (TIR) illumination, biomolecular binding events were monitored with a lateral resolution near the optical diffra

Sealing of submicrometer wells by a shear-driven lipid bilayer

A supported lipid bilayer (SLB) was formed in a microfluidic channel by vesicle fusion. The SLB, formed on a flat part of the surface, was driven by the shear forces of a bulk flow above the SLB to a part of the surface with embedded submicrometer wells. When using a bulk solution with a pH of 9.5 the advancing lipid bilayer sealed the wells, creating free-spanning membranes, whereas at a pH of 8.

Site-specific DNA-controlled fusion of single lipid vesicles to supported lipid bilayers

We investigate the Ca(2+)-triggered fusion of lipid vesicles site-selectively tethered to a DNA-modified supported lipid bilayer array, with the DNA strands designed such that hybridization occurs in a zipperlike fashion. Prior to the addition of Ca(2+), which is observed to induce docking and subsequent fusion (within 200 ms), the vesicles display lateral mobility determined by the number of teth

Kinetic and thermodynamic characterization of single-mismatch discrimination using single-molecule imaging

A single-molecule detection setup based on total internal reflection fluorescence (TIRF) microscopy has been used to investigate association and dissociation kinetics of unlabeled 30mer DNA strands. Single-molecule sensitivity was accomplished by letting unlabeled DNA target strands mediate the binding of DNA-modified and fluorescently labeled liposomes to a DNA-modified surface. The liposomes, ac

Hydrodynamic separation of proteins in supported lipid bilayers confined by gold barriers

Hydrodynamic drag forces generated by liquid flow above a supported lipid bilayer (SLB) can be used to induce lateral movement of molecules protruding from the SLB. Since the velocity of the individual molecules depends on their size and coupling to the lipid bilayer, these forces can also be used to enrich and separate different types of membrane-bound molecules. To improve and better quantify hy

Towards Real-time Time-of-Arrival Self-Calibration using Ultra-Wideband Anchors

Indoor localisation is a currently a key issue, from robotics to the Internet of Things. With hardware advancements making Ultra-Wideband devices more accurate and low powered (potentially even passive), this unlocks the potential of having such devices in common place around factories and homes, enabling an alternative method of navigation. Therefore, anchor calibration indoors becomes a key prob

An experimental comparison of PID autotuners

In this paper two novel autotuners are compared with two industrially available ones. The aim is to see if the research frontline can improve the industry standard of today. Experiments are made on three laboratory processes with different characteristics. Two lag-dominated processes of which one is a level control problem with fast dynamics, and one a temperature control problem with slow dynamic

135La as an Auger-electron emitter for targeted internal radiotherapy

135La has favorable nuclear and chemical properties for Auger-based targeted internal radiotherapy. Here we present detailed investigations of the production, emissions, and dosimetry related to 135La therapy. 135La was produced by 16.5 MeV proton irradiation of metallic natBa on a medical cyclotron, and was isolated and purified by trap-and-release on weak cation-exchange resin. The average produ

Impact of thrombus aspiration on mortality, stent thrombosis, and stroke in patients with ST-segment-elevation myocardial infarction : A report from the Swedish coronary angiography and angioplasty registry

Background--Thrombus aspiration is still being used in a substantial number of patients despite 2 large randomized clinical trials showing no favorable effect of routine thrombus aspiration during primary percutaneous coronary intervention in patients with STsegment- elevation myocardial infarction. The aim of this observational study was to evaluate the impact of thrombus aspiration on mortality,

Association of cerebral amyloid-β Aggregation with cognitive functioning in persons without dementia

IMPORTANCE Cerebral amyloid-β aggregation is an early event in Alzheimer disease (AD). Understanding the association between amyloid aggregation and cognitive manifestation in persons without dementia is important for a better understanding of the course of AD and for the design of prevention trials. OBJECTIVE To investigate whether amyloid-β aggregation is associated with cognitive functioning in

Temperature dependent electronic band structure of wurtzite GaAs nanowires

It has recently become possible to grow GaAs in the wurtzite crystal phase. This ability allows interesting tests of band-structure theory. Wurtzite GaAs has two closely spaced direct conduction bands as well as three nondegenerate valence bands. The energies of the band edges are not well known, in particular not as a function of temperature. In order to improve the accuracy we have studied the t

Numerical analysis of ellipticity condition for large strain plasticity

This paper deals with the numerical investigation of ellipticity of the boundary value problem for isothermal finite strain elasto-plasticity. Ellipticity can be lost when softening occurs. A discontinuity surface then appears in the considered material body and this is associated with the ill-posedness of the boundary value problem. In the paper the condition for ellipticity loss is derived using

Convective heat transfer of parallel-flow and counter-flow double-layer microchannel heat sinks in staggered arrangement

Previous research has proved Double-layer Microchannel Heat Sinks (MHSs) to be efficient ways to improve the cooling performance of electronic devices. However, the cooling potential of the upper working liquid cannot be fully utilized to cool down the substrate with the heated elements. In this sense, a concept of staggered double-layer MHS is proposed and designed. The parallel and counter flow

A modern calamity – Robert Musil on stupidity

Den österrikiske författaren och essäisten Robert Musil förser sociologin med väsentliga reflektioner och problemställningar. Musil för fram diskussioner som överskrider konventionella förståelser av moderniteten – sociologins generella analysobjekt. Artikeln fokuserar på två grundläggande kluster av frågor och begrepp i Musils arbete: människans gestaltlöshet och förhållandet mellan förnuft och kThe writings of the Austrian novelist and essayist Robert Musil provide sociology with vital problems and reflections. Indeed, Musil introduces discussions that extend conventional understanding of modernity – sociology’s general object of analysis. The article focuses on two major sets of questions in Musil’s work: the shapelessness of man and the relation between reason and sentiments. Both prob

Fishing for ways to thrive : Integrating zooarchaeology to understand subsistence strategies and their implications among Early and Middle Mesolithic southern Scandinavian foragers

The purpose of this thesis is to evaluate and deduce the varied lifeways of Early Holocene foragers in southern Scandinavia. By taking an interdisciplinary approach, zooarchaeological data have been applied to the study of different aspects of Early and Middle Mesolithic subsistence, in order to frame a discussion concerning our current understanding of culture and life in early north European soc

Turbulent flux modelling with a simple 2-layer soil model and extrapolated surface temperature applied at Nam Co Lake basin on the Tibetan Plateau

This paper introduces a surface model with two soil-layers for use in a high-resolution circulation model that has been modified with an extrapolated surface temperature, to be used for the calculation of turbulent fluxes. A quadratic temperature profile based on the layer mean and base temperature is assumed in each layer and extended to the surface. The model is tested at two sites on the Tibeta